Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB   Type   Regulator
Locus tag   DV129_RS07560 Genome accession   NZ_CP031247
Coordinates   1407349..1408698 (-) Length   449 a.a.
NCBI ID   WP_000801608.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain M23734     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 1402349..1413698
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DV129_RS07545 - 1402545..1406270 (-) 3726 WP_000361197.1 phosphoribosylformylglycinamidine synthase -
  DV129_RS12650 - 1406351..1406461 (-) 111 WP_078065395.1 phosphoribosylaminoimidazolesuccinocarboxamide synthase -
  DV129_RS07555 purC 1406472..1407179 (-) 708 WP_000043300.1 phosphoribosylaminoimidazolesuccinocarboxamide synthase -
  DV129_RS07560 comB 1407349..1408698 (-) 1350 WP_000801608.1 competence pheromone export protein ComB Regulator
  DV129_RS07565 comA 1408711..1410864 (-) 2154 WP_114865983.1 peptide cleavage/export ABC transporter ComA Regulator
  DV129_RS12535 - 1411451..1411576 (-) 126 WP_000346297.1 PncF family bacteriocin immunity protein -
  DV129_RS07570 blpU 1411579..1411809 (-) 231 WP_001093075.1 bacteriocin-like peptide BlpU -
  DV129_RS07575 - 1412012..1412302 (-) 291 Protein_1432 IS5/IS1182 family transposase -
  DV129_RS07580 - 1412348..1412581 (-) 234 WP_000136447.1 acyl carrier protein -
  DV129_RS07585 plsX 1412587..1413579 (-) 993 WP_000717461.1 phosphate acyltransferase PlsX -

Sequence

Protein


Download         Length: 449 a.a.        Molecular weight: 49601.44 Da        Isoelectric Point: 5.3895

>NTDB_id=304770 DV129_RS07560 WP_000801608.1 1407349..1408698(-) (comB) [Streptococcus pneumoniae strain M23734]
MKPEFLESAEFYNRRYHNFSSSVIVPMALLLVFLLGFATVAEKEMSLSTRATVEPSRILANIQSTSNNRILVNHLEENKL
VKKGDLLVQYQEGAEGVQAESYASQLDMLKDQKKQLEYLQKSLQEGENHFPEEDKFGYQATFRDYISQAGSLRASTSQQN
ETIASQNAAASQTQAEIGNLISQTEAKIRDYQTAKSAIETGASLAGQNLAYSFYQSYKSQGEENPQTKVQAVAQVEAQIS
QLESSLATYRVQYAGSGTQQAYASGLSSQLESLKSQHLAKVGQELTLLAQKILEAESGKKVQGNLLDKGKITASEDGVLH
LNPETSDSSMVAEGALLAQLYPSLEREGKAKLTAYLSSKDVARIKVGDSVRYTTTHDAGNQLFLDSTITSIDATATKTEK
GNFFKIEAETNLTSEQAEKLRYGVEGRLQMITGKKSYLRYYLDQFLNKE

Nucleotide


Download         Length: 1350 bp        

>NTDB_id=304770 DV129_RS07560 WP_000801608.1 1407349..1408698(-) (comB) [Streptococcus pneumoniae strain M23734]
ATGAAACCAGAATTTTTAGAAAGTGCGGAGTTTTATAATCGTCGTTACCATAATTTTTCCAGTAGTGTGATTGTACCCAT
GGCCCTTCTGCTCGTGTTTTTACTTGGCTTTGCAACTGTTGCAGAGAAGGAGATGAGTTTGTCCACTAGAGCTACTGTCG
AACCTAGTCGTATTCTTGCAAATATCCAGTCAACTAGCAACAATCGTATTCTTGTCAATCATTTGGAAGAAAATAAGCTG
GTTAAGAAGGGGGATCTTTTGGTTCAATACCAAGAAGGGGCAGAGGGTGTCCAAGCGGAGTCCTATGCCAGTCAGTTGGA
CATGCTAAAGGATCAAAAAAAGCAATTGGAGTATCTGCAAAAGAGCCTGCAAGAAGGGGAGAACCACTTTCCAGAGGAGG
ATAAGTTTGGCTACCAAGCCACCTTTCGCGACTACATCAGTCAAGCAGGCAGTCTTAGGGCTAGTACATCGCAACAAAAT
GAGACCATCGCGTCCCAGAATGCAGCAGCTAGCCAAACCCAAGCCGAAATCGGCAACCTCATCAGTCAAACAGAGGCTAA
AATTCGCGATTACCAGACAGCTAAGTCAGCTATTGAAACAGGTGCTTCCTTGGCCGGTCAGAATCTAGCCTACTCTTTTT
ACCAGTCCTACAAGTCTCAGGGCGAGGAAAATCCCCAAACTAAGGTTCAGGCAGTTGCACAGGTTGAAGCACAGATTTCT
CAGTTAGAATCTAGTCTTGCTACTTACCGTGTCCAGTATGCAGGTTCAGGTACCCAGCAAGCCTATGCGTCAGGGTTAAG
CAGTCAATTGGAATCCCTTAAATCCCAACACTTGGCAAAGGTTGGTCAGGAATTGACCCTTCTAGCCCAGAAAATCTTGG
AGGCAGAGTCAGGTAAGAAGGTACAGGGAAATCTTTTAGACAAGGGGAAAATTACGGCGAGTGAGGATGGGGTGCTTCAT
CTTAATCCTGAGACCAGTGATTCTAGCATGGTTGCAGAAGGTGCCCTACTAGCCCAACTTTATCCATCTTTGGAAAGAGA
AGGGAAAGCCAAACTCACAGCCTATCTAAGTTCAAAAGATGTAGCAAGAATCAAGGTCGGTGATTCTGTTCGCTATACTA
CGACTCATGATGCCGGGAATCAACTTTTCCTAGATTCTACTATTACAAGTATTGATGCGACAGCTACTAAGACTGAGAAA
GGGAATTTCTTTAAAATCGAGGCGGAGACTAATCTAACTTCGGAGCAGGCTGAAAAACTTAGGTACGGGGTGGAAGGCCG
CTTGCAGATGATTACGGGCAAGAAAAGTTATCTACGTTATTATTTGGATCAATTTTTGAACAAAGAGTAA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB Streptococcus pneumoniae TIGR4

99.332

100

0.993
  comB Streptococcus pneumoniae Rx1

99.109

100

0.991
  comB Streptococcus pneumoniae D39

99.109

100

0.991
  comB Streptococcus pneumoniae R6

99.109

100

0.991
  comB Streptococcus mitis SK321

94.878

100

0.949
  comB Streptococcus mitis NCTC 12261

94.432

100

0.944
  comB Streptococcus gordonii str. Challis substr. CH1

55.333

100

0.555

Multiple sequence alignment