Detailed information NTG0297210

Bioinformatically predicted

Overview

• Name: comA
• Type: Regulator
• Locus tag: EQH22_RS06045
• Genome accession: NZ_CP035258
• Coordinates: 1216450..1217091 (-)
• Length: 213 a.a.
• NCBI ID: WP_000151459.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain TVO_1901927
• Function: processing and transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 1211450..1222091

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EQH22_RS06020 (EQH22_06315)	-	1212412..1212654 (+)	243	WP_000710767.1	type B 50S ribosomal protein L31	-
EQH22_RS06025 (EQH22_06320)	-	1212711..1212929 (-)	219	WP_001810998.1	hypothetical protein	-
EQH22_RS06030 (EQH22_06325)	-	1212926..1213877 (-)	952	Protein_1213	IS630 family transposase	-
EQH22_RS06035 (EQH22_06330)	gdhA	1214421..1215771 (+)	1351	Protein_1214	NADP-specific glutamate dehydrogenase	-
EQH22_RS06040 (EQH22_06340)	-	1216267..1216437 (-)	171	WP_000711939.1	hypothetical protein	-
EQH22_RS06045 (EQH22_06345)	comA	1216450..1217091 (-)	642	WP_000151459.1	ATP-binding cassette domain-containing protein	Regulator
EQH22_RS11025 (EQH22_06350)	-	1217216..1217402 (-)	187	Protein_1217	hypothetical protein	-
EQH22_RS06050 (EQH22_06355)	-	1217363..1217881 (+)	519	WP_001811001.1	transposase	-
EQH22_RS06055 (EQH22_06360)	-	1218102..1218296 (-)	195	Protein_1219	ROK family protein	-
EQH22_RS06060 (EQH22_06365)	-	1218323..1219240 (-)	918	Protein_1220	dihydrodipicolinate synthase family protein	-
EQH22_RS06065 (EQH22_06370)	-	1219272..1219679 (-)	408	WP_000216067.1	cytidine deaminase	-
EQH22_RS06070 (EQH22_06375)	-	1219967..1220455 (-)	489	WP_000872894.1	phosphatidylglycerophosphatase A	-
EQH22_RS06075 (EQH22_06380)	-	1220460..1221869 (-)	1410	WP_000773464.1	hypothetical protein	-

Sequence

Protein

• Length: 213 a.a.
• Molecular weight: 23534.31 Da
• Isoelectric Point: 9.2465

>NTDB_id=297210 EQH22_RS06045 WP_000151459.1 1216450..1217091(-) (comA) [Streptococcus pneumoniae strain TVO_1901927]
MTIEPGQRIALVGQSGSGKSTLSKIPSGLYKIDTGKVLFDGVNINQIDKKILSQNLGVVPQDSFLLNRSILDNITLKHEV
TSQKIEEVCKAVQIYDEIMAMPMKFNTIISEMGSNISGGQRQRIALARALINNPSIVILDEATSALDTINEERITKYIQS
QGCTQIIIAHRLSTIKDADIIFVMKGGKIVESGNHKYLMTLGGEYYSLYTKRK

Nucleotide

• Length: 642 bp

>NTDB_id=297210 EQH22_RS06045 WP_000151459.1 1216450..1217091(-) (comA) [Streptococcus pneumoniae strain TVO_1901927]
TTGACTATTGAGCCAGGACAGAGAATTGCACTAGTCGGTCAATCGGGGTCAGGAAAAAGTACGTTATCAAAAATACCATC
AGGATTATATAAGATTGATACAGGAAAAGTTTTATTTGATGGTGTAAATATTAATCAAATAGATAAAAAAATATTAAGTC
AAAATTTAGGAGTAGTTCCACAGGATTCGTTTTTATTGAACAGAAGTATTCTTGATAATATAACTTTAAAGCACGAAGTT
ACTTCACAAAAGATAGAGGAAGTTTGTAAAGCAGTTCAAATCTATGATGAAATCATGGCTATGCCGATGAAATTTAATAC
TATCATCTCAGAGATGGGGTCAAATATTTCAGGTGGGCAAAGGCAACGGATAGCACTGGCACGTGCATTAATAAATAATC
CTAGTATTGTAATTTTAGATGAAGCAACTAGTGCATTAGACACTATTAATGAGGAAAGAATAACAAAGTATATACAAAGT
CAGGGTTGTACTCAAATAATTATAGCTCATAGATTGTCAACGATTAAGGATGCGGATATTATTTTTGTAATGAAAGGTGG
TAAGATTGTTGAGTCAGGAAATCATAAGTACTTAATGACTCTTGGTGGAGAGTACTACAGCTTATATACAAAAAGGAAAT
GA

Domains

Predicted by InterProScan.

• ABC transporter (ABC_tran) (1-144)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA	Streptococcus mitis NCTC 12261	43.81	98.592	0.432
comA	Streptococcus mitis SK321	43.333	98.592	0.427
comA	Streptococcus gordonii str. Challis substr. CH1	42.453	99.531	0.423
comA/nlmT	Streptococcus mutans UA159	42.453	99.531	0.423
comA	Streptococcus pneumoniae R6	42.381	98.592	0.418
comA	Streptococcus pneumoniae Rx1	42.381	98.592	0.418
comA	Streptococcus pneumoniae D39	42.381	98.592	0.418
comA	Streptococcus pneumoniae TIGR4	41.429	98.592	0.408
rcrQ	Streptococcus mutans UA159	37.089	100	0.371