Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   DP112_RS09080 Genome accession   NZ_CP030125
Coordinates   1821843..1822565 (-) Length   240 a.a.
NCBI ID   WP_114866815.1    Uniprot ID   -
Organism   Streptococcus suis strain HA1003     
Function   degradation of ComW (predicted from homology)   
Competence regulation

Genomic Context

Location: 1816843..1827565
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DP112_RS09060 (DP112_09060) - 1816999..1818222 (-) 1224 WP_114866813.1 cysteine desulfurase -
  DP112_RS09065 (DP112_09065) sufD 1818226..1819488 (-) 1263 WP_114867035.1 Fe-S cluster assembly protein SufD -
  DP112_RS09070 (DP112_09070) sufC 1819505..1820278 (-) 774 WP_002938165.1 Fe-S cluster assembly ATPase SufC -
  DP112_RS09075 (DP112_09075) - 1820674..1821846 (-) 1173 WP_114866814.1 MraY family glycosyltransferase -
  DP112_RS09080 (DP112_09080) mecA 1821843..1822565 (-) 723 WP_114866815.1 adaptor protein MecA Regulator
  DP112_RS09085 (DP112_09085) - 1822693..1823529 (-) 837 WP_014638628.1 undecaprenyl-diphosphate phosphatase -
  DP112_RS09090 (DP112_09090) - 1823656..1825221 (+) 1566 WP_105140450.1 ABC transporter substrate-binding protein/permease -
  DP112_RS09095 (DP112_09095) - 1825214..1825957 (+) 744 WP_012775335.1 amino acid ABC transporter ATP-binding protein -
  DP112_RS09100 (DP112_09100) - 1826080..1826289 (-) 210 WP_009910800.1 hypothetical protein -
  DP112_RS09105 (DP112_09105) - 1826372..1827277 (-) 906 WP_024389694.1 SPFH domain-containing protein -

Sequence

Protein


Download         Length: 240 a.a.        Molecular weight: 27987.54 Da        Isoelectric Point: 4.0533

>NTDB_id=299502 DP112_RS09080 WP_114866815.1 1821843..1822565(-) (mecA) [Streptococcus suis strain HA1003]
MKVKQISDSTLKITIKLEDLEERGMELSDFLIPQEKTEEFFYTVLDELDLPMTFRESGMLSFRVTPKPDRVDIFVTKSDL
DQSLNFDEFTDLSELGDVASMTPDEFFKSLEQTVREKSAPDATAVRHLEEVEQEEEADEEEQERYIYYILEFPTIEDLFT
FVGTVDYPVEESELYKMDGHYYLTVLINVENRSKQYPGYILSRMLEFTNDTKLTRPALQEHGTLMLPLAAIEELRKVPTV

Nucleotide


Download         Length: 723 bp        

>NTDB_id=299502 DP112_RS09080 WP_114866815.1 1821843..1822565(-) (mecA) [Streptococcus suis strain HA1003]
ATGAAAGTAAAGCAAATTAGTGATTCAACCTTGAAAATCACTATAAAATTAGAGGATTTGGAAGAGAGAGGAATGGAACT
TTCGGACTTTCTCATTCCGCAAGAAAAGACAGAGGAGTTCTTCTATACTGTTTTGGATGAATTGGATTTACCAATGACTT
TCCGAGAAAGCGGTATGCTGAGTTTTCGTGTGACTCCGAAGCCAGATCGGGTGGACATCTTTGTTACCAAGTCTGATTTG
GATCAGAGCTTGAATTTCGATGAATTTACAGATTTGTCGGAACTTGGTGATGTCGCAAGTATGACTCCAGATGAGTTTTT
CAAGAGTTTGGAGCAAACCGTTCGTGAGAAAAGTGCACCGGATGCAACAGCCGTTCGTCATTTGGAAGAGGTAGAGCAAG
AGGAAGAAGCAGATGAAGAGGAGCAGGAGCGCTATATTTACTATATCTTGGAATTTCCAACGATAGAGGATCTGTTTACT
TTTGTTGGTACGGTTGATTATCCAGTAGAAGAATCAGAATTATATAAAATGGATGGTCACTACTACTTGACCGTTCTTAT
CAATGTAGAAAATCGTTCCAAGCAGTATCCAGGCTACATTCTCTCACGAATGTTGGAATTTACCAATGATACGAAGTTGA
CCAGACCTGCTTTACAAGAACACGGAACTTTGATGCTTCCGCTTGCGGCAATCGAGGAGCTTAGGAAGGTTCCGACAGTA
TGA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-234)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus pneumoniae Rx1

52.049

100

0.529
  mecA Streptococcus pneumoniae D39

52.049

100

0.529
  mecA Streptococcus pneumoniae R6

52.049

100

0.529
  mecA Streptococcus pneumoniae TIGR4

52.049

100

0.529
  mecA Streptococcus mutans UA159

50.41

100

0.513
  mecA Streptococcus thermophilus LMD-9

47.917

100

0.479
  mecA Streptococcus thermophilus LMG 18311

47.5

100

0.475

Multiple sequence alignment