Detailed information    

insolico Bioinformatically predicted

Overview

Name   comR   Type   Regulator
Locus tag   A7J09_RS00370 Genome accession   NZ_CP030015
Coordinates   68388..69290 (+) Length   300 a.a.
NCBI ID   WP_024399278.1    Uniprot ID   A0A0M9FKU5
Organism   Streptococcus suis strain ISU2812     
Function   activate transcription of comX (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
IS/Tn 66842..68296 68388..69290 flank 92


Gene organization within MGE regions


Location: 66842..69290
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A7J09_RS00365 (A7J09_00365) - 66842..68296 (+) 1455 WP_074411018.1 IS1182 family transposase -
  A7J09_RS00370 (A7J09_00370) comR 68388..69290 (+) 903 WP_024399278.1 helix-turn-helix domain-containing protein Regulator

Sequence

Protein


Download         Length: 300 a.a.        Molecular weight: 35179.23 Da        Isoelectric Point: 4.3840

>NTDB_id=298242 A7J09_RS00370 WP_024399278.1 68388..69290(+) (comR) [Streptococcus suis strain ISU2812]
MNDKEFGQRVRQLRETASLTREQFCDDELELSVRQLTRIEAGTSKPTFSKIQYIATRLGMGLYELMPDYVSLPERYSKLK
FDVLRTPTYENEELMGKRADMMTEIYDDYYDDLPEEEKIAIDAIQSIIDVFETKTAEFGQDILEDYFEQIQRKPQFSAND
LLIIQLYLINLRMEVKQSSDFQHFLDLVEKLPSQVELVESGDLFILRDVMITSVGLLGQKEEFSYIPTLFEALDKIMQKT
QDFQKKPILNLLKWKYELLINKDKDAATALYEEALLFARIIGNAHLTAKLEEEWRKDSQL

Nucleotide


Download         Length: 903 bp        

>NTDB_id=298242 A7J09_RS00370 WP_024399278.1 68388..69290(+) (comR) [Streptococcus suis strain ISU2812]
ATGAACGATAAGGAATTTGGACAACGTGTACGTCAACTTCGAGAAACCGCTAGTCTGACACGTGAACAGTTTTGCGATGA
CGAACTTGAGCTCTCCGTCCGCCAACTAACCCGTATCGAAGCAGGTACTTCTAAGCCGACTTTTTCAAAAATCCAGTATA
TCGCAACCCGCTTAGGCATGGGGCTCTATGAGCTTATGCCTGATTATGTGTCGCTACCTGAACGATATTCCAAACTGAAG
TTTGATGTACTTCGTACACCGACTTATGAAAATGAGGAATTGATGGGAAAACGGGCAGATATGATGACGGAAATCTATGA
TGATTATTACGACGACTTGCCTGAGGAGGAGAAAATAGCGATTGATGCCATTCAATCTATTATTGATGTATTTGAAACGA
AGACAGCAGAATTTGGTCAAGATATTCTAGAAGATTATTTTGAACAAATCCAAAGAAAACCCCAATTTTCAGCCAACGAT
TTGTTGATAATCCAGCTCTATTTAATCAATTTGAGAATGGAAGTTAAACAGAGTAGTGATTTTCAGCACTTTTTAGACTT
GGTGGAAAAGTTACCAAGCCAAGTAGAATTAGTTGAATCTGGGGATTTGTTTATTTTAAGGGATGTGATGATAACTTCTG
TTGGACTTTTGGGACAAAAGGAAGAATTTAGCTATATTCCTACACTCTTTGAAGCACTTGATAAGATAATGCAGAAGACC
CAAGATTTTCAAAAGAAACCTATTCTTAATCTGCTTAAGTGGAAATATGAGTTGTTAATAAATAAAGATAAAGATGCTGC
AACTGCCTTATATGAAGAAGCACTTCTTTTTGCAAGAATAATTGGTAATGCCCACCTAACGGCTAAATTAGAAGAAGAGT
GGAGAAAAGATAGTCAATTATAG

Domains

Predicted by InterproScan.

ComR tetratricopeptide (ComR_TPR)

(73-294)

Helix-turn-helix domain (HTH_31)

(5-60)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0M9FKU5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comR Streptococcus suis P1/7

67.224

99.667

0.67
  comR Streptococcus suis 05ZYH33

67.224

99.667

0.67
  comR Streptococcus suis D9

61.13

100

0.613
  comR Streptococcus mutans UA159

43.478

99.667

0.433
  comR Streptococcus pyogenes MGAS8232

40.203

98.667

0.397
  comR Streptococcus infantarius subsp. infantarius ATCC BAA-102

40.69

96.667

0.393

Multiple sequence alignment