Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE1/comEA   Type   Machinery gene
Locus tag   HSM_RS10365 Genome accession   NC_010519
Coordinates   2255899..2256234 (-) Length   111 a.a.
NCBI ID   WP_012341067.1    Uniprot ID   A0A9Q7E5D2
Organism   Histophilus somni 2336     
Function   dsDNA binding (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2250899..2261234
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HSM_RS10345 (HSM_2007) serA 2251922..2253154 (-) 1233 WP_012341062.1 phosphoglycerate dehydrogenase -
  HSM_RS10350 (HSM_2008) rpiA 2253180..2253839 (-) 660 WP_012341063.1 ribose-5-phosphate isomerase RpiA -
  HSM_RS10355 (HSM_2009) hemW 2253935..2255113 (-) 1179 WP_012341064.1 radical SAM family heme chaperone HemW -
  HSM_RS10360 (HSM_2010) rdgB 2255113..2255709 (-) 597 WP_012341066.1 RdgB/HAM1 family non-canonical purine NTP pyrophosphatase -
  HSM_RS10365 (HSM_2011) comE1/comEA 2255899..2256234 (-) 336 WP_012341067.1 helix-hairpin-helix domain-containing protein Machinery gene
  HSM_RS10370 (HSM_2012) - 2256456..2256845 (-) 390 WP_012341068.1 RidA family protein -
  HSM_RS10375 (HSM_2013) - 2256906..2257487 (-) 582 WP_012341069.1 aminotransferase class IV family protein -
  HSM_RS10380 (HSM_2014) - 2257636..2258643 (-) 1008 WP_012341070.1 aminodeoxychorismate synthase component I -
  HSM_RS10385 (HSM_2015) - 2258700..2259269 (+) 570 WP_012341071.1 anthranilate synthase component II -
  HSM_RS10390 (HSM_2016) - 2259422..2259901 (+) 480 WP_011608283.1 Dps family protein -

Sequence

Protein


Download         Length: 111 a.a.        Molecular weight: 12138.14 Da        Isoelectric Point: 10.2041

>NTDB_id=30411 HSM_RS10365 WP_012341067.1 2255899..2256234(-) (comE1/comEA) [Histophilus somni 2336]
MKKITSFFKSLLMLSVALGAFNAFAETPTQPPSSAQATQQVEPVIISDKLNINTATAEEIKHALIGIGSKKAEAIVQYRE
KFGKFTAAEQLLEVKGIGKATLEKNRDRIIF

Nucleotide


Download         Length: 336 bp        

>NTDB_id=30411 HSM_RS10365 WP_012341067.1 2255899..2256234(-) (comE1/comEA) [Histophilus somni 2336]
ATGAAAAAAATAACCTCATTTTTCAAATCATTATTGATGTTAAGTGTTGCTTTGGGTGCTTTTAATGCATTTGCAGAAAC
ACCAACTCAACCACCTAGTTCAGCCCAAGCAACACAACAAGTTGAACCGGTCATTATTAGCGATAAATTGAACATCAATA
CTGCAACAGCGGAAGAAATTAAACACGCTTTAATAGGAATTGGAAGCAAAAAAGCCGAGGCAATTGTTCAATATCGTGAA
AAATTTGGTAAATTTACCGCGGCTGAACAGTTACTTGAAGTCAAGGGGATTGGCAAAGCAACACTAGAAAAAAATAGAGA
TCGCATCATTTTCTAG

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(49-109)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE1/comEA Haemophilus influenzae Rd KW20

60.36

100

0.604
  comEA/comE1 Glaesserella parasuis strain SC1401

53.333

100

0.577
  comEA Vibrio cholerae C6706

44.954

98.198

0.441
  comEA Vibrio cholerae strain A1552

44.954

98.198

0.441
  comEA Vibrio campbellii strain DS40M4

43.269

93.694

0.405

Multiple sequence alignment