Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Regulator
Locus tag   EQH20_RS05730 Genome accession   NZ_CP035260
Coordinates   1165805..1166344 (-) Length   179 a.a.
NCBI ID   WP_225353592.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain TVO_1901925     
Function   processing and transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 1160805..1171344
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EQH20_RS05700 (EQH20_06005) - 1161059..1161994 (+) 936 WP_061647412.1 bifunctional oligoribonuclease/PAP phosphatase NrnA -
  EQH20_RS05705 (EQH20_06010) - 1162090..1162332 (+) 243 WP_000710764.1 type B 50S ribosomal protein L31 -
  EQH20_RS05710 (EQH20_06015) - 1162389..1162607 (-) 219 WP_000028151.1 hypothetical protein -
  EQH20_RS05715 (EQH20_06020) - 1162604..1163171 (-) 568 Protein_1141 transposase -
  EQH20_RS05720 (EQH20_06025) gdhA 1163714..1165060 (+) 1347 WP_000199560.1 NADP-specific glutamate dehydrogenase -
  EQH20_RS05725 (EQH20_06035) - 1165566..1165736 (-) 171 WP_000711943.1 hypothetical protein -
  EQH20_RS05730 (EQH20_06040) comA 1165805..1166344 (-) 540 WP_225353592.1 ATP-binding cassette domain-containing protein Regulator
  EQH20_RS05735 (EQH20_06045) - 1166370..1167176 (-) 807 Protein_1145 transposase family protein -
  EQH20_RS05740 (EQH20_06055) - 1167558..1168253 (+) 696 Protein_1146 IS630 family transposase -
  EQH20_RS05745 (EQH20_06060) - 1168487..1168939 (-) 453 Protein_1147 hypothetical protein -
  EQH20_RS05750 (EQH20_06065) - 1168941..1169228 (-) 288 WP_000869754.1 hypothetical protein -
  EQH20_RS05755 (EQH20_06070) - 1169585..1170904 (-) 1320 WP_050118396.1 FtsX-like permease family protein -

Sequence

Protein


Download         Length: 179 a.a.        Molecular weight: 19891.09 Da        Isoelectric Point: 7.2433

>NTDB_id=297449 EQH20_RS05730 WP_225353592.1 1165805..1166344(-) (comA) [Streptococcus pneumoniae strain TVO_1901925]
MLSRLYKIDTGKVLFDGVNINQIDKKILSQNLGVVPQDSFLLNRSILDNITLKHEVTSQKIEEVCKAVQIYDEITAMPMK
FNTIISEMGSNISGGQRQRIALARALINNPSIVILDEATSALDTINEERITKYIQSQGCTQIIIAHRLSTIKDADIIFVM
KGGKIVESGNHKYLMDLGG

Nucleotide


Download         Length: 540 bp        

>NTDB_id=297449 EQH20_RS05730 WP_225353592.1 1165805..1166344(-) (comA) [Streptococcus pneumoniae strain TVO_1901925]
ATACTATCAAGATTATATAAGATTGATACAGGAAAAGTTTTATTTGATGGTGTAAATATTAATCAAATAGATAAAAAAAT
ATTAAGTCAAAATTTAGGAGTAGTTCCACAGGATTCGTTTTTATTGAACAGAAGTATTCTTGATAACATAACTTTAAAGC
ACGAAGTTACTTCACAAAAGATAGAGGAAGTTTGTAAAGCAGTTCAAATCTATGATGAAATCACGGCTATGCCGATGAAA
TTTAATACTATCATCTCAGAGATGGGGTCAAATATTTCAGGTGGGCAAAGGCAACGGATAGCACTGGCACGTGCATTAAT
AAATAATCCTAGTATTGTAATTTTAGATGAAGCAACTAGTGCATTAGACACTATTAATGAGGAAAGAATAACAAAGTATA
TACAAAGTCAGGGTTGTACTCAAATAATTATAGCTCATAGATTGTCAACGATTAAGGATGCGGATATTATTTTTGTAATG
AAAGGTGGTAAGATTGTTGAGTCAGGAAATCATAAGTACTTAATGGATCTTGGTGGATAG

Domains

Predicted by InterProScan.

ABC transporter (ABC_tran)

(1-120)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Streptococcus gordonii str. Challis substr. CH1

42.077

100

0.43
  comA Streptococcus mitis NCTC 12261

42.541

100

0.43
  comA Streptococcus mitis SK321

41.989

100

0.425
  comA Streptococcus pneumoniae R6

41.436

100

0.419
  comA Streptococcus pneumoniae Rx1

41.436

100

0.419
  comA Streptococcus pneumoniae D39

41.436

100

0.419
  comA/nlmT Streptococcus mutans UA159

41.011

99.441

0.408
  comA Streptococcus pneumoniae TIGR4

40.331

100

0.408
  rcrQ Streptococcus mutans UA159

37.158

100

0.38