Detailed information NTG0304316

Bioinformatically predicted

Overview

• Name: comE
• Type: Machinery gene
• Locus tag: DV400_RS01015
• Genome accession: NZ_CP031236
• Coordinates: 198398..199741 (-)
• Length: 447 a.a.
• NCBI ID: WP_050948867.1
• Uniprot ID: -
• Organism: Haemophilus influenzae strain M25267
• Function: type IV pilus biogenesis and function (predicted from homology) DNA binding and uptake

Genomic Context

Location: 193398..204741

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DV400_RS00985	-	194330..194602 (-)	273	WP_005630954.1	HU family DNA-binding protein	-
DV400_RS00990	-	194741..195331 (-)	591	WP_021034387.1	YjaG family protein	-
DV400_RS00995	nudC	195367..196161 (-)	795	WP_021034386.1	NAD(+) diphosphatase	-
DV400_RS01000	nfuA	196229..196825 (-)	597	WP_021034385.1	Fe-S biogenesis protein NfuA	-
DV400_RS01005	-	196901..197587 (-)	687	WP_050948865.1	ComF family protein	-
DV400_RS01010	tnpA	197946..198401 (-)	456	WP_050948866.1	IS200/IS605 family transposase	-
DV400_RS01015	comE	198398..199741 (-)	1344	WP_050948867.1	type IV pilus secretin PilQ	Machinery gene
DV400_RS01020	-	199751..200165 (-)	415	Protein_198	pilus assembly protein PilP	-
DV400_RS01025	comC	200162..200683 (-)	522	WP_050948869.1	competence protein ComC	Machinery gene
DV400_RS01030	comB	200680..201189 (-)	510	WP_050948870.1	hypothetical protein	Machinery gene
DV400_RS01035	comA	201190..201987 (-)	798	WP_050948871.1	pilus assembly protein PilM	Machinery gene
DV400_RS01040	-	202086..204686 (+)	2601	WP_050948872.1	penicillin-binding protein 1A	-

Sequence

Protein

• Length: 447 a.a.
• Molecular weight: 49341.57 Da
• Isoelectric Point: 6.8467

>NTDB_id=304316 DV400_RS01015 WP_050948867.1 198398..199741(-) (comE) [Haemophilus influenzae strain M25267]
MKKYFLKCGYFLVCFCLPLIVFANPKTDNERFFIRLSQAPLAQTLEQLAFQQDVNLVMDEALESNISLRLDNIDMPRLLQ
IIAKSKKLTLNKDEGIYYLNGGQSGKGQVAGNLTTNEPHLMSHTVKLHFAKASELMKSLTTGSGSLLSSAGSITFDDRSN
LLVIQDEPRSVQNIKKLIAEMDKPIEQIAIEARIVTITDESLKELGVRWGIFNPTENAARVAGSLSGNSFENIADNLNVN
FATTTTPAGSIALQVAKINGRLLDLELSALERENNVEIIASPRLLTTNKKSASIKQGTEIPYIVSNTRNDTQSVEFREAV
LGLEVTPHISKDNNILLDLLVSQNSPGSRVSYGQNEVVSIDKQEINTQVFAKDGETIVLGGVFHDTITKSEDKVPLLGDI
PVIKRLFSKESERHQKRELVIFVTPHILKAGETLEALKQKSAGKKLQ

Nucleotide

• Length: 1344 bp

>NTDB_id=304316 DV400_RS01015 WP_050948867.1 198398..199741(-) (comE) [Haemophilus influenzae strain M25267]
ATGAAGAAATATTTTTTAAAGTGCGGTTATTTTTTAGTCTGTTTTTGTTTGCCATTAATCGTTTTTGCTAATCCCAAAAC
TGATAACGAACGTTTTTTTATTCGTTTATCGCAAGCACCTTTAGCCCAAACATTGGAACAGTTGGCTTTTCAACAAGATG
TGAATTTAGTGATGGATGAAGCATTAGAAAGTAATATTTCATTGAGATTAGATAATATTGATATGCCACGTTTACTACAA
ATAATCGCTAAAAGTAAGAAGCTTACTTTGAATAAAGATGAGGGTATTTACTATCTGAATGGAGGGCAATCAGGCAAAGG
GCAAGTTGCAGGAAATCTTACTACAAATGAACCGCACTTAATGAGTCACACGGTAAAACTCCATTTTGCTAAAGCCTCTG
AATTAATGAAGTCCTTAACGACAGGAAGTGGCTCTTTGCTTTCATCAGCTGGGAGCATTACCTTTGATGATCGTAGTAAT
TTGCTCGTGATTCAAGATGAACCTCGTTCTGTGCAAAATATTAAAAAACTAATTGCTGAAATGGATAAACCTATTGAGCA
GATCGCTATTGAAGCGCGTATTGTGACAATTACGGACGAAAGTTTGAAAGAACTTGGCGTTCGGTGGGGGATTTTTAATC
CAACGGAAAATGCTGCGCGTGTAGCGGGCAGCTTATCCGGCAATAGCTTTGAAAATATTGCGGATAATCTTAATGTAAAT
TTTGCGACAACGACGACACCTGCTGGCTCGATAGCATTACAAGTCGCGAAAATTAATGGTCGATTGCTCGATTTAGAATT
AAGCGCGTTAGAGCGTGAAAATAATGTGGAAATTATCGCAAGCCCTCGCTTACTAACCACAAATAAGAAAAGTGCAAGCA
TTAAACAGGGGACAGAAATTCCTTATATTGTGAGCAATACTCGTAACGATACGCAATCTGTGGAATTTCGCGAGGCGGTG
CTTGGTTTGGAAGTCACACCACATATTTCTAAAGATAACAATATTTTACTTGATTTATTAGTGAGCCAAAACTCACCAGG
TTCTCGTGTTTCTTATGGACAAAATGAGGTGGTTTCTATTGATAAGCAAGAAATTAATACTCAGGTTTTTGCCAAAGATG
GGGAAACCATTGTGCTTGGCGGCGTGTTTCACGACACAATTACGAAAAGCGAAGATAAGGTGCCATTGCTTGGCGATATA
CCCGTTATTAAACGATTATTCAGCAAAGAAAGCGAACGACATCAAAAACGTGAGTTAGTGATTTTTGTCACGCCGCATAT
TTTAAAAGCAGGAGAAACGTTAGAGGCGTTGAAGCAAAAAAGTGCGGGGAAAAAGTTACAATGA

Domains

Predicted by InterproScan.

• Bacterial type II/III secretion system short domain (Secretin_N) (123-187)

• Bacterial type II and III secretion system protein (Secretin) (269-429)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comE	Haemophilus influenzae 86-028NP	96.404	99.553	0.96
comE	Haemophilus influenzae Rd KW20	96.18	99.553	0.957
comE	Glaesserella parasuis strain SC1401	52.706	95.078	0.501
pilQ	Vibrio campbellii strain DS40M4	42.959	93.736	0.403
pilQ	Vibrio cholerae O1 biovar El Tor strain E7946	42.233	92.17	0.389
pilQ	Vibrio cholerae strain A1552	42.233	92.17	0.389