Detailed information    

insolico Bioinformatically predicted

Overview

Name   stkP   Type   Regulator
Locus tag   DK237_RS08930 Genome accession   NZ_CP031377
Coordinates   1765536..1767530 (-) Length   664 a.a.
NCBI ID   WP_009909429.1    Uniprot ID   -
Organism   Streptococcus suis strain ISU2614     
Function   require for competence development; phosphorylate ComE (predicted from homology)   
Competence regulation

Genomic Context

Location: 1760536..1772530
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DK237_RS08905 (DK237_09160) - 1760971..1761342 (-) 372 WP_002937017.1 S1 RNA-binding domain-containing protein -
  DK237_RS08910 (DK237_09165) - 1761344..1762744 (-) 1401 WP_002937018.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  DK237_RS08915 (DK237_09170) - 1762794..1763435 (-) 642 WP_002937025.1 response regulator transcription factor -
  DK237_RS08920 (DK237_09175) - 1763407..1764423 (-) 1017 WP_002937028.1 sensor histidine kinase -
  DK237_RS08925 (DK237_09180) liaF 1764420..1765079 (-) 660 WP_226964025.1 cell wall-active antibiotics response protein LiaF -
  DK237_RS08930 (DK237_09185) stkP 1765536..1767530 (-) 1995 WP_009909429.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  DK237_RS08935 (DK237_09190) - 1767530..1768267 (-) 738 WP_012774983.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  DK237_RS08940 (DK237_09195) rsmB 1768305..1769618 (-) 1314 WP_074412645.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  DK237_RS08945 (DK237_09200) fmt 1769605..1770543 (-) 939 WP_009909423.1 methionyl-tRNA formyltransferase -

Sequence

Protein


Download         Length: 664 a.a.        Molecular weight: 71226.76 Da        Isoelectric Point: 6.5350

>NTDB_id=306360 DK237_RS08930 WP_009909429.1 1765536..1767530(-) (stkP) [Streptococcus suis strain ISU2614]
MIQIGKIFAGRYRIVRQIGRGGMADVYLARDLILDGEEVAVKVLRTNYQTDQIAIQRFQREARAMAELDHPNIVRISDIG
EEDGQQYLAMEYVNGLDLKRYIKENAPLSNDVAVRIMGQILLAMRMAHTRGIVHRDLKPQNVLLTSNGVAKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATIQSDIYAMGIILFEMLTGRIPYDGDSAVTIALQHFQKPLPSVREENANVP
QALENVVLKATAKKLNERYKSVAEMYADLASALSMDRQNEPRVELEGNKVDTKTLPKLSQANVETKVPHTNSSAQVSATD
KGSGKKEVAKSGNKPVSKPRPGIRTRYKVLIGAILLTVIAAGLMFFNAPRTVTVPDVSGQTVEKATEMIEVAGLEVGNIT
EEATATVDEGLVIRTSPAAKTTRRQGSKIDIVVATAALASIPDVVDKESDTARQELEALGFQVTIKEEYSEKVAQGLVIK
TDPGANSSAEKGAKITLYVSKGVAPQVVPNVVGKSQENATQILQTAGFSIGTITQEYSSSVTAGQVISTDPVANTELAKG
SIINLVISKGKELIMPDLTSGNYTYSQARSQLQALGVNAESIEKQEDRSYYSTTSDIVIGQYPAAGATIDGTVTLYVSVA
STRTSSDSSAGSSTSTSTSTGSGQ

Nucleotide


Download         Length: 1995 bp        

>NTDB_id=306360 DK237_RS08930 WP_009909429.1 1765536..1767530(-) (stkP) [Streptococcus suis strain ISU2614]
ATGATTCAAATCGGTAAGATCTTTGCCGGTCGGTATCGAATCGTTCGGCAAATTGGTCGAGGCGGTATGGCAGATGTTTA
CCTAGCAAGAGATTTGATTTTAGATGGAGAAGAGGTTGCTGTTAAAGTTCTTCGGACCAACTATCAGACAGATCAAATTG
CTATCCAGCGTTTTCAACGTGAAGCGCGTGCCATGGCAGAACTTGACCATCCCAATATCGTTCGTATTTCGGACATCGGT
GAAGAAGATGGTCAACAGTATCTGGCTATGGAATATGTCAATGGCCTCGATTTAAAACGTTATATAAAAGAAAATGCACC
ACTTTCCAACGATGTTGCGGTGCGAATTATGGGACAGATTCTCCTTGCTATGCGCATGGCGCACACGAGAGGAATTGTCC
ATCGAGATTTGAAACCTCAGAACGTCCTTTTGACTTCCAATGGAGTCGCTAAAGTAACAGACTTTGGTATTGCAGTTGCC
TTTGCTGAAACGAGTTTGACACAAACCAACTCCATGTTGGGTTCTGTTCACTATCTTTCACCTGAGCAGGCGCGTGGTTC
GAAAGCGACCATTCAAAGTGATATTTATGCGATGGGAATCATCCTTTTTGAAATGTTGACGGGTCGCATTCCCTATGATG
GAGACAGTGCTGTGACGATCGCTCTTCAGCATTTCCAAAAACCTCTCCCATCTGTTAGAGAAGAGAATGCCAACGTACCT
CAGGCCTTAGAAAATGTTGTACTAAAAGCAACGGCAAAAAAATTAAACGAGCGCTATAAGTCGGTTGCAGAAATGTATGC
AGATTTAGCTTCGGCTCTATCCATGGATCGTCAGAATGAACCCAGGGTTGAACTAGAAGGGAACAAGGTTGATACAAAAA
CCTTGCCGAAACTCTCCCAAGCCAATGTTGAAACGAAAGTACCGCATACAAACAGTTCTGCTCAAGTTTCTGCGACGGAT
AAGGGGTCTGGTAAGAAAGAAGTGGCGAAGTCGGGAAATAAGCCTGTTTCAAAACCAAGGCCAGGCATACGTACACGCTA
CAAAGTCTTGATAGGAGCTATTTTGTTAACAGTCATAGCGGCTGGACTCATGTTTTTCAACGCTCCACGAACAGTTACAG
TCCCTGATGTATCTGGTCAAACCGTTGAAAAAGCTACAGAAATGATTGAAGTGGCAGGATTGGAAGTTGGAAATATCACA
GAAGAAGCGACAGCGACTGTAGATGAAGGCTTGGTAATACGGACCTCTCCGGCTGCAAAGACGACCAGACGTCAAGGGAG
TAAGATTGATATTGTAGTAGCAACGGCTGCGCTGGCATCTATTCCAGATGTGGTGGATAAGGAGTCTGATACTGCGCGGC
AGGAATTGGAGGCCCTTGGTTTCCAAGTGACAATAAAAGAAGAATATAGCGAAAAAGTTGCCCAAGGACTCGTTATCAAA
ACAGATCCAGGAGCAAATAGTTCTGCTGAGAAGGGTGCAAAAATTACCCTTTACGTTTCCAAAGGAGTGGCGCCACAAGT
TGTTCCAAACGTTGTTGGAAAAAGTCAGGAGAATGCTACTCAAATTCTTCAGACAGCAGGCTTCAGCATTGGAACCATTA
CTCAGGAATATAGCTCATCTGTTACTGCAGGTCAGGTTATCAGCACAGATCCCGTTGCCAATACAGAGTTGGCAAAAGGT
TCTATCATCAATCTAGTTATTTCAAAAGGAAAAGAATTGATTATGCCTGATTTAACATCTGGCAATTACACCTATTCACA
GGCGCGTAGTCAATTACAAGCCTTGGGTGTCAATGCGGAAAGTATTGAAAAACAAGAAGATAGAAGCTATTATTCAACGA
CAAGTGACATCGTCATTGGACAATATCCTGCTGCTGGAGCAACAATTGATGGAACAGTTACCTTGTATGTCTCTGTTGCA
TCAACCAGAACCAGTAGCGATTCTTCAGCAGGAAGTTCCACAAGTACAAGTACTTCAACAGGTAGCGGACAATAA

Domains

Predicted by InterproScan.

PASTA domain (PASTA)

(574-638)

PASTA domain (PASTA)

(372-434)

PASTA domain (PASTA)

(507-569)

PASTA domain (PASTA)

(441-501)

Protein kinase domain (Pkinase)

(12-240)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  stkP Streptococcus pneumoniae TIGR4

52.03

100

0.521
  stkP Streptococcus pneumoniae D39

52.03

100

0.521
  stkP Streptococcus pneumoniae R6

52.03

100

0.521
  stkP Streptococcus pneumoniae Rx1

51.88

100

0.52
  stkP/pknB Streptococcus salivarius strain HSISS4

51.171

90.06

0.461
  pknB Streptococcus mutans UA159

54.529

81.476

0.444

Multiple sequence alignment