Detailed information NTG0305106

Bioinformatically predicted

Overview

• Name: pilC
• Type: Machinery gene
• Locus tag: DV401_RS04785
• Genome accession: NZ_CP031254
• Coordinates: 937295..938512 (+)
• Length: 405 a.a.
• NCBI ID: WP_114877325.1
• Uniprot ID: -
• Organism: Haemophilus influenzae strain M25588
• Function: type IV pilus biogenesis and function (predicted from homology) DNA binding and uptake

Genomic Context

Location: 932295..943512

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DV401_RS04765	corC	933262..934161 (-)	900	WP_005656283.1	CNNM family magnesium/cobalt transport protein CorC	-
DV401_RS04770	ampD	934792..935343 (-)	552	WP_071162800.1	1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD	-
DV401_RS04775	pilA	935458..935907 (+)	450	WP_103708055.1	prepilin-type N-terminal cleavage/methylation domain-containing protein	Machinery gene
DV401_RS04780	pilB	935904..937298 (+)	1395	WP_114877323.1	GspE/PulE family protein	Machinery gene
DV401_RS04785	pilC	937295..938512 (+)	1218	WP_114877325.1	type II secretion system F family protein	Machinery gene
DV401_RS04790	pilD	938509..939201 (+)	693	WP_114877327.1	prepilin peptidase	Machinery gene
DV401_RS04795	rho	939255..940517 (-)	1263	WP_005666690.1	transcription termination factor Rho	-
DV401_RS04800	metJ	940752..941069 (+)	318	WP_005634287.1	met regulon transcriptional regulator MetJ	-
DV401_RS04805	cueR	941083..941469 (-)	387	WP_114877329.1	Cu(I)-responsive transcriptional regulator	-
DV401_RS04810	-	941546..941752 (+)	207	WP_005654130.1	heavy-metal-associated domain-containing protein	-

Sequence

Protein

• Length: 405 a.a.
• Molecular weight: 46049.18 Da
• Isoelectric Point: 9.7235

>NTDB_id=305106 DV401_RS04785 WP_114877325.1 937295..938512(+) (pilC) [Haemophilus influenzae strain M25588]
MTKKLFYYQGSNALNQKQKGSIIADTKQQAHFQLISHGLTHIKLQQNWQFGAKPKNSEISELLNQLATLLQSAIPLKNSL
QILQQNCTQIMLNEWLERLLQSIESGLAFSQAIEQQGKYLTQQEIQLIQVGEMTGKLAVVCKKIATHRSQSLALQRKLQK
IMLYPSMVLGISLLLTLALLLFIVPQFAEMYSGNNAELPTITAILLSISNFLKQNIGILLFFALSFVLFYYFYLKRQTWF
HQKKNQLISITPIFGTIQKLSRLVNFSQSLQIMLQAGVPLNQALDSFLPRTQTWQTKTLVNDIVLDKEVRSILQWVSQGY
AFSNSVSSDLFPMEAQQMLQIGEQSGKLTLMLEHIADNYQEKLNHQIDLLSQMLEPLMMVIIGSLIGIIMMGMYLPIFNM
GSVIQ

Nucleotide

• Length: 1218 bp

>NTDB_id=305106 DV401_RS04785 WP_114877325.1 937295..938512(+) (pilC) [Haemophilus influenzae strain M25588]
ATGACTAAAAAACTCTTTTATTATCAAGGTAGTAACGCATTAAATCAGAAACAAAAAGGCTCAATTATTGCGGATACGAA
ACAACAAGCACACTTTCAGTTAATAAGCCACGGGCTTACTCACATCAAATTACAACAAAACTGGCAATTTGGGGCAAAGC
CCAAAAATTCAGAAATCAGTGAATTACTCAATCAATTAGCGACACTACTACAATCTGCCATTCCGTTAAAAAACAGCCTG
CAAATTTTGCAACAAAATTGTACTCAAATTATGCTCAACGAATGGCTTGAACGACTGCTTCAATCCATTGAATCTGGCTT
AGCATTCTCACAAGCCATTGAACAACAAGGAAAATATCTCACACAACAAGAAATTCAACTGATTCAAGTGGGAGAAATGA
CAGGAAAACTTGCCGTTGTTTGTAAAAAAATAGCCACGCACCGTAGTCAATCTTTGGCTTTACAACGCAAATTACAGAAA
ATTATGTTATATCCCTCAATGGTATTGGGAATTTCTCTATTATTGACACTCGCATTACTGCTTTTTATCGTGCCTCAATT
TGCTGAAATGTACAGTGGCAATAATGCCGAATTACCAACAATAACTGCAATATTGCTCTCTATATCCAATTTTCTTAAGC
AAAATATTGGCATTTTGCTATTTTTCGCTTTGAGTTTTGTTCTATTTTATTACTTCTATCTAAAACGCCAGACTTGGTTT
CATCAAAAGAAAAATCAACTTATTTCTATCACGCCTATTTTTGGCACAATTCAAAAACTTTCACGTTTAGTGAACTTTAG
TCAAAGTTTACAAATTATGTTGCAGGCTGGCGTACCGCTTAATCAAGCACTAGACAGTTTTCTCCCTCGCACACAAACGT
GGCAAACCAAGACGCTTGTAAATGACATCGTATTAGATAAAGAAGTGCGGTCAATTTTACAATGGGTTTCTCAAGGCTAT
GCGTTTTCTAATAGCGTAAGTAGCGATCTTTTCCCGATGGAAGCACAACAAATGTTACAAATTGGCGAGCAAAGCGGAAA
ACTCACTTTGATGCTAGAGCATATTGCGGATAATTACCAAGAAAAACTTAATCATCAAATTGACTTACTCTCGCAAATGC
TAGAACCATTAATGATGGTAATTATCGGCAGTCTGATTGGAATTATTATGATGGGAATGTATTTACCTATCTTTAATATG
GGCTCTGTTATTCAATGA

Domains

Predicted by InterproScan.

• Type II secretion system (T2SS), protein F (T2SSF) (63-185)

• Type II secretion system (T2SS), protein F (T2SSF) (266-396)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilC	Haemophilus influenzae 86-028NP	97.783	100	0.98
pilC	Haemophilus influenzae Rd KW20	97.537	100	0.978
pilC	Glaesserella parasuis strain SC1401	38.5	98.765	0.38