Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   ETT69_RS01635 Genome accession   NZ_CP035430
Coordinates   288709..289470 (+) Length   253 a.a.
NCBI ID   WP_011106593.1    Uniprot ID   P0DC31
Organism   Streptococcus pyogenes strain emm55     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 283709..294470
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ETT69_RS01620 (ETT69_01620) - 283985..285553 (-) 1569 WP_002991130.1 ABC transporter substrate-binding protein/permease -
  ETT69_RS01625 (ETT69_01625) - 285751..287658 (+) 1908 Protein_271 DUF2207 domain-containing protein -
  ETT69_RS01630 (ETT69_01630) - 287724..288563 (+) 840 WP_011184167.1 undecaprenyl-diphosphate phosphatase -
  ETT69_RS01635 (ETT69_01635) mecA 288709..289470 (+) 762 WP_011106593.1 adaptor protein MecA Regulator
  ETT69_RS01640 (ETT69_01640) - 289477..290646 (+) 1170 WP_011184169.1 glycosyltransferase family 4 protein -
  ETT69_RS01645 (ETT69_01645) sufC 290768..291538 (+) 771 WP_002986023.1 Fe-S cluster assembly ATPase SufC -
  ETT69_RS01650 (ETT69_01650) sufD 291633..292895 (+) 1263 WP_136019604.1 Fe-S cluster assembly protein SufD -
  ETT69_RS01655 (ETT69_01655) - 292926..294152 (+) 1227 WP_032460421.1 cysteine desulfurase -

Sequence

Protein


Download         Length: 253 a.a.        Molecular weight: 29051.68 Da        Isoelectric Point: 4.1282

>NTDB_id=301162 ETT69_RS01635 WP_011106593.1 288709..289470(+) (mecA) [Streptococcus pyogenes strain emm55]
MEMKQISETTLKITISMDDLEERGMELKDFLIPQEKTEEFFYSVMDELDLPDNFKDSGMLSFRVTPRKDRLDVFVTKSEI
NKDINLEDLAEFGDMSQMTPEDFFKSLEQSMREKGDVKAHEKLEQIEEIMEDVVEATLANQSEAADPSTNHESEPLDYVH
YVLDFSTITEAVAFAKTIDFSIEASELYKGSNCYHMTILLDVQQQPSYFANVMYARLIEHANPGSKTRAYLQEHGLQLML
DGAVEQLQKIELG

Nucleotide


Download         Length: 762 bp        

>NTDB_id=301162 ETT69_RS01635 WP_011106593.1 288709..289470(+) (mecA) [Streptococcus pyogenes strain emm55]
ATGGAAATGAAACAAATTAGCGAGACAACGCTAAAAATAACAATTAGTATGGACGATTTAGAAGAAAGAGGAATGGAGTT
GAAAGATTTCTTGATTCCTCAAGAAAAAACAGAAGAGTTTTTCTATTCTGTGATGGACGAACTCGATCTTCCAGATAATT
TTAAAGATAGTGGTATGCTTAGTTTTCGAGTGACTCCACGCAAGGACCGTCTAGATGTTTTTGTTACCAAATCTGAGATA
AATAAAGATATTAATCTTGAAGATTTAGCAGAGTTTGGTGATATGTCCCAAATGACTCCGGAAGATTTTTTCAAGAGCTT
GGAGCAATCCATGCGTGAAAAGGGAGATGTCAAAGCTCATGAAAAATTGGAACAAATTGAAGAGATAATGGAAGATGTTG
TTGAAGCCACTCTAGCTAATCAGTCTGAGGCGGCTGATCCATCAACTAATCATGAGTCAGAACCTTTAGACTATGTCCAT
TATGTATTGGATTTTTCAACGATTACAGAGGCAGTGGCTTTTGCTAAAACGATTGATTTTTCGATAGAAGCTTCAGAGTT
ATATAAGGGGAGCAACTGCTACCATATGACTATTTTATTAGATGTTCAGCAACAACCATCTTATTTTGCGAATGTCATGT
ATGCGAGATTGATTGAGCATGCAAACCCTGGATCAAAAACAAGAGCTTATTTACAAGAGCATGGCTTACAATTGATGCTT
GATGGTGCTGTTGAGCAATTACAAAAGATTGAGTTGGGATAA

Domains

Predicted by InterProScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-247)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P0DC31

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus mutans UA159

63.2

98.814

0.625
  mecA Streptococcus thermophilus LMD-9

56.225

98.419

0.553
  mecA Streptococcus thermophilus LMG 18311

55.422

98.419

0.545
  mecA Streptococcus pneumoniae Rx1

48.627

100

0.49
  mecA Streptococcus pneumoniae D39

48.627

100

0.49
  mecA Streptococcus pneumoniae R6

48.627

100

0.49
  mecA Streptococcus pneumoniae TIGR4

48.627

100

0.49