Detailed information    

insolico Bioinformatically predicted

Overview

Name   stkP   Type   Regulator
Locus tag   DP112_RS02155 Genome accession   NZ_CP030125
Coordinates   413148..415142 (+) Length   664 a.a.
NCBI ID   WP_114866239.1    Uniprot ID   -
Organism   Streptococcus suis strain HA1003     
Function   require for competence development; phosphorylate ComE (predicted from homology)   
Competence regulation

Genomic Context

Location: 408148..420142
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DP112_RS02140 (DP112_02140) fmt 410135..411073 (+) 939 WP_114866238.1 methionyl-tRNA formyltransferase -
  DP112_RS02145 (DP112_02145) rsmB 411060..412373 (+) 1314 WP_105135494.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  DP112_RS02150 (DP112_02150) - 412411..413148 (+) 738 WP_004194145.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  DP112_RS02155 (DP112_02155) stkP 413148..415142 (+) 1995 WP_114866239.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  DP112_RS02160 (DP112_02160) liaF 415431..416126 (+) 696 WP_105135492.1 cell wall-active antibiotics response protein LiaF -
  DP112_RS02165 (DP112_02165) - 416123..417139 (+) 1017 WP_002937028.1 sensor histidine kinase -
  DP112_RS02170 (DP112_02170) - 417111..417752 (+) 642 WP_002937025.1 response regulator transcription factor -
  DP112_RS02175 (DP112_02175) - 417802..419202 (+) 1401 WP_024377222.1 Cof-type HAD-IIB family hydrolase -
  DP112_RS02180 (DP112_02180) - 419204..419575 (+) 372 WP_002937017.1 S1 RNA-binding domain-containing protein -

Sequence

Protein


Download         Length: 664 a.a.        Molecular weight: 71353.94 Da        Isoelectric Point: 6.3005

>NTDB_id=299475 DP112_RS02155 WP_114866239.1 413148..415142(+) (stkP) [Streptococcus suis strain HA1003]
MIQIGKIFAGRYRIVRQIGRGGMADVYLARDLILDGEEVAVKVLRTNYQTDQIAIQRFQREARAMAELDHPNIVRISDIG
EEDGQQYLAMEYVNGLDLKRYIKENAPLSNDVAVRIMGQILLAMRMAHTRGIVHRDLKPQNVLLTSNGVAKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATIQSDIYAMGIILFEMLTGRIPYDGDSAVTIALQHFQKPLPSVREENANVP
QALENVVLKATAKKLNERYKSVAEMYADLASALSMDRRNEPRVELEGNKVDTKTLPKLSQANVETKVPHTNSSAQVSATD
KGSGKKEVAKSGNKPVSKPRLGMRTRYKVLIGAVLLTVIAAGLIFFNTPRTVTVPDVSGQTVEKATEMIEVAGLEVGNIT
EEATATVDEGLVIRTSPAAKTTRRQGSKIDIVVAMAAMVSIPDVTDKDSDTARQDLEALGFQVTIKEEYSEKVAQGLVIK
TDPGANSSAEKGAKITLYVSKGVAPQVVPNVVGKTQENATQILQAAGFSIGTITQEYSSSVTAGQVISTDPVANTELTKG
SIINLVVSKGKELIMPDLTSGNYTYSQARSQLQALGVNVESIEKQEDRSYYSTTSDIVIGQYPAAGATIDGTVTLYVSVA
STGTSSDSSTGSSTSTSTSTDSGQ

Nucleotide


Download         Length: 1995 bp        

>NTDB_id=299475 DP112_RS02155 WP_114866239.1 413148..415142(+) (stkP) [Streptococcus suis strain HA1003]
ATGATTCAAATCGGTAAGATCTTTGCCGGTCGGTATCGAATCGTTCGGCAAATTGGTCGAGGCGGTATGGCAGATGTTTA
CCTAGCAAGAGATTTGATTTTAGATGGAGAAGAGGTTGCCGTTAAAGTTCTTCGGACCAACTATCAGACAGATCAAATTG
CTATCCAGCGTTTTCAACGTGAAGCGCGTGCCATGGCAGAACTTGACCATCCCAATATCGTTCGTATTTCGGACATCGGC
GAAGAAGATGGTCAACAGTATCTGGCTATGGAATATGTCAATGGCCTCGATTTAAAACGTTATATAAAAGAAAATGCACC
ACTCTCCAACGATGTTGCGGTGCGAATTATGGGACAGATTCTCCTTGCTATGCGAATGGCGCACACGAGAGGAATTGTCC
ATCGAGATTTGAAACCTCAGAACGTCCTTTTGACTTCCAATGGAGTCGCTAAAGTAACAGACTTTGGTATTGCAGTTGCC
TTTGCTGAAACGAGTTTGACACAAACCAACTCCATGTTGGGTTCTGTTCACTATCTTTCACCTGAGCAGGCGCGTGGTTC
GAAAGCTACCATTCAAAGTGACATTTATGCGATGGGAATCATCCTTTTTGAAATGTTGACGGGTCGCATTCCCTATGATG
GAGACAGTGCTGTGACGATTGCTCTTCAGCATTTCCAAAAACCTCTCCCATCTGTTAGAGAAGAGAATGCCAATGTACCT
CAGGCTTTAGAAAATGTTGTACTAAAAGCAACGGCTAAAAAATTAAACGAGCGCTATAAGTCGGTTGCAGAAATGTATGC
AGATTTAGCTTCGGCCCTATCCATGGATCGTCGGAATGAACCTAGGGTTGAACTAGAAGGGAACAAGGTTGATACAAAAA
CCTTGCCGAAACTCTCCCAGGCCAATGTTGAAACGAAAGTACCGCATACAAACAGTTCTGCCCAAGTTTCTGCGACGGAT
AAGGGGTCTGGTAAGAAAGAAGTGGCGAAGTCGGGAAATAAGCCTGTTTCAAAACCAAGGTTAGGTATGCGTACACGCTA
CAAAGTCTTGATAGGAGCTGTTTTGTTAACAGTCATAGCGGCTGGACTCATATTTTTCAACACTCCACGAACAGTTACCG
TTCCTGATGTATCTGGTCAAACCGTTGAAAAAGCTACAGAAATGATTGAAGTGGCAGGATTGGAAGTTGGAAACATCACA
GAAGAAGCGACAGCGACTGTAGATGAAGGCTTGGTAATACGGACCTCTCCGGCTGCAAAGACGACCAGACGTCAAGGAAG
TAAGATTGATATTGTAGTAGCAATGGCTGCGATGGTATCTATTCCAGATGTGACAGATAAGGATTCTGATACTGCACGGC
AGGACTTGGAGGCTCTTGGTTTCCAAGTGACAATAAAAGAAGAATATAGCGAAAAAGTTGCCCAAGGTCTCGTTATCAAA
ACAGATCCAGGAGCAAATAGTTCTGCTGAGAAGGGGGCAAAAATTACCCTTTACGTTTCCAAAGGAGTAGCGCCACAAGT
TGTTCCAAACGTTGTTGGAAAAACTCAGGAGAATGCTACTCAAATTCTTCAGGCAGCAGGCTTCAGTATTGGAACTATCA
CTCAGGAATATAGCTCATCTGTTACTGCGGGTCAGGTTATCAGTACAGATCCTGTTGCCAATACAGAGTTGACAAAAGGT
TCTATCATCAATCTAGTTGTTTCAAAAGGAAAAGAATTGATTATGCCTGATTTAACATCTGGCAATTACACCTATTCACA
GGCACGTAGTCAATTACAAGCACTGGGTGTCAATGTGGAAAGTATTGAAAAACAAGAAGATAGAAGCTATTATTCAACGA
CAAGTGACATCGTCATTGGACAATATCCTGCTGCTGGCGCAACAATTGATGGAACAGTTACCTTGTATGTCTCCGTTGCA
TCAACCGGCACCAGTAGCGATTCCTCAACAGGAAGCTCCACTAGCACAAGTACTTCGACAGATAGCGGACAATAA

Domains

Predicted by InterproScan.

Protein kinase domain (Pkinase)

(12-240)

PASTA domain (PASTA)

(440-501)

PASTA domain (PASTA)

(507-569)

PASTA domain (PASTA)

(574-638)

PASTA domain (PASTA)

(372-433)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  stkP Streptococcus pneumoniae TIGR4

53.086

97.59

0.518
  stkP/pknB Streptococcus salivarius strain HSISS4

51.839

90.06

0.467
  pknB Streptococcus mutans UA159

55.083

81.476

0.449
  stkP Streptococcus pneumoniae D39

67.963

65.813

0.447
  stkP Streptococcus pneumoniae R6

67.963

65.813

0.447
  stkP Streptococcus pneumoniae Rx1

67.735

65.813

0.446

Multiple sequence alignment