Detailed information
Bioinformatically predicted
Overview
| Name | clpP | Type | Regulator |
| Locus tag | SPH_RS04090 | Genome accession | NC_010380 |
| Coordinates | 785650..786240 (+) | Length | 196 a.a. |
| NCBI ID | WP_000613477.1 | Uniprot ID | A0A064BX72 |
| Organism | Streptococcus pneumoniae Hungary19A-6 | ||
| Function | degradation of ComX; degradation of ComW (predicted from homology) Competence regulation |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| Prophage | 784291..795195 | 785650..786240 | within | 0 |
Gene organization within MGE regions
Location: 784291..795195
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| SPH_RS04080 (SPH_0846) | - | 784291..784758 (+) | 468 | WP_000136976.1 | cytidine/deoxycytidylate deaminase family protein | - |
| SPH_RS04085 (SPH_0847) | upp | 784847..785476 (+) | 630 | WP_000515974.1 | uracil phosphoribosyltransferase | - |
| SPH_RS04090 (SPH_0848) | clpP | 785650..786240 (+) | 591 | WP_000613477.1 | ATP-dependent Clp protease proteolytic subunit ClpP | Regulator |
| SPH_RS04095 (SPH_0849) | - | 786319..786567 (+) | 249 | WP_000462126.1 | YlbG family protein | - |
| SPH_RS04100 (SPH_0850) | - | 786669..787829 (+) | 1161 | WP_000726153.1 | ABC transporter substrate-binding protein | - |
| SPH_RS04105 (SPH_0851) | - | 788097..788966 (+) | 870 | WP_000941421.1 | branched-chain amino acid ABC transporter permease | - |
| SPH_RS04110 (SPH_0852) | - | 788970..789926 (+) | 957 | WP_000662293.1 | branched-chain amino acid ABC transporter permease | - |
| SPH_RS04115 (SPH_0853) | - | 789926..790690 (+) | 765 | WP_001186007.1 | ABC transporter ATP-binding protein | - |
| SPH_RS04120 (SPH_0854) | - | 790690..791400 (+) | 711 | WP_000062219.1 | ABC transporter ATP-binding protein | - |
| SPH_RS04125 (SPH_0855) | - | 791707..792363 (+) | 657 | WP_000268677.1 | CBS domain-containing protein | - |
| SPH_RS04130 (SPH_0856) | prfB | 792471..793566 (+) | 1096 | WP_015511312.1 | peptide chain release factor 2 | - |
| SPH_RS04135 (SPH_0857) | ftsE | 793584..794276 (+) | 693 | WP_000022265.1 | cell division ATP-binding protein FtsE | - |
| SPH_RS04140 (SPH_0858) | ftsX | 794269..795195 (+) | 927 | WP_000625537.1 | permease-like cell division protein FtsX | - |
Sequence
Protein
Download Length: 196 a.a. Molecular weight: 21358.36 Da Isoelectric Point: 4.4910
>NTDB_id=30002 SPH_RS04090 WP_000613477.1 785650..786240(+) (clpP) [Streptococcus pneumoniae Hungary19A-6]
MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSVIAQLLFLDAQDSTKDIYLYVNTPGGSVSAGLAIVDTMN
FIKADVQTIVMGMAASMGTVIASSGAKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRNTLEKILAENSGQ
SMEKVHADAERDNWMSAQETLEYGFIDEIMANNSLN
MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSVIAQLLFLDAQDSTKDIYLYVNTPGGSVSAGLAIVDTMN
FIKADVQTIVMGMAASMGTVIASSGAKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRNTLEKILAENSGQ
SMEKVHADAERDNWMSAQETLEYGFIDEIMANNSLN
Nucleotide
Download Length: 591 bp
>NTDB_id=30002 SPH_RS04090 WP_000613477.1 785650..786240(+) (clpP) [Streptococcus pneumoniae Hungary19A-6]
ATGATTCCTGTAGTTATTGAACAAACAAGCCGTGGAGAACGTTCTTACGATATTTACTCACGTCTTCTCAAAGACCGCAT
CATTATGCTGACAGGTCCGGTTGAAGACAATATGGCTAACTCTGTTATTGCCCAATTGCTTTTCTTGGATGCCCAAGATA
GTACAAAAGATATTTACCTTTATGTCAATACACCAGGTGGTTCTGTTTCAGCTGGTTTGGCAATCGTAGATACCATGAAC
TTTATCAAGGCAGATGTCCAAACCATTGTTATGGGAATGGCTGCATCTATGGGGACTGTCATCGCATCAAGTGGGGCAAA
AGGCAAACGTTTCATGCTTCCAAATGCTGAATACATGATTCACCAACCAATGGGCGGTACAGGTGGTGGTACCCAACAAA
CTGATATGGCTATCGCTGCAGAACACTTGCTCAAAACTCGTAATACCTTGGAAAAAATCTTGGCTGAAAATTCAGGTCAG
TCAATGGAAAAAGTCCATGCAGATGCAGAACGTGATAACTGGATGAGCGCCCAGGAAACACTTGAATATGGCTTTATTGA
TGAAATTATGGCCAACAATTCATTGAACTAA
ATGATTCCTGTAGTTATTGAACAAACAAGCCGTGGAGAACGTTCTTACGATATTTACTCACGTCTTCTCAAAGACCGCAT
CATTATGCTGACAGGTCCGGTTGAAGACAATATGGCTAACTCTGTTATTGCCCAATTGCTTTTCTTGGATGCCCAAGATA
GTACAAAAGATATTTACCTTTATGTCAATACACCAGGTGGTTCTGTTTCAGCTGGTTTGGCAATCGTAGATACCATGAAC
TTTATCAAGGCAGATGTCCAAACCATTGTTATGGGAATGGCTGCATCTATGGGGACTGTCATCGCATCAAGTGGGGCAAA
AGGCAAACGTTTCATGCTTCCAAATGCTGAATACATGATTCACCAACCAATGGGCGGTACAGGTGGTGGTACCCAACAAA
CTGATATGGCTATCGCTGCAGAACACTTGCTCAAAACTCGTAATACCTTGGAAAAAATCTTGGCTGAAAATTCAGGTCAG
TCAATGGAAAAAGTCCATGCAGATGCAGAACGTGATAACTGGATGAGCGCCCAGGAAACACTTGAATATGGCTTTATTGA
TGAAATTATGGCCAACAATTCATTGAACTAA
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| clpP | Streptococcus pneumoniae Rx1 |
100 |
100 |
1 |
| clpP | Streptococcus pneumoniae D39 |
100 |
100 |
1 |
| clpP | Streptococcus pneumoniae R6 |
100 |
100 |
1 |
| clpP | Streptococcus pneumoniae TIGR4 |
100 |
100 |
1 |
| clpP | Streptococcus thermophilus LMG 18311 |
92.821 |
99.49 |
0.923 |
| clpP | Streptococcus thermophilus LMD-9 |
92.821 |
99.49 |
0.923 |
| clpP | Streptococcus pyogenes JRS4 |
90.769 |
99.49 |
0.903 |
| clpP | Streptococcus pyogenes MGAS315 |
90.769 |
99.49 |
0.903 |
| clpP | Streptococcus mutans UA159 |
85.714 |
100 |
0.857 |
| clpP | Lactococcus lactis subsp. lactis strain DGCC12653 |
85.128 |
99.49 |
0.847 |
| clpP | Lactococcus lactis subsp. cremoris KW2 |
84.615 |
99.49 |
0.842 |
| clpP | Bacillus subtilis subsp. subtilis str. 168 |
58.854 |
97.959 |
0.577 |
| clpP | Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819 |
58.031 |
98.469 |
0.571 |