Detailed information
Bioinformatically predicted
Overview
| Name | comA | Type | Regulator |
| Locus tag | DT351_RS07870 | Genome accession | NZ_CP031003 |
| Coordinates | 1498356..1500512 (-) | Length | 718 a.a. |
| NCBI ID | WP_116843679.1 | Uniprot ID | A0A385AFB1 |
| Organism | Latilactobacillus curvatus strain TMW 1.1928 | ||
| Function | processing and transport of ComC (predicted from homology) Competence regulation |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| Prophage | 1479521..1508927 | 1498356..1500512 | within | 0 |
| IScluster/Tn | 1500816..1503883 | 1498356..1500512 | flank | 304 |
Gene organization within MGE regions
Location: 1479521..1508927
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| DT351_RS07740 (DT351_07740) | - | 1479521..1479832 (-) | 312 | WP_162875349.1 | ArpU family phage packaging/lysis transcriptional regulator | - |
| DT351_RS07745 (DT351_07745) | - | 1479867..1480286 (-) | 420 | WP_076786405.1 | ArpU family phage packaging/lysis transcriptional regulator | - |
| DT351_RS07750 (DT351_07750) | - | 1480539..1480868 (+) | 330 | Protein_1512 | integrase core domain-containing protein | - |
| DT351_RS07755 (DT351_07755) | - | 1480965..1481216 (-) | 252 | WP_116843666.1 | Arm DNA-binding domain-containing protein | - |
| DT351_RS07760 (DT351_07760) | - | 1481436..1482290 (-) | 855 | WP_162875350.1 | hypothetical protein | - |
| DT351_RS07765 (DT351_07765) | - | 1482283..1483643 (+) | 1361 | WP_116843668.1 | IS3 family transposase | - |
| DT351_RS11435 | - | 1483652..1483822 (-) | 171 | WP_162875351.1 | hypothetical protein | - |
| DT351_RS07770 (DT351_07770) | - | 1483968..1484528 (-) | 561 | WP_116843669.1 | DUF4352 domain-containing protein | - |
| DT351_RS07775 (DT351_07775) | - | 1484623..1485183 (-) | 561 | WP_116843670.1 | Ltp family lipoprotein | - |
| DT351_RS07785 (DT351_07785) | - | 1485666..1486004 (+) | 339 | Protein_1519 | IS30 family transposase | - |
| DT351_RS07790 (DT351_07790) | - | 1486237..1487157 (-) | 921 | WP_011373852.1 | IS30-like element ISLsa1 family transposase | - |
| DT351_RS07795 (DT351_07795) | - | 1487283..1487675 (-) | 393 | WP_116843671.1 | hypothetical protein | - |
| DT351_RS07800 (DT351_07800) | - | 1487821..1488752 (-) | 932 | Protein_1522 | IS30-like element ISLpl1 family transposase | - |
| DT351_RS07810 (DT351_07810) | - | 1489137..1490918 (+) | 1782 | WP_116843673.1 | glycerophosphodiester phosphodiesterase | - |
| DT351_RS07815 (DT351_07815) | - | 1490974..1491249 (-) | 276 | WP_004271077.1 | hypothetical protein | - |
| DT351_RS07820 (DT351_07820) | - | 1491325..1492680 (-) | 1356 | WP_116843674.1 | FAD-dependent oxidoreductase | - |
| DT351_RS07825 (DT351_07825) | - | 1492827..1493267 (+) | 441 | WP_240327062.1 | hypothetical protein | - |
| DT351_RS07830 (DT351_07830) | - | 1493315..1493935 (+) | 621 | WP_116843676.1 | endonuclease III | - |
| DT351_RS07835 (DT351_07835) | tdcB | 1493973..1495013 (-) | 1041 | WP_116843677.1 | bifunctional threonine ammonia-lyase/L-serine ammonia-lyase TdcB | - |
| DT351_RS07840 (DT351_07840) | - | 1495229..1495561 (+) | 333 | WP_004271076.1 | hypothetical protein | - |
| DT351_RS07845 (DT351_07845) | - | 1495607..1495804 (-) | 198 | WP_004271075.1 | hypothetical protein | - |
| DT351_RS07850 (DT351_07850) | - | 1495905..1496231 (-) | 327 | WP_004271083.1 | bacteriocin immunity protein | - |
| DT351_RS07860 (DT351_07860) | - | 1496559..1496762 (-) | 204 | WP_076790047.1 | Blp family class II bacteriocin | - |
| DT351_RS07865 (DT351_07865) | - | 1496965..1498341 (-) | 1377 | WP_099947277.1 | HlyD family secretion protein | - |
| DT351_RS07870 (DT351_07870) | comA | 1498356..1500512 (-) | 2157 | WP_116843679.1 | peptide cleavage/export ABC transporter | Regulator |
| DT351_RS07875 (DT351_07875) | - | 1500816..1501885 (+) | 1070 | WP_112234043.1 | IS3-like element IS1163 family transposase | - |
| DT351_RS07880 (DT351_07880) | - | 1502046..1502342 (-) | 297 | WP_076787949.1 | bacteriocin immunity protein | - |
| DT351_RS07885 (DT351_07885) | - | 1502436..1502621 (-) | 186 | WP_056946897.1 | leucocin A/sakacin P family class II bacteriocin | - |
| DT351_RS07895 (DT351_07895) | - | 1503948..1504697 (-) | 750 | WP_116843680.1 | response regulator transcription factor | - |
| DT351_RS07900 (DT351_07900) | - | 1504699..1505865 (-) | 1167 | WP_035187109.1 | GHKL domain-containing protein | - |
| DT351_RS07905 (DT351_07905) | - | 1506064..1506177 (-) | 114 | WP_004271310.1 | bacteriocin | - |
| DT351_RS07910 (DT351_07910) | - | 1506352..1507404 (-) | 1053 | WP_089541951.1 | IS30 family transposase | - |
| DT351_RS07915 (DT351_07915) | - | 1507621..1507875 (-) | 255 | WP_004271311.1 | hypothetical protein | - |
| DT351_RS07920 (DT351_07920) | - | 1508091..1508438 (+) | 348 | WP_054644151.1 | bacteriocin immunity protein | - |
| DT351_RS07925 (DT351_07925) | - | 1508637..1508927 (-) | 291 | WP_004265964.1 | hypothetical protein | - |
Sequence
Protein
Download Length: 718 a.a. Molecular weight: 80204.37 Da Isoelectric Point: 5.8513
>NTDB_id=302782 DT351_RS07870 WP_116843679.1 1498356..1500512(-) (comA) [Latilactobacillus curvatus strain TMW 1.1928]
MIDRKIYIPQVDEMDCGVAALAMILKHYGSSASLAYLRNEAKTDLEGTTALGLVKTAENLGFETKAIQADMSLFEVADLP
FPFIAHVLKNGELLHYYVVLGIKKDAIIIADPDPTVGIAKMTQSQFKSEWTGVALFIAPKPSYQPVKQQTKASLFSFVPT
LMQQKRLVINITLAALLITIISILGSYFLQTVIDTYIPNNMQSTLAIVAIGLIIFYGFQSIFTYAQNFLLAVLGQRLSIE
IILSYLRHVFELPMSFFATRKTGEIISRFNDANKIIDALASAIISIFLDITVVVIMGIILIIQNTTLFWLTLAVIPIYIA
VITLFAKPFEKLNQKEMESNAVLNSAIIEDLHGIETIKALTSESERYQKIDTAFVDYLKKSFDYVKADTLQQAIKLFVQL
GLNVFVLWVGAILVTHNELSIGQLMTYNALLAYFVNPLQNIINLQTKLQSARVANNRLNEVYLVDSEFKTERPIKSESQL
VGPIELQNVSYQYGYGQRVLESISLKIEPNEKLTIVGMSGSGKSTLVKLLVNFFEPTEGKVLFNQQDTQTIDKKTLRQFV
NYIAQTPYIFSGSIWDNLKLGNRPGITQADIMHACELAEIKNDIEKMPLQFETLLDEDGNTLSGGQKQRLTIARALLSPA
RVLIFDESTSGLDTITEGLLVDHLMALEERTIIFIAHRLAIAKKTNNILVLENGSVVETGTHDALVDTQGRYYQLLNH
MIDRKIYIPQVDEMDCGVAALAMILKHYGSSASLAYLRNEAKTDLEGTTALGLVKTAENLGFETKAIQADMSLFEVADLP
FPFIAHVLKNGELLHYYVVLGIKKDAIIIADPDPTVGIAKMTQSQFKSEWTGVALFIAPKPSYQPVKQQTKASLFSFVPT
LMQQKRLVINITLAALLITIISILGSYFLQTVIDTYIPNNMQSTLAIVAIGLIIFYGFQSIFTYAQNFLLAVLGQRLSIE
IILSYLRHVFELPMSFFATRKTGEIISRFNDANKIIDALASAIISIFLDITVVVIMGIILIIQNTTLFWLTLAVIPIYIA
VITLFAKPFEKLNQKEMESNAVLNSAIIEDLHGIETIKALTSESERYQKIDTAFVDYLKKSFDYVKADTLQQAIKLFVQL
GLNVFVLWVGAILVTHNELSIGQLMTYNALLAYFVNPLQNIINLQTKLQSARVANNRLNEVYLVDSEFKTERPIKSESQL
VGPIELQNVSYQYGYGQRVLESISLKIEPNEKLTIVGMSGSGKSTLVKLLVNFFEPTEGKVLFNQQDTQTIDKKTLRQFV
NYIAQTPYIFSGSIWDNLKLGNRPGITQADIMHACELAEIKNDIEKMPLQFETLLDEDGNTLSGGQKQRLTIARALLSPA
RVLIFDESTSGLDTITEGLLVDHLMALEERTIIFIAHRLAIAKKTNNILVLENGSVVETGTHDALVDTQGRYYQLLNH
Nucleotide
Download Length: 2157 bp
>NTDB_id=302782 DT351_RS07870 WP_116843679.1 1498356..1500512(-) (comA) [Latilactobacillus curvatus strain TMW 1.1928]
ATGATAGATCGTAAAATTTATATACCACAAGTAGATGAAATGGATTGTGGCGTAGCAGCCTTAGCGATGATTCTTAAACA
TTATGGTTCTTCAGCTTCGCTGGCTTATTTACGTAATGAGGCTAAAACTGATTTAGAAGGAACAACGGCGCTTGGACTAG
TGAAGACAGCTGAGAATTTAGGTTTCGAAACGAAGGCGATTCAAGCTGATATGAGTTTGTTTGAAGTCGCAGATTTACCA
TTTCCTTTTATTGCACATGTTCTAAAAAATGGCGAGCTATTACATTATTATGTTGTACTAGGGATAAAAAAAGATGCCAT
TATAATCGCCGATCCTGATCCAACAGTGGGCATCGCTAAGATGACGCAATCACAGTTTAAATCGGAATGGACGGGCGTTG
CATTATTTATTGCTCCAAAACCGAGCTATCAACCAGTTAAGCAGCAAACAAAAGCGAGTTTATTTTCATTTGTTCCAACT
TTGATGCAGCAAAAGCGATTGGTAATTAATATTACTTTGGCGGCGCTACTCATAACCATTATTAGTATTCTAGGATCTTA
TTTCTTACAGACTGTCATTGATACCTATATCCCAAATAACATGCAGAGCACGCTGGCGATTGTTGCAATTGGTTTAATTA
TCTTTTATGGCTTCCAGTCAATCTTTACATATGCTCAAAATTTTTTATTGGCGGTTTTAGGACAGCGGTTATCAATTGAG
ATTATTTTAAGTTACTTAAGACATGTTTTTGAATTACCAATGTCTTTTTTTGCAACACGTAAAACAGGTGAAATAATTTC
ACGATTTAATGACGCGAATAAAATTATTGATGCGCTAGCAAGCGCAATTATTTCAATTTTTTTAGATATTACAGTCGTTG
TTATTATGGGGATTATTCTGATCATTCAAAATACAACTTTATTCTGGTTAACCTTAGCAGTGATTCCAATCTATATTGCC
GTGATTACTTTATTTGCAAAACCTTTTGAAAAATTAAATCAAAAGGAAATGGAAAGTAATGCAGTATTGAATTCGGCGAT
CATTGAAGATTTACATGGCATTGAAACGATTAAAGCGTTAACTAGTGAAAGTGAACGATATCAAAAAATAGATACAGCAT
TTGTTGATTATCTGAAGAAGAGTTTTGACTATGTAAAAGCTGATACATTGCAACAAGCAATTAAGTTGTTTGTCCAATTA
GGGCTGAATGTCTTTGTGCTGTGGGTAGGCGCTATTTTAGTCACGCATAACGAGTTATCAATTGGGCAATTGATGACCTA
CAATGCCTTGCTGGCGTATTTTGTAAATCCGTTACAGAATATCATCAATTTACAGACTAAGTTACAGAGCGCGAGGGTAG
CCAATAATCGGTTGAATGAAGTTTATCTGGTTGATTCTGAGTTCAAGACAGAACGACCAATTAAATCCGAGTCACAGTTG
GTAGGCCCAATTGAGTTACAAAATGTGAGTTACCAATATGGTTATGGGCAGAGAGTGCTTGAATCGATTAGTTTAAAGAT
TGAGCCGAATGAAAAATTAACAATTGTGGGCATGAGCGGTTCGGGGAAATCAACATTGGTTAAGTTACTCGTTAATTTTT
TTGAACCAACGGAGGGAAAGGTTCTTTTTAATCAACAAGATACACAGACAATTGATAAAAAGACATTGCGGCAGTTTGTT
AACTATATTGCACAGACACCGTACATTTTCTCAGGAAGTATTTGGGATAATCTTAAGTTAGGTAATCGGCCAGGAATCAC
ACAAGCGGACATCATGCATGCGTGTGAGCTAGCAGAGATAAAGAATGATATTGAAAAAATGCCGCTCCAATTTGAAACAT
TATTGGATGAAGATGGAAACACATTGTCAGGTGGTCAAAAACAGCGATTAACAATTGCGCGAGCACTATTATCACCAGCT
CGGGTACTAATTTTTGATGAGTCTACTAGTGGGTTAGATACGATAACAGAGGGGCTATTAGTTGATCATCTAATGGCGTT
AGAAGAAAGAACAATCATTTTCATAGCGCATCGTTTAGCGATTGCTAAGAAAACGAACAATATTCTTGTTTTAGAAAATG
GTAGTGTTGTTGAAACTGGGACACATGATGCGTTGGTGGATACACAAGGGCGATATTACCAATTGCTCAATCATTAG
ATGATAGATCGTAAAATTTATATACCACAAGTAGATGAAATGGATTGTGGCGTAGCAGCCTTAGCGATGATTCTTAAACA
TTATGGTTCTTCAGCTTCGCTGGCTTATTTACGTAATGAGGCTAAAACTGATTTAGAAGGAACAACGGCGCTTGGACTAG
TGAAGACAGCTGAGAATTTAGGTTTCGAAACGAAGGCGATTCAAGCTGATATGAGTTTGTTTGAAGTCGCAGATTTACCA
TTTCCTTTTATTGCACATGTTCTAAAAAATGGCGAGCTATTACATTATTATGTTGTACTAGGGATAAAAAAAGATGCCAT
TATAATCGCCGATCCTGATCCAACAGTGGGCATCGCTAAGATGACGCAATCACAGTTTAAATCGGAATGGACGGGCGTTG
CATTATTTATTGCTCCAAAACCGAGCTATCAACCAGTTAAGCAGCAAACAAAAGCGAGTTTATTTTCATTTGTTCCAACT
TTGATGCAGCAAAAGCGATTGGTAATTAATATTACTTTGGCGGCGCTACTCATAACCATTATTAGTATTCTAGGATCTTA
TTTCTTACAGACTGTCATTGATACCTATATCCCAAATAACATGCAGAGCACGCTGGCGATTGTTGCAATTGGTTTAATTA
TCTTTTATGGCTTCCAGTCAATCTTTACATATGCTCAAAATTTTTTATTGGCGGTTTTAGGACAGCGGTTATCAATTGAG
ATTATTTTAAGTTACTTAAGACATGTTTTTGAATTACCAATGTCTTTTTTTGCAACACGTAAAACAGGTGAAATAATTTC
ACGATTTAATGACGCGAATAAAATTATTGATGCGCTAGCAAGCGCAATTATTTCAATTTTTTTAGATATTACAGTCGTTG
TTATTATGGGGATTATTCTGATCATTCAAAATACAACTTTATTCTGGTTAACCTTAGCAGTGATTCCAATCTATATTGCC
GTGATTACTTTATTTGCAAAACCTTTTGAAAAATTAAATCAAAAGGAAATGGAAAGTAATGCAGTATTGAATTCGGCGAT
CATTGAAGATTTACATGGCATTGAAACGATTAAAGCGTTAACTAGTGAAAGTGAACGATATCAAAAAATAGATACAGCAT
TTGTTGATTATCTGAAGAAGAGTTTTGACTATGTAAAAGCTGATACATTGCAACAAGCAATTAAGTTGTTTGTCCAATTA
GGGCTGAATGTCTTTGTGCTGTGGGTAGGCGCTATTTTAGTCACGCATAACGAGTTATCAATTGGGCAATTGATGACCTA
CAATGCCTTGCTGGCGTATTTTGTAAATCCGTTACAGAATATCATCAATTTACAGACTAAGTTACAGAGCGCGAGGGTAG
CCAATAATCGGTTGAATGAAGTTTATCTGGTTGATTCTGAGTTCAAGACAGAACGACCAATTAAATCCGAGTCACAGTTG
GTAGGCCCAATTGAGTTACAAAATGTGAGTTACCAATATGGTTATGGGCAGAGAGTGCTTGAATCGATTAGTTTAAAGAT
TGAGCCGAATGAAAAATTAACAATTGTGGGCATGAGCGGTTCGGGGAAATCAACATTGGTTAAGTTACTCGTTAATTTTT
TTGAACCAACGGAGGGAAAGGTTCTTTTTAATCAACAAGATACACAGACAATTGATAAAAAGACATTGCGGCAGTTTGTT
AACTATATTGCACAGACACCGTACATTTTCTCAGGAAGTATTTGGGATAATCTTAAGTTAGGTAATCGGCCAGGAATCAC
ACAAGCGGACATCATGCATGCGTGTGAGCTAGCAGAGATAAAGAATGATATTGAAAAAATGCCGCTCCAATTTGAAACAT
TATTGGATGAAGATGGAAACACATTGTCAGGTGGTCAAAAACAGCGATTAACAATTGCGCGAGCACTATTATCACCAGCT
CGGGTACTAATTTTTGATGAGTCTACTAGTGGGTTAGATACGATAACAGAGGGGCTATTAGTTGATCATCTAATGGCGTT
AGAAGAAAGAACAATCATTTTCATAGCGCATCGTTTAGCGATTGCTAAGAAAACGAACAATATTCTTGTTTTAGAAAATG
GTAGTGTTGTTGAAACTGGGACACATGATGCGTTGGTGGATACACAAGGGCGATATTACCAATTGCTCAATCATTAG
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| comA | Streptococcus mitis NCTC 12261 |
58.824 |
99.443 |
0.585 |
| comA | Streptococcus pneumoniae TIGR4 |
58.263 |
99.443 |
0.579 |
| comA | Streptococcus mitis SK321 |
58.263 |
99.443 |
0.579 |
| comA | Streptococcus pneumoniae R6 |
58.123 |
99.443 |
0.578 |
| comA | Streptococcus pneumoniae Rx1 |
58.123 |
99.443 |
0.578 |
| comA | Streptococcus pneumoniae D39 |
58.123 |
99.443 |
0.578 |
| comA | Streptococcus gordonii str. Challis substr. CH1 |
56.723 |
99.443 |
0.564 |
| comA/nlmT | Streptococcus mutans UA159 |
54.366 |
98.886 |
0.538 |