Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEC/celB   Type   Machinery gene
Locus tag   DK878_RS02760 Genome accession   NZ_CP031379
Coordinates   530384..532621 (+) Length   745 a.a.
NCBI ID   WP_009909666.1    Uniprot ID   A0A7Y6RP41
Organism   Streptococcus suis strain ISU2660     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 525384..537621
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DK878_RS02735 (DK878_02825) - 525454..526383 (-) 930 WP_009909659.1 ABC transporter substrate-binding protein -
  DK878_RS02740 (DK878_02830) - 526380..527180 (-) 801 WP_013730319.1 ABC transporter ATP-binding protein -
  DK878_RS02745 (DK878_02835) - 527333..528778 (-) 1446 WP_013730320.1 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L- lysine ligase -
  DK878_RS02750 (DK878_02840) - 528924..529670 (+) 747 WP_013730321.1 1-acyl-sn-glycerol-3-phosphate acyltransferase -
  DK878_RS02755 (DK878_02845) - 529738..530400 (+) 663 WP_009909665.1 helix-hairpin-helix domain-containing protein -
  DK878_RS02760 (DK878_02850) comEC/celB 530384..532621 (+) 2238 WP_009909666.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  DK878_RS02765 - 532623..532766 (+) 144 WP_002935351.1 transposase -
  DK878_RS02770 (DK878_02855) - 532945..533601 (+) 657 WP_002935353.1 CBS domain-containing protein -
  DK878_RS02775 (DK878_02860) - 533695..534522 (+) 828 WP_002935354.1 hypothetical protein -
  DK878_RS02780 (DK878_02865) - 534528..535799 (+) 1272 WP_002935355.1 toxic anion resistance protein -
  DK878_RS02785 (DK878_02870) - 535836..536702 (-) 867 WP_002935357.1 YitT family protein -
  DK878_RS02790 (DK878_02875) tmk 536877..537515 (+) 639 WP_002935358.1 dTMP kinase -

Sequence

Protein


Download         Length: 745 a.a.        Molecular weight: 84156.93 Da        Isoelectric Point: 7.3957

>NTDB_id=306391 DK878_RS02760 WP_009909666.1 530384..532621(+) (comEC/celB) [Streptococcus suis strain ISU2660]
MSRLSKLPCQPVHLAVLAVAAYFAVHSFSLLTMGLFSLLLAVFGVRQGKTVFLKTLPLLALCGLFFGYQKVQWERADQSA
TEQVTTVQVIPDTIDINGDSLSFRGRADGQTYQVFYKLTSQEEQTYFQKLTGLVQLEVEAEISLPAGQRNFKGFDYQAYL
KTQGIYRTVKITAIKKIVPVQSWNVFDWLSNWRRQALVYVKTNFPAPMSHYMTGLLFGDLDSDFDQMSDLYSSLGIIHLF
ALSGMQVGFVIDKFRWILLRLGLTKETVDKLQIPFSLVYASLTGFSVSVVRSLVQKILGNLGLRKLDNFAVTVFVCLLIL
PRFLLTAGGVLTFTYAFLLTVFDFEDLGQVKKAAVESLSISLGILPVLMTYFYAFQPLSILLTFAFSFVFDVLLLPGLSV
IFLLSPIVKITWVNGFFVFMEKIIVWVADLGLRPWILGKPSELVLLLLLVSLFLLYDFHRRKKWLLGLSLVLALLFFITK
HPLENEVTVVDIGQGDSIFLRDMRGRTVLIDVGGRVDFAAKEAWQERPRQANAERTLIPYLHSRGVDRIDSLVLTHTDTD
HVGDVLEVAKQVQIGRIYVSPGSLTVPDFVATLKEINVPVHVVEVGERLPIFDSYLEVLYPDGTGDGGNNDSIVLYGRLL
KTNFLFTGDLEQGELDLIESYPNLPVDVLKAGHHGSKGSSYPEFLDHIEAKIALVSAGENNRYKHPHQETLERFDSRNIQ
VYRTDQQGAIRFRGWREWRIETVRR

Nucleotide


Download         Length: 2238 bp        

>NTDB_id=306391 DK878_RS02760 WP_009909666.1 530384..532621(+) (comEC/celB) [Streptococcus suis strain ISU2660]
ATGTCACGGTTGAGTAAGCTCCCCTGCCAGCCCGTTCACCTGGCAGTCTTGGCGGTGGCGGCCTACTTTGCAGTCCATTC
TTTTTCCCTCTTGACAATGGGCCTGTTCAGTCTGTTACTGGCTGTCTTTGGTGTTCGGCAAGGTAAGACGGTTTTCCTCA
AAACGCTGCCGCTTTTAGCTCTATGTGGTCTCTTTTTCGGCTACCAAAAGGTCCAATGGGAGCGGGCAGACCAGTCAGCC
ACAGAGCAAGTCACAACTGTGCAGGTCATTCCAGATACTATTGACATTAACGGGGACAGCCTGTCTTTTCGTGGTCGGGC
TGACGGACAAACCTATCAGGTTTTCTATAAATTAACCAGTCAGGAGGAACAGACCTATTTTCAAAAGCTGACAGGTTTGG
TCCAGCTTGAAGTGGAAGCAGAGATCAGTCTGCCAGCTGGTCAGCGGAATTTCAAGGGTTTTGACTATCAGGCCTACCTG
AAAACACAGGGTATTTATCGGACGGTCAAGATTACGGCAATCAAGAAGATTGTCCCAGTCCAGTCTTGGAATGTCTTTGA
CTGGTTGTCAAACTGGCGGAGGCAGGCTTTGGTTTATGTCAAAACCAATTTTCCGGCTCCCATGAGCCACTACATGACAG
GGCTCTTGTTTGGGGACTTGGATAGTGATTTTGACCAGATGAGTGACCTCTATTCCAGTTTGGGTATCATTCATCTCTTT
GCCCTGTCTGGTATGCAGGTGGGCTTTGTCATCGACAAGTTTCGCTGGATTTTACTGCGTTTGGGCTTGACCAAAGAAAC
GGTTGATAAATTACAAATTCCCTTTTCCCTTGTCTATGCGAGCTTGACAGGTTTTTCCGTATCGGTGGTGCGGTCTTTGG
TTCAAAAAATTTTGGGTAATCTGGGCTTGCGGAAGTTGGATAACTTTGCGGTGACAGTTTTTGTCTGTCTGTTGATACTG
CCCCGATTTCTGCTGACAGCTGGTGGTGTCCTGACCTTTACCTATGCTTTTTTGCTGACGGTTTTTGATTTTGAGGACTT
GGGGCAGGTCAAAAAGGCTGCGGTGGAAAGTCTCAGTATTTCACTTGGGATTTTGCCAGTGCTCATGACCTATTTCTATG
CCTTTCAGCCCCTGTCTATCCTCTTGACCTTTGCCTTTTCTTTTGTCTTTGATGTCCTACTCTTGCCAGGCTTGTCAGTC
ATTTTTCTCCTGTCGCCAATCGTCAAGATTACTTGGGTCAACGGATTTTTTGTCTTTATGGAAAAAATCATTGTCTGGGT
GGCGGATTTGGGATTGCGACCTTGGATACTGGGCAAGCCGTCTGAGCTGGTCCTTTTGCTCTTGCTGGTCAGCCTCTTCT
TACTCTACGATTTCCACAGGAGAAAGAAATGGCTTCTAGGACTGAGCTTGGTCCTCGCTCTGCTATTTTTCATAACCAAA
CACCCGCTGGAAAACGAGGTGACGGTGGTGGACATCGGGCAGGGGGACAGCATCTTTTTGCGGGATATGCGGGGGCGGAC
GGTCCTGATTGATGTGGGCGGACGAGTTGATTTTGCGGCCAAGGAAGCGTGGCAGGAGCGGCCTCGGCAGGCAAATGCAG
AGCGGACTTTGATTCCCTATCTGCATAGTCGGGGTGTGGATAGGATTGATAGTTTAGTCCTGACCCACACCGACACAGAC
CATGTGGGGGATGTGCTGGAAGTGGCGAAGCAGGTCCAGATTGGTCGGATTTACGTGTCGCCGGGAAGCCTGACGGTGCC
TGACTTTGTAGCCACCTTGAAAGAAATTAATGTCCCTGTTCATGTTGTTGAGGTGGGCGAACGCTTACCAATTTTTGACT
CTTACCTGGAAGTCCTTTATCCAGATGGGACAGGAGACGGTGGCAATAATGACTCCATTGTCCTTTATGGTCGCTTGCTG
AAAACTAATTTTCTCTTTACAGGGGACTTGGAGCAGGGGGAGTTGGACTTGATAGAATCTTATCCTAACCTGCCTGTCGA
TGTCCTCAAAGCCGGTCACCACGGCTCCAAAGGTTCTTCCTATCCTGAATTTTTGGACCATATCGAAGCCAAGATTGCCT
TGGTATCTGCTGGAGAAAACAACCGCTACAAGCATCCTCACCAAGAAACCTTGGAACGATTTGATAGTCGCAATATCCAA
GTCTATCGTACAGACCAGCAAGGAGCCATTCGCTTCCGAGGTTGGAGGGAGTGGAGGATTGAAACGGTGAGGAGGTAA

Domains

Predicted by InterproScan.

Competence protein (Competence)

(215-461)

Domain of unknown function (DUF4131) (DUF4131)

(29-175)

Metallo-beta-lactamase superfamily (Lactamase_B)

(493-698)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7Y6RP41

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEC/celB Streptococcus mitis SK321

53.992

99.195

0.536
  comEC/celB Streptococcus mitis NCTC 12261

52.861

98.523

0.521
  comEC/celB Streptococcus pneumoniae TIGR4

51.973

98.658

0.513
  comEC/celB Streptococcus pneumoniae Rx1

51.701

98.658

0.51
  comEC/celB Streptococcus pneumoniae D39

51.701

98.658

0.51
  comEC/celB Streptococcus pneumoniae R6

51.701

98.658

0.51
  comEC Lactococcus lactis subsp. cremoris KW2

48.865

100

0.491

Multiple sequence alignment