Detailed information    

insolico Bioinformatically predicted

Overview

Name   stkP   Type   Regulator
Locus tag   DK235_RS02045 Genome accession   NZ_CP030017
Coordinates   409811..411805 (+) Length   664 a.a.
NCBI ID   WP_011921992.1    Uniprot ID   -
Organism   Streptococcus suis strain ISU1606     
Function   require for competence development; phosphorylate ComE (predicted from homology)   
Competence regulation

Genomic Context

Location: 404811..416805
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DK235_RS02030 (DK235_02120) fmt 406798..407736 (+) 939 WP_011921989.1 methionyl-tRNA formyltransferase -
  DK235_RS02035 (DK235_02125) rsmB 407723..409036 (+) 1314 WP_011921990.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  DK235_RS02040 (DK235_02130) - 409074..409811 (+) 738 WP_012774983.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  DK235_RS02045 (DK235_02135) stkP 409811..411805 (+) 1995 WP_011921992.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  DK235_RS02050 (DK235_02140) liaF 412226..412921 (+) 696 WP_012774984.1 cell wall-active antibiotics response protein LiaF -
  DK235_RS02055 (DK235_02145) - 412918..413934 (+) 1017 WP_002937028.1 sensor histidine kinase -
  DK235_RS02060 (DK235_02150) - 413906..414547 (+) 642 WP_002937025.1 response regulator transcription factor -
  DK235_RS02065 (DK235_02155) - 414597..415997 (+) 1401 WP_011921996.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  DK235_RS02070 (DK235_02160) - 415999..416370 (+) 372 WP_011921997.1 S1 RNA-binding domain-containing protein -

Sequence

Protein


Download         Length: 664 a.a.        Molecular weight: 71256.79 Da        Isoelectric Point: 6.5350

>NTDB_id=298311 DK235_RS02045 WP_011921992.1 409811..411805(+) (stkP) [Streptococcus suis strain ISU1606]
MIQIGKIFAGRYRIVRQIGRGGMADVYLARDLILDGEEVAVKVLRTNYQTDQIAIQRFQREARAMAELDHPNIVRISDIG
EEDGQQYLAMEYVNGLDLKRYIKENAPLSNDVAVRIMGQILLAMRMAHTRGIVHRDLKPQNVLLTSNGVAKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATIQSDIYAMGIILFEMLTGRIPYDGDSAVTIALQHFQKPLPSVREENANVP
QALENVVLKATAKKLNERYKSVAEMYADLASALSMDRQNEPRVELEGNKVDTKTLPKLSQANVETKVPHTNSSAQVSATD
KGSGKKEVAKSGNKPVSKPRPGIRTRYKVLIGAILLTVIAAGLMFFNTPRTVTVPDVSGQTVEKATEMIEVAGLEVGNIT
EEATATVDEGLVIRTSPAAKTTRRQGSKIDIVVATAALASIPDVVDKESDTARQELEALGFQVTIKEEYSEKVAQGLVIK
TDPGANSSAEKGAKITLYVSKGVAPQVVPNVVGKSQENATQILQTAGFSIGTITQEYSSSVTAGQVISTDPVANTELAKG
SIINLVISKGKELIMPDLTSGNYTYSQARSQLQALGVNAESIEKQEDRSYYSTTSDIVIGQYPAAGATIDGTVTLYVSVA
STRTSSDSSAGSSTSTSTSTGSGQ

Nucleotide


Download         Length: 1995 bp        

>NTDB_id=298311 DK235_RS02045 WP_011921992.1 409811..411805(+) (stkP) [Streptococcus suis strain ISU1606]
ATGATTCAAATCGGTAAGATCTTTGCCGGTCGGTATCGAATCGTTCGGCAAATTGGTCGAGGCGGTATGGCAGATGTTTA
CCTAGCAAGAGATTTGATTTTAGATGGAGAAGAGGTTGCTGTTAAAGTTCTTCGGACCAACTATCAGACAGATCAAATTG
CTATCCAGCGTTTTCAACGTGAAGCGCGTGCCATGGCAGAACTTGACCATCCCAATATCGTTCGTATTTCGGACATCGGT
GAAGAAGATGGTCAACAGTATCTGGCTATGGAATATGTCAATGGCCTCGATTTAAAACGTTATATAAAAGAAAATGCACC
ACTTTCCAACGATGTTGCGGTGCGAATTATGGGACAGATTCTCCTTGCTATGCGCATGGCGCACACGAGAGGAATTGTCC
ATCGAGATTTGAAACCTCAGAACGTCCTTTTGACTTCCAATGGAGTCGCTAAAGTAACAGACTTTGGTATTGCAGTTGCC
TTTGCTGAAACGAGTTTGACACAAACCAACTCCATGTTGGGTTCTGTTCACTATCTTTCACCTGAGCAGGCGCGTGGTTC
GAAAGCGACCATTCAAAGTGATATTTATGCGATGGGAATCATCCTTTTTGAAATGTTGACGGGTCGCATTCCCTATGATG
GAGACAGTGCTGTGACGATCGCTCTTCAGCATTTCCAAAAACCTCTCCCATCTGTTAGAGAAGAGAATGCCAACGTACCT
CAGGCCTTAGAAAATGTTGTACTAAAAGCAACGGCAAAAAAATTAAACGAGCGCTATAAGTCGGTTGCAGAAATGTATGC
AGATTTAGCTTCGGCTCTATCCATGGATCGTCAGAATGAACCCAGGGTTGAACTAGAAGGGAACAAGGTTGATACAAAAA
CCTTGCCGAAACTCTCCCAAGCCAATGTTGAAACGAAAGTACCGCATACAAACAGTTCTGCTCAAGTTTCTGCGACGGAT
AAGGGGTCTGGTAAGAAAGAAGTGGCGAAGTCGGGAAATAAGCCTGTTTCAAAACCAAGGCCAGGCATACGTACACGCTA
CAAAGTCTTGATAGGAGCTATTTTGTTAACAGTCATAGCGGCTGGACTCATGTTTTTCAACACTCCACGAACAGTTACAG
TCCCTGATGTATCTGGTCAAACCGTTGAAAAAGCTACAGAAATGATTGAAGTGGCAGGATTGGAAGTTGGAAATATCACA
GAAGAAGCGACAGCGACTGTAGATGAAGGCTTGGTAATACGGACCTCTCCGGCTGCAAAGACGACCAGACGTCAAGGGAG
TAAGATTGATATTGTAGTAGCAACGGCTGCGCTGGCATCTATTCCAGATGTGGTGGATAAGGAGTCTGATACTGCGCGGC
AGGAATTGGAGGCCCTTGGTTTCCAAGTGACAATAAAAGAAGAATATAGCGAAAAAGTTGCCCAAGGACTCGTTATCAAA
ACAGATCCAGGAGCAAATAGTTCTGCTGAGAAGGGTGCAAAAATTACCCTTTACGTTTCCAAAGGAGTGGCGCCACAAGT
TGTTCCAAACGTTGTTGGAAAAAGTCAGGAGAATGCTACTCAAATTCTTCAGACAGCAGGCTTCAGCATTGGAACCATTA
CTCAGGAATATAGCTCATCTGTTACTGCAGGTCAGGTTATCAGCACAGATCCCGTTGCCAATACAGAGTTGGCAAAAGGT
TCTATCATCAATCTAGTTATTTCAAAAGGAAAAGAATTGATTATGCCTGATTTAACATCTGGCAATTACACCTATTCACA
GGCGCGTAGTCAATTACAAGCCTTGGGTGTCAATGCGGAAAGTATTGAAAAACAAGAAGATAGAAGCTATTATTCAACGA
CAAGTGACATCGTCATTGGACAATATCCTGCTGCTGGAGCAACAATTGATGGAACAGTTACCTTGTATGTCTCTGTTGCA
TCAACCAGAACCAGTAGCGATTCTTCAGCAGGAAGTTCCACAAGTACAAGTACTTCAACAGGTAGCGGACAATAA

Domains

Predicted by InterproScan.

PASTA domain (PASTA)

(574-638)

PASTA domain (PASTA)

(372-434)

PASTA domain (PASTA)

(507-569)

PASTA domain (PASTA)

(441-501)

Protein kinase domain (Pkinase)

(12-240)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  stkP Streptococcus pneumoniae TIGR4

52.18

100

0.523
  stkP Streptococcus pneumoniae D39

52.18

100

0.523
  stkP Streptococcus pneumoniae R6

52.18

100

0.523
  stkP Streptococcus pneumoniae Rx1

52.03

100

0.521
  stkP/pknB Streptococcus salivarius strain HSISS4

51.171

90.06

0.461
  pknB Streptococcus mutans UA159

54.529

81.476

0.444

Multiple sequence alignment