Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   DQ228_RS01530 Genome accession   NZ_CP030250
Coordinates   283067..283756 (+) Length   229 a.a.
NCBI ID   WP_014607969.1    Uniprot ID   A0A2H4K9N5
Organism   Streptococcus thermophilus strain CS20     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 278067..288756
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQ228_RS01505 - 279033..279203 (+) 171 Protein_271 ascorbate 6-phosphate lactonase -
  DQ228_RS01510 - 279220..279891 (-) 672 WP_002946492.1 potassium channel family protein -
  DQ228_RS01515 - 279931..281295 (-) 1365 WP_014607967.1 TrkH family potassium uptake protein -
  DQ228_RS01520 rsmG 281365..282078 (-) 714 WP_002946490.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -
  DQ228_RS01525 - 282375..282911 (+) 537 WP_002946488.1 DUF177 domain-containing protein -
  DQ228_RS01530 covR 283067..283756 (+) 690 WP_014607969.1 response regulator transcription factor Regulator
  DQ228_RS01535 covS 283753..285270 (+) 1518 WP_232979750.1 HAMP domain-containing histidine kinase Regulator
  DQ228_RS01540 nrdR 285392..285871 (+) 480 WP_002949642.1 transcriptional regulator NrdR -
  DQ228_RS01545 - 285868..287043 (+) 1176 WP_232979749.1 DnaD domain protein -
  DQ228_RS01550 dnaI 287047..287949 (+) 903 WP_011680740.1 primosomal protein DnaI -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26637.73 Da        Isoelectric Point: 4.7059

>NTDB_id=300410 DQ228_RS01530 WP_014607969.1 283067..283756(+) (covR) [Streptococcus thermophilus strain CS20]
MSKRILIVEDERNLARFVSLELQHEGYDVVTADNGREGLELALEKDFDLILLDLMLPEMDGFEVTRRLQQEKDTYIMMMT
ARDSIMDIVAGLDRGADDYIIKPFAIEELLARIRATFRRQDIEATKKAPAKASTYRDLKLDVQNRAVVRGDEVIPLTKRE
FDLLNTLLSNMNQVMTREELLLQVWKYDDVIETNVVDVYIRYLRGKIDIPGKESYIQTVRGMGYVIRER

Nucleotide


Download         Length: 690 bp        

>NTDB_id=300410 DQ228_RS01530 WP_014607969.1 283067..283756(+) (covR) [Streptococcus thermophilus strain CS20]
ATGAGCAAACGCATTTTGATTGTTGAAGATGAGAGAAACCTTGCTCGTTTTGTCTCTCTTGAACTTCAACACGAAGGATA
CGACGTTGTGACAGCGGACAACGGACGCGAAGGACTTGAATTGGCACTTGAGAAAGATTTCGATCTTATTCTCTTGGACC
TTATGTTGCCTGAGATGGACGGTTTCGAAGTGACACGTCGTCTCCAACAAGAAAAAGATACTTATATTATGATGATGACA
GCTCGCGACTCAATCATGGATATTGTTGCTGGTTTGGATCGTGGAGCTGATGACTATATTATAAAACCATTTGCGATTGA
AGAACTGTTGGCACGTATTCGTGCAACCTTCCGTCGTCAAGATATCGAAGCTACTAAGAAGGCACCAGCTAAAGCGTCAA
CCTATCGCGATTTAAAATTGGATGTTCAAAACCGTGCAGTTGTTCGCGGTGATGAGGTAATTCCATTGACAAAACGTGAG
TTTGATTTGTTGAACACACTTTTAAGCAATATGAACCAAGTAATGACCCGTGAGGAACTCTTGCTTCAAGTCTGGAAATA
TGATGACGTAATTGAAACAAACGTTGTAGATGTTTATATTCGTTACTTACGTGGGAAAATCGACATTCCAGGTAAGGAAT
CATACATTCAGACAGTACGAGGGATGGGTTACGTTATCCGTGAAAGATGA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-114)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(152-225)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2H4K9N5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

95.633

100

0.956
  covR Lactococcus lactis subsp. lactis strain DGCC12653

67.544

99.563

0.672
  vicR Streptococcus mutans UA159

45.259

100

0.459
  micA Streptococcus pneumoniae Cp1015

43.913

100

0.441

Multiple sequence alignment