Detailed information NTG0030633

Bioinformatically predicted

Overview

• Name: comGF
• Type: Machinery gene
• Locus tag: SDEG_RS00680
• Genome accession: NC_012891
• Coordinates: 115014..115454 (+)
• Length: 146 a.a.
• NCBI ID: WP_003061780.1
• Uniprot ID: -
• Organism: Streptococcus dysgalactiae subsp. equisimilis GGS_124
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 110014..120454

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SDEG_RS00650 (SDEG_0133)	-	111695..112060 (+)	366	WP_012766445.1	DUF1033 family protein	-
SDEG_RS00655 (SDEG_0134)	comGA/cglA	112141..113082 (+)	942	WP_003062163.1	competence type IV pilus ATPase ComGA	Machinery gene
SDEG_RS00660 (SDEG_0135)	comGB	113018..114049 (+)	1032	WP_015057201.1	competence type IV pilus assembly protein ComGB	Machinery gene
SDEG_RS00665 (SDEG_0136)	comGC	114051..114377 (+)	327	WP_003055259.1	competence type IV pilus major pilin ComGC	Machinery gene
SDEG_RS00670 (SDEG_0137)	comGD	114352..114780 (+)	429	WP_041788719.1	competence type IV pilus minor pilin ComGD	Machinery gene
SDEG_RS00675 (SDEG_0138)	comGE	114788..115033 (+)	246	WP_003058569.1	competence type IV pilus minor pilin ComGE	Machinery gene
SDEG_RS00680 (SDEG_0139)	comGF	115014..115454 (+)	441	WP_003061780.1	competence type IV pilus minor pilin ComGF	Machinery gene
SDEG_RS00685 (SDEG_0140)	comGG	115483..115806 (+)	324	WP_227985720.1	competence type IV pilus minor pilin ComGG	-
SDEG_RS00690 (SDEG_0141)	comGH	115869..116822 (+)	954	WP_003060701.1	class I SAM-dependent methyltransferase	Machinery gene
SDEG_RS00695 (SDEG_0142)	-	116881..118077 (+)	1197	WP_012766450.1	acetate kinase	-
SDEG_RS00700 (SDEG_0143)	-	118384..118590 (+)	207	WP_003058508.1	helix-turn-helix transcriptional regulator	-
SDEG_RS00705 (SDEG_0144)	-	118693..119373 (+)	681	WP_012766451.1	CPBP family intramembrane glutamic endopeptidase	-
SDEG_RS00710 (SDEG_0145)	-	119391..119828 (+)	438	WP_012766452.1	hypothetical protein	-

Sequence

Protein

• Length: 146 a.a.
• Molecular weight: 16969.55 Da
• Isoelectric Point: 10.6305

>NTDB_id=30633 SDEG_RS00680 WP_003061780.1 115014..115454(+) (comGF) [Streptococcus dysgalactiae subsp. equisimilis GGS_124]
MKKRTGRVQAFTFLEALIALLVISGSLLVYQGLTKTLLSHSRYLTKNDQDHWLLFSQQLREELSGARFHKVENNKLYIEK
GKKKLVLGQFKSHDFRKSAGNGQGYQPMLFGLSHSHIQAEQSRIRITLHWKSGLERTFYYAFQDQP

Nucleotide

• Length: 441 bp

>NTDB_id=30633 SDEG_RS00680 WP_003061780.1 115014..115454(+) (comGF) [Streptococcus dysgalactiae subsp. equisimilis GGS_124]
TTGAAAAAAAGGACAGGTAGGGTCCAAGCATTTACTTTTTTAGAGGCTTTAATTGCCTTACTGGTGATATCAGGTTCTCT
TCTAGTGTATCAAGGATTGACCAAAACACTCCTTAGCCACAGTCGCTACCTTACCAAAAATGATCAAGACCATTGGCTTT
TGTTCTCCCAGCAGTTACGAGAAGAGTTAAGTGGAGCGCGATTTCACAAAGTAGAGAACAATAAATTATATATCGAAAAA
GGCAAGAAAAAACTAGTTTTAGGACAATTTAAAAGCCATGACTTTCGAAAATCGGCAGGCAATGGACAAGGTTATCAACC
CATGCTGTTTGGCCTGTCTCATAGTCATATACAAGCAGAGCAGTCTCGTATTCGTATTACCCTTCACTGGAAAAGTGGAC
TAGAAAGGACCTTCTACTATGCGTTTCAAGACCAACCTTAA

Domains

Predicted by InterProScan.

• Putative Competence protein ComGF (ComGF) (40-135)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGF	Streptococcus mutans UA159	48.921	95.205	0.466
comGF	Streptococcus mutans UA140	48.201	95.205	0.459
comGF	Lactococcus lactis subsp. cremoris KW2	46.377	94.521	0.438
comGF/cglF	Streptococcus mitis NCTC 12261	43.796	93.836	0.411
comGF/cglF	Streptococcus pneumoniae R6	43.796	93.836	0.411
comGF/cglF	Streptococcus pneumoniae TIGR4	43.796	93.836	0.411
comGF/cglF	Streptococcus pneumoniae D39	43.796	93.836	0.411
comGF/cglF	Streptococcus mitis SK321	43.796	93.836	0.411
comGF/cglF	Streptococcus pneumoniae Rx1	43.796	93.836	0.411