Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   DR994_RS06605 Genome accession   NZ_CP030927
Coordinates   1281562..1282311 (-) Length   249 a.a.
NCBI ID   WP_173940587.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain CS9     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1276562..1287311
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DR994_RS06585 (DR994_06770) - 1276885..1278117 (-) 1233 WP_173940585.1 cysteine desulfurase -
  DR994_RS06590 (DR994_06775) sufD 1278171..1279433 (-) 1263 WP_173940586.1 Fe-S cluster assembly protein SufD -
  DR994_RS06595 (DR994_06780) sufC 1279470..1280240 (-) 771 WP_002947634.1 Fe-S cluster assembly ATPase SufC -
  DR994_RS06600 (DR994_06785) - 1280401..1281558 (-) 1158 WP_002947632.1 MraY family glycosyltransferase -
  DR994_RS06605 (DR994_06790) mecA 1281562..1282311 (-) 750 WP_173940587.1 adaptor protein MecA Regulator
  DR994_RS06610 (DR994_06795) - 1282595..1282792 (+) 198 WP_224103664.1 DUF3021 family protein -
  DR994_RS06615 (DR994_06800) - 1282938..1283792 (-) 855 WP_041828107.1 undecaprenyl-diphosphate phosphatase -
  DR994_RS06620 (DR994_06805) - 1283995..1285545 (+) 1551 WP_011225362.1 ABC transporter substrate-binding protein/permease -
  DR994_RS06625 (DR994_06810) - 1285545..1286285 (+) 741 WP_002949253.1 amino acid ABC transporter ATP-binding protein -
  DR994_RS06630 (DR994_06815) - 1286373..1286480 (-) 108 WP_084829946.1 LPXTG cell wall anchor domain-containing protein -
  DR994_RS06635 - 1286567..1286737 (-) 171 WP_172838670.1 hypothetical protein -

Sequence

Protein


Download         Length: 249 a.a.        Molecular weight: 29156.71 Da        Isoelectric Point: 4.0844

>NTDB_id=302369 DR994_RS06605 WP_173940587.1 1281562..1282311(-) (mecA) [Streptococcus thermophilus strain CS9]
MEMKQINETTLKIMITMEDLEEHGMELKDFLIPQEKTEEFFYTVMDELDLPDNFKNSGMLSFRVTPRKDRVDVFVTKSDL
KEALDFNDLSDMEDYSGLSPEEFLKALEDNFMDKGDIEAHHKLEEHDKTLKEVDETMTEPAKEVAEETIREDYTHYVLAF
SDFDQVVTFAQGLKNVSVEGSEFYKLGDVYYMTILLYLADEPNYYANNMYARFLEYANVADRTRPYLQEHATILMEEDAL
PVLQATKWS

Nucleotide


Download         Length: 750 bp        

>NTDB_id=302369 DR994_RS06605 WP_173940587.1 1281562..1282311(-) (mecA) [Streptococcus thermophilus strain CS9]
ATGGAAATGAAACAAATAAACGAGACAACTCTAAAAATCATGATTACCATGGAAGATCTTGAAGAACATGGTATGGAGCT
GAAAGATTTCTTGATTCCCCAGGAAAAAACAGAGGAATTTTTCTATACTGTCATGGATGAGTTGGACTTGCCTGATAACT
TTAAAAATAGTGGGATGTTGAGCTTCCGTGTCACGCCACGAAAGGATCGTGTGGATGTTTTTGTGACTAAATCAGATCTT
AAGGAAGCCCTTGATTTCAATGATTTGTCAGATATGGAAGACTATTCAGGACTTTCTCCAGAAGAATTCCTCAAAGCTCT
TGAAGATAACTTTATGGATAAGGGAGATATTGAAGCCCACCATAAGCTCGAAGAGCATGATAAGACCTTGAAAGAGGTTG
ATGAGACTATGACAGAGCCGGCTAAGGAAGTGGCTGAGGAAACTATTCGTGAAGATTATACTCACTATGTCTTGGCTTTC
TCTGACTTTGATCAAGTAGTGACCTTTGCGCAAGGTTTGAAGAATGTGTCAGTGGAGGGTTCTGAATTTTATAAACTTGG
TGATGTCTACTATATGACTATCCTTCTTTACTTGGCTGATGAGCCTAATTATTACGCGAACAATATGTATGCGCGTTTTC
TTGAATATGCGAATGTGGCAGACCGAACACGTCCCTATCTACAAGAGCATGCAACAATCTTGATGGAAGAGGACGCCTTA
CCGGTATTACAAGCAACGAAATGGAGCTAG

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-242)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus thermophilus LMG 18311

99.598

100

0.996
  mecA Streptococcus thermophilus LMD-9

98.795

100

0.988
  mecA Streptococcus mutans UA159

56.967

97.992

0.558
  mecA Streptococcus pneumoniae Rx1

46.185

100

0.462
  mecA Streptococcus pneumoniae D39

46.185

100

0.462
  mecA Streptococcus pneumoniae R6

46.185

100

0.462
  mecA Streptococcus pneumoniae TIGR4

46.185

100

0.462

Multiple sequence alignment