Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE   Type   Machinery gene
Locus tag   DV427_RS02100 Genome accession   NZ_CP031240
Coordinates   442691..444028 (-) Length   445 a.a.
NCBI ID   WP_114891148.1    Uniprot ID   -
Organism   Haemophilus haemolyticus strain M19345     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 437691..449028
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DV427_RS02070 - 438520..439293 (-) 774 WP_114891143.1 DeoR/GlpR family DNA-binding transcription regulator -
  DV427_RS02075 - 439422..439694 (-) 273 WP_005634530.1 HU family DNA-binding protein -
  DV427_RS02080 - 439832..440422 (-) 591 WP_114891144.1 YjaG family protein -
  DV427_RS02085 nudC 440455..441252 (-) 798 WP_114891145.1 NAD(+) diphosphatase -
  DV427_RS02090 nfuA 441320..441916 (-) 597 WP_114891146.1 Fe-S biogenesis protein NfuA -
  DV427_RS02095 - 441992..442678 (-) 687 WP_114891147.1 ComF family protein -
  DV427_RS02100 comE 442691..444028 (-) 1338 WP_114891148.1 type IV pilus secretin PilQ family protein Machinery gene
  DV427_RS02105 comD 444038..444451 (-) 414 WP_114891149.1 competence protein Machinery gene
  DV427_RS02110 comC 444448..444969 (-) 522 WP_114891150.1 competence protein ComC Machinery gene
  DV427_RS02115 comB 444966..445475 (-) 510 WP_114891151.1 competence protein B Machinery gene
  DV427_RS02120 comA 445476..446273 (-) 798 WP_114891152.1 pilus assembly protein PilM Machinery gene
  DV427_RS02125 - 446372..448972 (+) 2601 WP_114891153.1 penicillin-binding protein 1A -

Sequence

Protein


Download         Length: 445 a.a.        Molecular weight: 48973.18 Da        Isoelectric Point: 6.8415

>NTDB_id=304460 DV427_RS02100 WP_114891148.1 442691..444028(-) (comE) [Haemophilus haemolyticus strain M19345]
MKKCLLKCGYFLVCFCLPLIVFANPKTDNERFFIRLSQAPLAQTLEQLAFQHDVNLVMDETLEGNISLKLDNIDMPRLLQ
IIARSKKLTLNKDEGIYYLNGGQSGKGQVVGNLSANEPYLVSHTVKLHFAKASELMKSLTTGSGSLLSPAGSITFDDRSN
LLVIQDEPRSVQNIKKLISEMDKPIEQIAIEARIVTITDESLKELGVRWGIFNPTENAVRVAGSLAGNSFENIADNLNVN
FATTTTPAGSIALQVAKINGRLLDLELSALERENNVEIIASPRLLTTNKKSASIKQGTEIPYVVSNTRNDTQSVEFREAV
LGLEVTPHISKDNNILLDLLVSQNSPGSRVAYGQNEVVSIDKQEINTQVFAKDGETIVLGGVFHDTITKSEDKVPVLGDI
PGIKRLFSKESERHQKRELVIFVTPHILRAGETLEALKQKSAGKK

Nucleotide


Download         Length: 1338 bp        

>NTDB_id=304460 DV427_RS02100 WP_114891148.1 442691..444028(-) (comE) [Haemophilus haemolyticus strain M19345]
ATGAAGAAATGTCTTTTAAAGTGCGGTTATTTTTTAGTGTGTTTTTGTTTGCCATTAATCGTTTTTGCTAATCCTAAAAC
AGATAACGAACGTTTTTTTATTCGTTTATCTCAAGCGCCTTTAGCTCAAACACTGGAGCAATTAGCTTTCCAACATGATG
TCAATTTAGTGATGGATGAGACGCTAGAAGGCAATATTTCTTTGAAATTAGATAATATTGATATGCCACGTTTGCTACAA
ATAATCGCTAGAAGTAAGAAGCTTACTTTGAATAAAGATGAGGGTATTTACTATCTGAATGGAGGGCAATCTGGCAAAGG
TCAAGTTGTCGGAAATCTCTCTGCAAATGAACCGTACTTAGTGAGCCATACGGTAAAACTCCATTTTGCTAAAGCCTCTG
AATTAATGAAATCCTTAACCACAGGAAGTGGCTCTTTGCTTTCTCCTGCTGGGAGCATTACCTTTGATGATCGCAGTAAT
TTACTGGTTATTCAGGATGAACCTCGTTCTGTGCAAAATATTAAAAAATTAATTTCTGAAATGGATAAACCTATTGAGCA
GATTGCTATTGAAGCACGTATTGTGACAATTACGGATGAGAGTTTGAAAGAACTTGGCGTTCGGTGGGGGATTTTTAATC
CAACGGAAAATGCTGTGCGTGTAGCAGGTAGCCTCGCAGGCAATAGCTTTGAAAATATTGCGGATAATCTTAATGTAAAT
TTTGCGACAACGACGACACCTGCTGGCTCGATAGCATTACAAGTCGCGAAAATTAATGGGCGATTGCTTGATTTAGAATT
GAGCGCTTTAGAGCGTGAAAATAATGTAGAAATTATCGCAAGTCCTCGCTTACTCACTACCAATAAGAAAAGTGCGAGCA
TTAAACAAGGTACAGAAATTCCTTATGTTGTGAGTAATACTCGTAATGATACGCAATCTGTGGAATTTCGTGAGGCAGTG
CTTGGTTTGGAAGTGACGCCACATATTTCTAAAGATAACAATATTTTGCTTGATTTATTAGTGAGCCAAAACTCACCAGG
TTCAAGAGTCGCTTATGGACAAAACGAGGTGGTTTCTATTGATAAGCAAGAAATTAATACTCAAGTTTTTGCCAAAGATG
GAGAAACCATTGTGCTTGGTGGTGTGTTCCACGATACGATCACAAAAAGCGAAGATAAAGTGCCAGTACTTGGCGATATA
CCTGGCATTAAACGATTGTTTAGTAAAGAAAGTGAACGACATCAAAAACGTGAGCTCGTGATTTTCGTGACACCGCATAT
TTTAAGAGCGGGAGAAACGTTAGAGGCGTTGAAACAAAAAAGTGCAGGCAAAAAATAA

Domains

Predicted by InterproScan.

Bacterial type II/III secretion system short domain (Secretin_N)

(123-187)

Bacterial type II and III secretion system protein (Secretin)

(269-429)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE Haemophilus influenzae Rd KW20

94.157

100

0.942
  comE Haemophilus influenzae 86-028NP

94.157

100

0.942
  comE Glaesserella parasuis strain SC1401

51.529

95.506

0.492
  pilQ Vibrio campbellii strain DS40M4

42.654

94.831

0.404
  pilQ Vibrio cholerae O1 biovar El Tor strain E7946

41.99

92.584

0.389
  pilQ Vibrio cholerae strain A1552

41.99

92.584

0.389

Multiple sequence alignment