Detailed information    

insolico Bioinformatically predicted

Overview

Name   covS   Type   Regulator
Locus tag   DQ228_RS01535 Genome accession   NZ_CP030250
Coordinates   283753..285270 (+) Length   505 a.a.
NCBI ID   WP_232979750.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain CS20     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 278753..290270
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQ228_RS01505 - 279033..279203 (+) 171 Protein_271 ascorbate 6-phosphate lactonase -
  DQ228_RS01510 - 279220..279891 (-) 672 WP_002946492.1 potassium channel family protein -
  DQ228_RS01515 - 279931..281295 (-) 1365 WP_014607967.1 TrkH family potassium uptake protein -
  DQ228_RS01520 rsmG 281365..282078 (-) 714 WP_002946490.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -
  DQ228_RS01525 - 282375..282911 (+) 537 WP_002946488.1 DUF177 domain-containing protein -
  DQ228_RS01530 covR 283067..283756 (+) 690 WP_014607969.1 response regulator transcription factor Regulator
  DQ228_RS01535 covS 283753..285270 (+) 1518 WP_232979750.1 HAMP domain-containing histidine kinase Regulator
  DQ228_RS01540 nrdR 285392..285871 (+) 480 WP_002949642.1 transcriptional regulator NrdR -
  DQ228_RS01545 - 285868..287043 (+) 1176 WP_232979749.1 DnaD domain protein -
  DQ228_RS01550 dnaI 287047..287949 (+) 903 WP_011680740.1 primosomal protein DnaI -
  DQ228_RS01555 der 288055..289365 (+) 1311 WP_011680741.1 ribosome biogenesis GTPase Der -
  DQ228_RS10085 - 289429..290088 (+) 660 Protein_282 HI_0552 family protein -

Sequence

Protein


Download         Length: 505 a.a.        Molecular weight: 57623.02 Da        Isoelectric Point: 5.1757

>NTDB_id=300411 DQ228_RS01535 WP_232979750.1 283753..285270(+) (covS) [Streptococcus thermophilus strain CS20]
MSKLFGKVTIRKKLTMTTAVVFFLVLSMFTLVVVFSANTLLLQRERQNVNNTISKVVTYIEKDWDSDEELSPEPLLAALY
SPKNIYPSIINGVLSEKRSLDGQVAVSNRLYSNQSIYVYDKKGTFIFTSEEDTDSPPGMSEVNKLKLVSYKGKRGFLLQV
PIYGKDKKTIVGYAQVFHDLEFYYALKERLIFLLIFLEVGMTVLVIAVTVVVLTSILRPMRQLHETMGIIIDSPSDLELR
SKIESHDEIGALALNFNCMMDKIQENNQMQMRFLSDVSHELRTPIAVIKGHMDLLQRWGKNDPEILEESLEAASHEANRM
TIMINDMLDSIRVKESFDNHRNDTCDLNSSIRTVIGNFRVLHDDYQFYLNDSEGSDRPAQIYSQHFEQVITILIDNAVKY
SPVNKKIQITIKALEDEMLVQVQDNGEGISKEDIEHIFERFYRSDKARNRTTTQSGVGIGLSILYQIVEAYRCHIDVSSE
LGVGTRFDLYIPFAESETTTPQIEG

Nucleotide


Download         Length: 1518 bp        

>NTDB_id=300411 DQ228_RS01535 WP_232979750.1 283753..285270(+) (covS) [Streptococcus thermophilus strain CS20]
ATGAGTAAATTATTTGGTAAAGTAACCATTAGAAAAAAGTTGACCATGACAACTGCTGTGGTCTTCTTTCTTGTATTGTC
GATGTTCACTCTGGTTGTTGTATTTTCAGCCAATACGCTTCTTTTGCAACGTGAACGTCAAAATGTAAATAATACAATCT
CAAAAGTTGTTACTTATATCGAAAAGGACTGGGACTCTGATGAAGAGTTGAGTCCAGAGCCGCTTTTAGCGGCCCTTTAT
TCACCGAAAAATATCTATCCATCAATCATTAATGGAGTGCTTTCTGAAAAGCGTTCCTTAGATGGTCAAGTTGCGGTTTC
TAATAGATTATATTCCAACCAGTCTATCTATGTTTATGACAAAAAGGGAACTTTTATCTTTACTTCTGAGGAGGATACAG
ACTCACCTCCAGGCATGTCTGAGGTCAATAAACTGAAGTTGGTTTCCTATAAAGGTAAACGTGGTTTCTTACTACAAGTT
CCAATCTATGGCAAGGATAAGAAGACCATTGTTGGGTATGCTCAAGTTTTCCATGATTTGGAATTCTACTATGCGTTAAA
AGAGCGTTTAATTTTCCTATTGATATTCCTTGAAGTAGGAATGACGGTCTTAGTTATTGCAGTAACTGTAGTTGTCTTGA
CATCTATTCTTCGTCCGATGAGGCAGTTACACGAAACGATGGGTATTATTATCGATTCGCCAAGTGATTTGGAGCTTCGA
TCTAAGATTGAGAGTCATGATGAGATTGGTGCTTTGGCACTTAACTTTAACTGTATGATGGATAAAATTCAAGAAAATAA
TCAGATGCAGATGCGTTTCTTGAGTGACGTCAGTCACGAATTACGTACTCCCATTGCAGTTATTAAAGGACATATGGACC
TCTTGCAACGTTGGGGTAAAAATGATCCTGAAATCCTTGAAGAAAGTCTTGAAGCTGCAAGTCATGAAGCCAACCGTATG
ACGATTATGATTAACGATATGTTGGATTCTATTCGTGTTAAAGAGTCATTTGACAATCATAGAAATGATACATGTGATTT
GAATTCTTCAATCCGTACGGTTATTGGGAATTTTCGTGTCCTACATGACGACTACCAATTCTACCTCAATGATTCTGAGG
GTTCAGATCGTCCAGCACAGATTTACAGCCAGCACTTTGAACAGGTTATTACTATTTTGATTGATAATGCGGTCAAGTAT
TCGCCTGTTAATAAGAAAATCCAGATTACTATCAAGGCTCTGGAAGATGAGATGCTGGTACAGGTACAGGATAATGGTGA
GGGTATCTCTAAAGAAGATATTGAACATATATTTGAACGCTTCTATCGTTCAGATAAGGCGCGTAATCGTACGACAACCC
AATCTGGTGTGGGTATTGGTTTATCAATCCTCTATCAAATTGTGGAAGCTTATCGATGCCATATCGATGTCAGTTCAGAA
CTTGGTGTGGGTACACGTTTTGACCTCTACATTCCTTTTGCAGAGTCAGAAACTACGACACCTCAAATTGAAGGTTAA

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(270-329)

ArlS sensor domain (ArlS_N)

(39-187)

HAMP domain (HAMP)

(213-265)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(384-494)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covS Streptococcus salivarius strain HSISS4

94.223

99.406

0.937

Multiple sequence alignment