Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   DV365_RS01255 Genome accession   NZ_CP031237
Coordinates   239537..240754 (+) Length   405 a.a.
NCBI ID   WP_114890121.1    Uniprot ID   -
Organism   Haemophilus influenzae strain M12125     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 234537..245754
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DV365_RS01235 corC 235499..236398 (-) 900 WP_005656283.1 CNNM family magnesium/cobalt transport protein CorC -
  DV365_RS01240 ampD 237022..237582 (-) 561 WP_005648974.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -
  DV365_RS01245 pilA 237697..238149 (+) 453 WP_114890119.1 prepilin-type N-terminal cleavage/methylation domain-containing protein Machinery gene
  DV365_RS01250 pilB 238146..239540 (+) 1395 WP_114890120.1 GspE/PulE family protein Machinery gene
  DV365_RS01255 pilC 239537..240754 (+) 1218 WP_114890121.1 type II secretion system F family protein Machinery gene
  DV365_RS01260 pilD 240751..241446 (+) 696 WP_114890122.1 A24 family peptidase Machinery gene
  DV365_RS01265 rho 241502..242764 (-) 1263 WP_114890123.1 transcription termination factor Rho -
  DV365_RS01270 metJ 243000..243317 (+) 318 WP_005631186.1 met regulon transcriptional regulator MetJ -
  DV365_RS01275 - 243331..243708 (-) 378 WP_075913212.1 Cu(I)-responsive transcriptional regulator -
  DV365_RS01280 - 243785..243991 (+) 207 WP_015701556.1 heavy-metal-associated domain-containing protein -
  DV365_RS01285 - 244065..244271 (+) 207 WP_015701556.1 heavy-metal-associated domain-containing protein -
  DV365_RS01290 - 244345..244551 (+) 207 WP_005631184.1 heavy-metal-associated domain-containing protein -

Sequence

Protein


Download         Length: 405 a.a.        Molecular weight: 46119.29 Da        Isoelectric Point: 9.4766

>NTDB_id=304359 DV365_RS01255 WP_114890121.1 239537..240754(+) (pilC) [Haemophilus influenzae strain M12125]
MTKKLFYYQGSNALNQKQKGSIIADTKQQAHFQLISHGLTHIKLQQNWQFGAKPKNSEISELLNQLATLLQSAIPLKNSL
QILQQNCTQIMLNEWLERLLQSIESGLAFSQAIEQQGKYLTQQEIQLIQVGEMTGKLAVVCKKIATHRSQSLALQSKLQK
IMLYPSMVLGISLLLTLALLLFIVPQFAEMYSGNNAELPTITAILLSISNFLKQKISILLFFAFSFFLFYYFYLKRQIWF
HQQKNQLISVMPIFGTIQKLSRLVNFSQSLQIMLQAGIPLNQALDSFLPRTQTWQTKTLVNDIVLDKEVRSILQWVSQGY
AFSDSVSSDLFPMEAQQMLQIGEQSGKLALMLEHIADNYQEKLNHQIDLLSQMLEPLMMVIIGSLIGIIMMGMYLPIFNM
GSVIQ

Nucleotide


Download         Length: 1218 bp        

>NTDB_id=304359 DV365_RS01255 WP_114890121.1 239537..240754(+) (pilC) [Haemophilus influenzae strain M12125]
ATGACTAAAAAACTCTTTTATTATCAAGGTAGTAACGCATTAAATCAGAAACAAAAAGGCTCAATTATTGCGGATACGAA
ACAACAAGCACACTTTCAGTTAATAAGCCACGGGCTTACTCACATCAAATTACAACAAAACTGGCAATTTGGGGCAAAAC
CCAAAAATTCAGAAATCAGTGAATTACTCAATCAATTAGCGACATTGCTACAGTCCGCAATTCCGTTAAAAAACAGTCTG
CAAATTTTGCAACAAAATTGTACTCAAATTATGCTCAACGAATGGCTTGAACGGCTGCTTCAATCCATTGAATCTGGCTT
AGCATTCTCACAAGCAATTGAACAACAAGGAAAATATCTCACACAACAAGAAATTCAACTGATTCAAGTGGGAGAAATGA
CAGGAAAACTTGCCGTAGTTTGTAAAAAAATAGCCACGCACCGTAGTCAATCTTTGGCTTTACAAAGCAAATTACAGAAA
ATTATGTTATATCCCTCAATGGTATTGGGAATTTCTCTATTATTGACACTCGCATTACTGCTTTTTATCGTGCCTCAATT
TGCTGAAATGTACAGTGGCAATAATGCCGAATTACCAACAATAACCGCAATATTGCTCTCTATATCCAATTTTCTTAAGC
AAAAGATTAGCATTTTGCTATTTTTCGCTTTTAGTTTTTTTCTATTTTATTACTTCTATCTAAAACGCCAGATCTGGTTT
CATCAACAGAAAAACCAACTTATCTCTGTCATGCCTATTTTTGGCACAATTCAAAAACTTTCACGTTTAGTGAACTTTAG
TCAAAGTTTACAAATTATGTTACAGGCTGGCATTCCGCTTAATCAAGCACTAGACAGTTTTCTTCCTCGCACACAAACGT
GGCAAACCAAGACGCTTGTAAATGACATCGTATTAGATAAAGAAGTGCGGTCAATTTTACAATGGGTTTCTCAAGGCTAT
GCGTTTTCTGATAGTGTAAGTAGCGATCTTTTCCCGATGGAAGCACAACAAATGCTCCAAATTGGCGAGCAAAGCGGAAA
ACTCGCTTTGATGCTAGAGCATATTGCGGATAATTACCAAGAAAAACTTAATCATCAAATTGACTTGCTCTCACAAATGC
TAGAACCATTAATGATGGTGATCATCGGCAGTCTGATTGGGATTATTATGATGGGAATGTATTTACCTATCTTTAATATG
GGCTCTGTTATTCAATGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(266-396)

Type II secretion system (T2SS), protein F (T2SSF)

(63-185)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Haemophilus influenzae 86-028NP

95.813

100

0.96
  pilC Haemophilus influenzae Rd KW20

95.567

100

0.958
  pilC Glaesserella parasuis strain SC1401

39.25

98.765

0.388

Multiple sequence alignment