Detailed information NTG0298291

Bioinformatically predicted

Overview

• Name: htrA
• Type: Regulator
• Locus tag: A7J09_RS12285
• Genome accession: NZ_CP030015
• Coordinates: 2561630..2562826 (+)
• Length: 398 a.a.
• NCBI ID: WP_024387292.1
• Uniprot ID: -
• Organism: Streptococcus suis strain ISU2812
• Function: require for competence development (predicted from homology) Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
IS/Tn	2559496..2560698	2561630..2562826	flank	932

Gene organization within MGE regions

Location: 2559496..2562826

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
A7J09_RS12275 (A7J09_12520)	-	2559496..2560698 (-)	1203	WP_148124345.1	IS110 family transposase	-
A7J09_RS12280 (A7J09_12525)	rlmH	2560976..2561455 (-)	480	WP_023371894.1	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH	-
A7J09_RS12285 (A7J09_12530)	htrA	2561630..2562826 (+)	1197	WP_024387292.1	S1C family serine protease	Regulator

Sequence

Protein

• Length: 398 a.a.
• Molecular weight: 41818.83 Da
• Isoelectric Point: 4.5940

>NTDB_id=298291 A7J09_RS12285 WP_024387292.1 2561630..2562826(+) (htrA) [Streptococcus suis strain ISU2812]
MERIPYMKKYLKFAILFVIGFFGGLIGALSASFFQPQVQQANSAITSVSNVQYNNETSTTKAVEKVQNAVVSVINYQKSA
NNSLGVIFGNIESSDELAVAGEGSGVIYKKDGQYAYIVTNTHVINNAEKIDILLASGEKISGELVGSDTYSDIAVIKISA
DKVTAVAEFADSDTIKVGETAIAIGSPLGSVYANTVTQGIISSLSRTVTSQSKDGQTISTNAIQTDTAINPGNSGGPLIN
TQGQVIGITSSKITSSSANSSGVAVEGLGFAIPANDAVAIINQLEKTGQVSRPALGVHMVNLTTLSTSQLEKAGLSNTEL
TSGVVIVSTQSGLPADGKLETFDVITEIDGEAIQNKSDLQSALYKHQIGDTITVTYYRNNQKQTVDIKLTHSTEELSE

Nucleotide

• Length: 1197 bp

>NTDB_id=298291 A7J09_RS12285 WP_024387292.1 2561630..2562826(+) (htrA) [Streptococcus suis strain ISU2812]
ATGGAAAGGATTCCTTATATGAAAAAATATTTGAAATTTGCGATTTTATTTGTAATTGGATTTTTTGGGGGTCTTATCGG
GGCCTTATCAGCCTCTTTCTTCCAACCACAGGTGCAACAAGCAAATTCTGCTATCACTAGTGTCAGCAATGTTCAATATA
ATAATGAAACTTCCACCACAAAAGCTGTAGAGAAAGTACAAAATGCTGTTGTGTCTGTTATTAATTACCAAAAATCAGCC
AACAATAGTCTTGGTGTTATCTTTGGAAATATTGAATCATCTGACGAACTAGCTGTTGCTGGAGAGGGGTCTGGGGTTAT
CTATAAAAAAGATGGTCAATATGCCTATATTGTGACAAATACGCATGTTATTAATAACGCAGAAAAGATTGATATCCTTT
TAGCATCTGGAGAAAAAATTAGCGGTGAACTTGTTGGTTCCGATACCTATTCTGATATAGCTGTTATAAAAATATCAGCA
GATAAAGTCACTGCTGTTGCTGAATTTGCTGATTCCGATACAATTAAAGTTGGAGAAACTGCTATCGCAATTGGTAGTCC
TCTAGGTAGCGTCTACGCCAATACAGTTACCCAGGGTATTATTTCTAGCTTAAGTCGGACAGTTACTTCACAATCAAAAG
ATGGACAAACAATCTCAACTAACGCTATTCAAACTGATACAGCTATCAACCCTGGAAACTCTGGCGGACCGTTAATCAAT
ACCCAAGGACAAGTGATAGGCATTACCTCTAGCAAAATTACCTCAAGTTCTGCAAATAGCTCAGGCGTGGCTGTAGAAGG
GTTGGGATTTGCTATTCCTGCAAATGATGCCGTAGCTATTATCAATCAGCTTGAAAAAACTGGACAAGTTAGCCGACCTG
CTCTTGGAGTTCATATGGTTAACTTGACGACCTTGTCAACTAGTCAATTAGAAAAAGCTGGATTATCAAATACGGAATTA
ACATCTGGTGTTGTAATTGTCTCTACACAAAGTGGACTACCTGCAGATGGAAAATTAGAAACTTTTGATGTCATTACTGA
GATTGACGGAGAAGCTATTCAAAATAAGAGTGATCTCCAAAGTGCTCTCTACAAACATCAAATTGGAGACACAATCACTG
TAACTTATTACCGCAATAATCAGAAACAAACTGTTGACATTAAGTTGACACATTCTACAGAAGAACTTAGCGAATAA

Domains

Predicted by InterproScan.

• Trypsin-like peptidase domain (Trypsin_2) (103-248)

• PDZ domain (PDZ_2) (293-389)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
htrA	Streptococcus mutans UA159	59.446	99.749	0.593
htrA	Streptococcus gordonii str. Challis substr. CH1	59.241	99.246	0.588
htrA	Streptococcus pneumoniae D39	57.252	98.744	0.565
htrA	Streptococcus pneumoniae TIGR4	57.252	98.744	0.565
htrA	Streptococcus mitis NCTC 12261	57.252	98.744	0.565
htrA	Streptococcus pneumoniae R6	57.252	98.744	0.565
htrA	Streptococcus pneumoniae Rx1	57.252	98.744	0.565