Detailed information    

insolico Bioinformatically predicted

Overview

Name   radC   Type   Machinery gene
Locus tag   ETT46_RS04565 Genome accession   NZ_CP035453
Coordinates   871846..872526 (+) Length   226 a.a.
NCBI ID   WP_002984709.1    Uniprot ID   A2REK0
Organism   Streptococcus pyogenes strain emm100     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 866846..877526
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ETT46_RS04545 (ETT46_04540) aphA 867272..868003 (+) 732 WP_136264936.1 acid phosphatase AphA -
  ETT46_RS04550 (ETT46_04545) - 868181..869713 (+) 1533 WP_002995354.1 ClC family H(+)/Cl(-) exchange transporter -
  ETT46_RS04555 (ETT46_04550) - 869876..870490 (+) 615 WP_011017748.1 SGNH/GDSL hydrolase family protein -
  ETT46_RS04560 (ETT46_04555) - 870670..871797 (+) 1128 WP_002994399.1 AI-2E family transporter -
  ETT46_RS04565 (ETT46_04560) radC 871846..872526 (+) 681 WP_002984709.1 DNA repair protein RadC Machinery gene
  ETT46_RS04570 (ETT46_04565) - 872528..873223 (-) 696 WP_002989835.1 gamma-glutamyl-gamma-aminobutyrate hydrolase family protein -
  ETT46_RS04575 (ETT46_04570) - 873233..873877 (-) 645 WP_002984705.1 redox-sensing transcriptional repressor Rex -
  ETT46_RS04580 (ETT46_04575) - 874129..874476 (-) 348 WP_002989831.1 DUF1831 domain-containing protein -
  ETT46_RS04585 (ETT46_04580) - 874466..875593 (-) 1128 WP_136264938.1 cysteine desulfurase family protein -
  ETT46_RS04590 (ETT46_04585) - 875590..876570 (-) 981 WP_002989827.1 ribose-phosphate diphosphokinase -
  ETT46_RS04595 (ETT46_04590) - 876710..877288 (-) 579 WP_002989824.1 CYTH domain-containing protein -

Sequence

Protein


Download         Length: 226 a.a.        Molecular weight: 25742.96 Da        Isoelectric Point: 7.3866

>NTDB_id=303362 ETT46_RS04565 WP_002984709.1 871846..872526(+) (radC) [Streptococcus pyogenes strain emm100]
MYSIKCDDNKAMPRERLMRLGAESLSNQELLAILLRTGNKEKHVLELSSYLLSHLDSLADFKKMSLQELQHLAGIGKVKA
IEIKAMIELVSRILATDKTLTDSVLTSVQVAEKMMAALGDKKQEHLVVLYLDNQNRIIEEKTIFIGTVRRSLAEPREILY
YACKNMATSLIVIHNHPSGNIEPSSNDYCFTEKIKRSCEDLGIICLDHIIVSYKDYYSFREKSTLF

Nucleotide


Download         Length: 681 bp        

>NTDB_id=303362 ETT46_RS04565 WP_002984709.1 871846..872526(+) (radC) [Streptococcus pyogenes strain emm100]
ATGTATTCTATAAAATGTGATGATAATAAAGCCATGCCAAGAGAACGTTTGATGCGACTAGGAGCAGAGTCTCTAAGTAA
TCAAGAATTATTAGCAATTTTATTACGAACAGGTAATAAAGAAAAGCATGTCTTAGAGCTGTCATCCTATCTTTTATCGC
ATTTAGACAGTCTGGCAGATTTTAAAAAGATGTCTTTGCAAGAATTACAACATTTGGCAGGTATAGGAAAAGTTAAAGCG
ATTGAAATTAAAGCTATGATTGAGTTGGTTTCCCGAATTTTAGCGACCGATAAGACATTAACTGATAGCGTATTAACCAG
TGTTCAGGTCGCTGAAAAAATGATGGCAGCTTTAGGAGATAAAAAACAAGAGCATTTAGTCGTATTGTATTTAGATAATC
AAAATCGTATTATTGAAGAAAAAACTATTTTTATTGGGACTGTCCGACGTTCACTTGCAGAACCAAGAGAAATTTTATAC
TATGCCTGTAAAAATATGGCGACTAGTCTCATTGTTATTCATAATCATCCTTCAGGAAATATTGAACCTAGTTCTAACGA
TTATTGCTTTACTGAAAAAATAAAACGATCATGTGAAGATTTAGGCATTATCTGTCTAGATCACATTATCGTTAGCTATA
AAGATTATTATAGTTTTCGAGAAAAATCAACCCTTTTTTAA

Domains

Predicted by InterProScan.

RadC-like JAB domain (RadC)

(107-222)

UPF0758 N-terminal (UPF0758_N)

(10-81)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A2REK0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  radC Streptococcus pneumoniae TIGR4

57.965

100

0.58
  radC Streptococcus pneumoniae R6

57.522

100

0.575
  radC Streptococcus pneumoniae D39

57.522

100

0.575
  radC Streptococcus gordonii str. Challis substr. CH1

55.752

100

0.558
  ysxA/radC Bacillus subtilis subsp. subtilis str. 168

43.119

96.46

0.416
  radC Haemophilus influenzae Rd KW20

37.9

96.903

0.367