Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   DK875_RS01885 Genome accession   NZ_CP030020
Coordinates   361235..361957 (+) Length   240 a.a.
NCBI ID   WP_002938171.1    Uniprot ID   A0A116M1G6
Organism   Streptococcus suis strain ISU2514     
Function   degradation of ComW (predicted from homology)   
Competence regulation

Genomic Context

Location: 356235..366957
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DK875_RS01860 (DK875_01945) - 356519..357421 (+) 903 WP_002937414.1 SPFH domain-containing protein -
  DK875_RS01865 (DK875_01950) - 357507..357716 (+) 210 WP_009910800.1 hypothetical protein -
  DK875_RS01870 (DK875_01955) - 357843..358586 (-) 744 WP_024389055.1 amino acid ABC transporter ATP-binding protein -
  DK875_RS01875 (DK875_01960) - 358579..360144 (-) 1566 WP_024394234.1 ABC transporter substrate-binding protein/permease -
  DK875_RS01880 (DK875_01965) - 360271..361107 (+) 837 WP_002938173.1 undecaprenyl-diphosphate phosphatase -
  DK875_RS01885 (DK875_01970) mecA 361235..361957 (+) 723 WP_002938171.1 adaptor protein MecA Regulator
  DK875_RS01890 (DK875_01975) - 361954..363126 (+) 1173 WP_002938168.1 glycosyltransferase family 4 protein -
  DK875_RS01895 (DK875_01980) sufC 363606..364379 (+) 774 WP_002938165.1 Fe-S cluster assembly ATPase SufC -
  DK875_RS01900 (DK875_01985) sufD 364396..365658 (+) 1263 WP_002938159.1 Fe-S cluster assembly protein SufD -
  DK875_RS01905 (DK875_01990) - 365660..366886 (+) 1227 WP_002938158.1 cysteine desulfurase -

Sequence

Protein


Download         Length: 240 a.a.        Molecular weight: 27973.51 Da        Isoelectric Point: 4.0497

>NTDB_id=298354 DK875_RS01885 WP_002938171.1 361235..361957(+) (mecA) [Streptococcus suis strain ISU2514]
MKVKQISDSTLKITIKLDDLEERGMELSDFLIPQEKTEEFFYTVLDELDLPMTFRESGMLSFRVTPKPDRVDIFVTKSDL
DQSLNFDEFTDLSELGDVASMTPDEFFKSLEQTVREKSAPDATAVRHLEEVEQEEEADEEEQERYIYYILEFPTIEDLFT
FVGTVDYPVEESELYKMDGHYYLTVLINVENRSKQYPGYILSRMLEFTNDTKLTRPALQEHGTLMLPLAAIEELRKVPTV

Nucleotide


Download         Length: 723 bp        

>NTDB_id=298354 DK875_RS01885 WP_002938171.1 361235..361957(+) (mecA) [Streptococcus suis strain ISU2514]
ATGAAAGTAAAGCAAATTAGTGATTCAACCTTGAAAATCACTATAAAATTAGATGATTTGGAAGAGAGAGGAATGGAACT
TTCGGACTTTCTCATTCCGCAAGAAAAGACAGAGGAGTTCTTCTATACTGTTTTGGATGAATTGGATTTACCAATGACTT
TCCGAGAAAGCGGTATGTTGAGTTTTCGTGTGACTCCGAAGCCAGATCGGGTGGACATCTTTGTTACCAAATCTGATTTG
GATCAGAGCTTGAATTTCGATGAATTTACAGATTTGTCGGAACTTGGTGATGTCGCAAGTATGACTCCAGATGAGTTTTT
CAAGAGTTTGGAGCAAACCGTTCGTGAGAAAAGCGCACCGGATGCAACAGCCGTTCGTCATTTGGAAGAGGTAGAGCAAG
AGGAAGAAGCAGATGAAGAGGAGCAGGAGCGCTATATTTACTATATTTTGGAATTTCCAACGATAGAGGATCTGTTTACT
TTTGTTGGTACGGTTGATTATCCAGTAGAAGAATCGGAATTATATAAAATGGATGGTCACTACTACTTGACCGTTCTTAT
CAATGTAGAAAATCGTTCCAAGCAGTATCCAGGCTACATTCTCTCAAGAATGTTGGAATTTACCAATGATACTAAGTTGA
CCAGACCTGCTTTACAAGAACACGGAACTTTGATGCTTCCGCTTGCGGCAATCGAGGAGCTTAGGAAGGTTCCGACAGTA
TGA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-234)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A116M1G6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus pneumoniae Rx1

51.639

100

0.525
  mecA Streptococcus pneumoniae D39

51.639

100

0.525
  mecA Streptococcus pneumoniae R6

51.639

100

0.525
  mecA Streptococcus pneumoniae TIGR4

51.639

100

0.525
  mecA Streptococcus mutans UA159

50

100

0.508
  mecA Streptococcus thermophilus LMD-9

47.5

100

0.475
  mecA Streptococcus thermophilus LMG 18311

47.083

100

0.471

Multiple sequence alignment