Detailed information NTG0030639

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: SPCG_RS10130
• Genome accession: NC_010582
• Coordinates: 1918221..1919258 (-)
• Length: 345 a.a.
• NCBI ID: WP_000727272.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae CGSP14
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1913221..1924258

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SPCG_RS10105 (SPCG_1928)	-	1913960..1915291 (-)	1332	WP_000390043.1	hemolysin family protein	-
SPCG_RS10110 (SPCG_1929)	endA	1915582..1916406 (-)	825	WP_001036788.1	DNA-entry nuclease EndA	Machinery gene
SPCG_RS10115	-	1916445..1916633 (-)	189	WP_001813390.1	DNA-directed RNA polymerase subunit beta	-
SPCG_RS10120 (SPCG_1930)	murA	1916626..1917909 (-)	1284	WP_000358028.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
SPCG_RS10125	-	1917933..1918163 (-)	231	WP_000250392.1	DUF1146 family protein	-
SPCG_RS10130 (SPCG_1931)	sepM	1918221..1919258 (-)	1038	WP_000727272.1	SepM family pheromone-processing serine protease	Regulator
SPCG_RS10135 (SPCG_1932)	coaD	1919242..1919730 (-)	489	WP_001280736.1	pantetheine-phosphate adenylyltransferase	-
SPCG_RS10140 (SPCG_1933)	rsmD	1919720..1920259 (-)	540	WP_000706966.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
SPCG_RS10145 (SPCG_1934)	asnA	1920324..1921316 (-)	993	WP_000747993.1	aspartate--ammonia ligase	-
SPCG_RS10155 (SPCG_1936)	-	1921428..1922111 (-)	684	WP_001016917.1	Bax inhibitor-1/YccA family protein	-
SPCG_RS10160 (SPCG_1937)	-	1922167..1922907 (-)	741	WP_000152680.1	RNA methyltransferase	-
SPCG_RS10165 (SPCG_1938)	-	1922941..1923219 (+)	279	WP_001174613.1	acylphosphatase	-
SPCG_RS10170 (SPCG_1939)	yidC	1923297..1924223 (+)	927	WP_000835955.1	membrane protein insertase YidC	-

Sequence

Protein

• Length: 345 a.a.
• Molecular weight: 37506.54 Da
• Isoelectric Point: 5.0724

>NTDB_id=30639 SPCG_RS10130 WP_000727272.1 1918221..1919258(-) (sepM) [Streptococcus pneumoniae CGSP14]
MKKKIRWPLYVIAALIVTFLAFVVPLPYYIEVPGGSEDIRQVLKVNDTEDKEAGAYQFVTVGVQHATLAHMIYAWLTPFT
DIRSAQETTGGSSDVEFLRINQFYMQTSQNMAKYQGLKTAGKDIELKYFGVYVLNVTDNSTFKGILNISDTVTAVNDQTF
DSSKDLIDYVSSQKLGDSVKVTYEEDGQTKSAEGKIITLENGKNGIGIGLIDRTEVISNVPISFSTAGIGGPSAGLMFSL
AIYTQIAHPDLRNGRIVAGTGTIDRDGNVGDIGGIDKKVLASARAGAAIFFAPDNPVSEEEQKAHPDAKNNYQTALEAAK
TIKTDMKIVPVKTLQDAIDYLKNSP

Nucleotide

• Length: 1038 bp

>NTDB_id=30639 SPCG_RS10130 WP_000727272.1 1918221..1919258(-) (sepM) [Streptococcus pneumoniae CGSP14]
ATGAAAAAAAAGATTAGATGGCCCTTATACGTCATTGCGGCCTTGATTGTGACTTTCTTGGCATTTGTAGTGCCCTTGCC
TTATTATATAGAGGTTCCAGGTGGTTCGGAAGATATTCGCCAAGTCCTTAAAGTAAATGACACAGAAGATAAGGAAGCTG
GTGCCTATCAATTCGTTACGGTTGGTGTTCAACATGCCACTTTAGCTCATATGATTTATGCTTGGTTGACACCTTTTACA
GATATTCGTAGTGCTCAGGAGACTACAGGTGGTTCTTCCGATGTTGAATTTCTGCGAATCAATCAATTCTACATGCAAAC
ATCGCAAAATATGGCCAAGTATCAAGGACTAAAAACAGCTGGTAAGGATATCGAACTCAAGTACTTTGGAGTTTATGTTT
TGAATGTGACGGATAATTCAACCTTTAAAGGGATTCTCAATATCTCTGATACGGTCACAGCAGTCAATGATCAGACCTTT
GATAGTTCCAAAGACTTGATTGATTACGTCAGTTCTCAAAAATTAGGGGATTCCGTCAAGGTCACCTATGAAGAGGATGG
GCAAACCAAGTCTGCAGAAGGAAAAATCATCACCTTGGAAAATGGCAAAAATGGAATTGGAATCGGCTTGATTGACCGTA
CAGAGGTAATCAGCAATGTCCCAATTAGCTTTTCAACAGCTGGTATTGGCGGTCCAAGTGCTGGTCTCATGTTTAGTCTA
GCTATCTATACTCAAATAGCTCACCCAGATCTTCGTAATGGTCGTATTGTTGCCGGTACAGGTACCATTGACCGCGATGG
TAATGTGGGAGACATTGGAGGTATTGATAAGAAGGTTTTAGCTTCGGCTAGGGCAGGTGCTGCTATTTTCTTTGCTCCTG
ATAACCCTGTTAGCGAAGAAGAACAAAAGGCGCATCCGGACGCGAAAAACAACTACCAAACAGCCCTAGAAGCGGCTAAA
ACAATCAAGACGGATATGAAAATCGTGCCCGTTAAAACCCTACAAGATGCGATTGATTACTTGAAAAACAGTCCCTAA

Domains

Predicted by InterproScan.

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (230-296)

• PDZ domain (PDZ_2) (130-193)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	59.706	98.551	0.588