Detailed information NTG0302392

Bioinformatically predicted

Overview

• Name: htrA
• Type: Regulator
• Locus tag: DR994_RS09635
• Genome accession: NZ_CP030927
• Coordinates: 1858681..1859916 (+)
• Length: 411 a.a.
• NCBI ID: WP_011226713.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus strain CS9
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1853681..1864916

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DR994_RS09605 (DR994_09835)	-	1854148..1856754 (+)	2607	WP_173940695.1	YfhO family protein	-
DR994_RS09625 (DR994_09855)	-	1857298..1857981 (-)	684	WP_096811735.1	YoaK family protein	-
DR994_RS09630 (DR994_09860)	rlmH	1857997..1858476 (-)	480	WP_002952297.1	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH	-
DR994_RS09635 (DR994_09865)	htrA	1858681..1859916 (+)	1236	WP_011226713.1	trypsin-like peptidase domain-containing protein	Regulator
DR994_RS09640 (DR994_09870)	spo0J	1859982..1860749 (+)	768	WP_002952299.1	ParB/RepB/Spo0J family partition protein	Regulator

Sequence

Protein

• Length: 411 a.a.
• Molecular weight: 42859.14 Da
• Isoelectric Point: 4.7061

>NTDB_id=302392 DR994_RS09635 WP_011226713.1 1858681..1859916(+) (htrA) [Streptococcus thermophilus strain CS9]
MKKFNWKKIVAPIAMLIIGLLGGLLGAFILLTAAGVSFTNTTDTGVKTAKTVYTNITDTTKAVKKVQNAVVSVINYQEGS
SSDSLNDLYGRIFGGGDSSDSSQENSKDSDGLQVAGEGSGVIYKKDGKEAYIVTNNHVVDGAKKLEIMLSDGSKITGELV
GKDTYSDLAVVKVSSDKITTVAEFADSNSLTVGEKAIAIGSPLGTEYANSVTEGIVSSLSRTITMQNDNGETVSTNAIQT
DAAINPGNSGGALVNIEGQVIGINSSKISSTSAVAGSAVEGMGFAIPSNDVVEIINQLEKDGKVTRPALGISIADLNSLS
SSATSKLDLPDEVKSGVVVGSVQKGMPADGKLQEYDVITEIDGKKISSKTDIQTNLYSHSIGDTIKVTFYRGKDKKTVDL
KLTKSTEDISD

Nucleotide

• Length: 1236 bp

>NTDB_id=302392 DR994_RS09635 WP_011226713.1 1858681..1859916(+) (htrA) [Streptococcus thermophilus strain CS9]
ATGAAAAAATTTAACTGGAAGAAGATAGTCGCGCCAATTGCAATGCTAATTATTGGCTTACTAGGTGGTTTACTTGGTGC
CTTTATCCTACTAACAGCAGCCGGGGTATCTTTTACCAATACAACAGATACTGGAGTAAAAACGGCTAAGACCGTCTACA
CCAATATAACAGATACAACTAAGGCTGTTAAGAAAGTACAAAATGCTGTTGTTTCTGTCATCAATTATCAAGAAGGTTCA
TCTTCAGATTCTCTAAATGACCTTTATGGCCGTATCTTTGGCGGAGGGGACAGTTCTGATTCTAGCCAAGAAAATTCAAA
AGATTCAGATGGTCTGCAGGTCGCTGGTGAAGGTTCTGGAGTCATCTATAAAAAAGATGGCAAAGAAGCCTACATCGTAA
CCAATAACCACGTTGTCGATGGGGCTAAAAAACTTGAAATCATGCTTTCGGATGGTTCGAAAATTACTGGTGAACTTGTT
GGTAAAGACACTTACTCTGACCTAGCAGTTGTCAAAGTATCTTCAGATAAAATAACAACTGTTGCAGAATTTGCAGACTC
AAACTCCCTTACTGTTGGTGAAAAAGCAATTGCTATCGGTAGCCCACTTGGTACCGAATACGCCAACTCAGTAACAGAAG
GAATCGTTTCTAGCCTTAGCCGTACTATAACGATGCAAAACGATAATGGTGAAACTGTATCAACAAACGCTATCCAAACA
GATGCAGCCATTAACCCTGGTAACTCTGGTGGTGCCCTAGTCAATATTGAAGGACAAGTTATCGGTATTAATTCAAGTAA
AATTTCATCAACGTCTGCAGTCGCTGGTAGTGCTGTTGAAGGTATGGGGTTTGCCATTCCATCAAACGATGTTGTTGAAA
TCATCAATCAATTAGAAAAAGATGGTAAAGTTACACGACCAGCACTAGGAATCTCAATAGCAGATCTTAATAGCCTTTCT
AGCAGCGCAACTTCTAAATTAGATTTACCAGATGAGGTCAAATCCGGTGTTGTTGTCGGTAGTGTTCAGAAAGGTATGCC
AGCTGACGGTAAACTTCAAGAATATGATGTTATCACTGAGATTGATGGTAAGAAAATCAGCTCAAAAACTGATATTCAAA
CCAATCTTTACAGCCATAGTATTGGAGATACTATCAAGGTAACCTTCTATCGTGGTAAAGATAAGAAAACTGTAGATCTT
AAATTAACAAAATCTACAGAAGACATATCTGATTAA

Domains

Predicted by InterproScan.

• Peptidase family M50 (Peptidase_M50) (4-406)

• PDZ domain (PDZ_2) (307-402)

• Trypsin-like peptidase domain (Trypsin_2) (118-263)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
htrA	Streptococcus mutans UA159	61.787	98.054	0.606
htrA	Streptococcus gordonii str. Challis substr. CH1	57.282	100	0.574
htrA	Streptococcus mitis NCTC 12261	53.79	99.513	0.535
htrA	Streptococcus pneumoniae TIGR4	53.545	99.513	0.533
htrA	Streptococcus pneumoniae D39	53.545	99.513	0.533
htrA	Streptococcus pneumoniae Rx1	53.545	99.513	0.533
htrA	Streptococcus pneumoniae R6	53.545	99.513	0.533