Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   EXA09_RS05500 Genome accession   NZ_CP035812
Coordinates   1187001..1187591 (+) Length   196 a.a.
NCBI ID   WP_000633668.1    Uniprot ID   P0AGA7
Organism   Escherichia coli strain B7A     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1182001..1192591
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EXA09_RS05470 emrD 1182484..1183668 (-) 1185 WP_000828746.1 multidrug efflux MFS transporter EmrD -
  EXA09_RS05475 ysdE 1183750..1183824 (+) 75 WP_211180519.1 protein YsdE -
  EXA09_RS05480 tisB 1184087..1184176 (-) 90 WP_000060506.1 type I toxin-antitoxin system toxin TisB -
  EXA09_RS05485 ivbL 1184740..1184838 (+) 99 WP_001315912.1 ilvB operon leader peptide IvbL -
  EXA09_RS05490 ilvB 1184944..1186632 (+) 1689 WP_000168480.1 acetolactate synthase large subunit -
  EXA09_RS05495 ilvN 1186636..1186926 (+) 291 WP_001181713.1 acetolactate synthase small subunit -
  EXA09_RS05500 letA 1187001..1187591 (+) 591 WP_000633668.1 transcriptional regulator UhpA Regulator
  EXA09_RS05505 uhpB 1187591..1189093 (+) 1503 WP_001295243.1 signal transduction histidine-protein kinase/phosphatase UhpB -
  EXA09_RS05510 uhpC 1189103..1190422 (+) 1320 WP_001296914.1 MFS transporter family glucose-6-phosphate receptor UhpC -
  EXA09_RS05515 uhpT 1190560..1191951 (+) 1392 WP_001296910.1 hexose-6-phosphate:phosphate antiporter -

Sequence

Protein


Download         Length: 196 a.a.        Molecular weight: 20889.30 Da        Isoelectric Point: 5.9982

>NTDB_id=305053 EXA09_RS05500 WP_000633668.1 1187001..1187591(+) (letA) [Escherichia coli strain B7A]
MITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLPGRGVQVCICDISMPDISGLELLSQLPKGMATIMLSV
HDSPALVEQALNAGARGFLSKRCSPDELIAAVHTVATGGCYLTPDIAIKLASGRQDPLTKRERQVAEKLAQGMAVKEIAA
ELGLSPKTVHVHRANLMEKLGVSNDVELARRMFDGW

Nucleotide


Download         Length: 591 bp        

>NTDB_id=305053 EXA09_RS05500 WP_000633668.1 1187001..1187591(+) (letA) [Escherichia coli strain B7A]
ATGATCACCGTTGCCCTTATAGACGATCACCTCATCGTCCGCTCCGGCTTTGCGCAGCTGCTGGGGCTGGAACCTGATTT
GCAGGTAGTTGCCGAGTTTGGTTCGGGGCGCGAGGCGCTGGCGGGGCTGCCGGGGCGCGGTGTGCAGGTGTGTATTTGCG
ATATCTCCATGCCCGATATCTCCGGTCTGGAACTGCTAAGCCAGCTGCCGAAAGGTATGGCGACAATAATGCTCTCTGTT
CATGACAGTCCGGCGCTGGTTGAGCAGGCGCTTAACGCGGGGGCGCGCGGCTTTCTCTCCAAACGCTGTAGCCCTGACGA
ACTGATTGCGGCGGTGCATACGGTTGCTACGGGCGGCTGTTATCTGACGCCGGATATTGCCATTAAACTGGCATCCGGTC
GTCAGGACCCGCTGACCAAACGTGAACGCCAGGTGGCGGAAAAACTGGCGCAAGGAATGGCGGTGAAAGAGATTGCCGCC
GAACTGGGCTTGTCACCGAAAACGGTACACGTCCATCGCGCCAATCTGATGGAAAAACTGGGCGTCAGTAACGACGTAGA
ACTGGCGCGCCGCATGTTTGATGGCTGGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(136-191)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P0AGA7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

38.5

100

0.393
  letA Legionella pneumophila strain ERS1305867

38.5

100

0.393
  degU Bacillus subtilis subsp. subtilis str. 168

33.184

100

0.378

Multiple sequence alignment