Detailed information NTG0029672

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: NMCC_RS10730
• Genome accession: NC_010120
• Coordinates: 2075239..2076426 (-)
• Length: 395 a.a.
• NCBI ID: WP_012222140.1
• Uniprot ID: -
• Organism: Neisseria meningitidis 053442
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 2070239..2081426

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NMCC_RS10705 (NMCC_2027)	-	2070539..2070856 (-)	318	WP_017629223.1	helix-turn-helix domain-containing protein	-
NMCC_RS10710 (NMCC_2028)	-	2071035..2071586 (+)	552	WP_002230190.1	hypothetical protein	-
NMCC_RS10715 (NMCC_2029)	-	2071606..2072301 (+)	696	WP_002233407.1	hypothetical protein	-
NMCC_RS10720 (NMCC_2030)	topA	2072374..2074680 (-)	2307	WP_002220143.1	type I DNA topoisomerase	-
NMCC_RS10725 (NMCC_2031)	-	2074752..2075213 (-)	462	WP_002215351.1	DUF494 domain-containing protein	-
NMCC_RS10730 (NMCC_2032)	dprA	2075239..2076426 (-)	1188	WP_012222140.1	DNA-processing protein DprA	Machinery gene
NMCC_RS10735 (NMCC_2033)	-	2076517..2077794 (-)	1278	WP_002249909.1	sigma-54-dependent transcriptional regulator	-
NMCC_RS10740 (NMCC_2034)	-	2077787..2079907 (-)	2121	WP_012222142.1	sensor histidine kinase	-
NMCC_RS10745 (NMCC_2035)	-	2079907..2080506 (-)	600	WP_012222143.1	DUF4390 domain-containing protein	-

Sequence

Protein

• Length: 395 a.a.
• Molecular weight: 42111.24 Da
• Isoelectric Point: 6.1085

>NTDB_id=29672 NMCC_RS10730 WP_012222140.1 2075239..2076426(-) (dprA) [Neisseria meningitidis 053442]
MTEDERFAWLQLAFTPYIGAESFLLLMRRFGSAQNALSAPAEQVAALIRHKQALEAWRNAEKRALARQAAEAALEWEMRD
GCRLMLLQDEDFPEMLTQGLTAPPVLFLRGNVRLLHKPSAAIVGSRHATPQAMRIAKDFGKSLGGQNIPVVSGMASGIDT
AAHQGALEAEGGTIAVWGTGIDRIYPPSNKNLAYEIAEKGLIVSEFPIGTRPYAGNFPRRNRLIAALSQVTLVVEAALES
GSLITAGLAAEMGREVMAVPGSIDSPHSKGCHKLIKDGAKLVECLDDILNECPGLLQNTGASSYSINKDTPDTGRRAVQT
AYAPPPAAKMPSEAAAGGTAHGGILDKMGFDPVHPDVLAEQLAMPAADLYAALLELELDGSVAAMPGGRYQRIRT

Nucleotide

• Length: 1188 bp

>NTDB_id=29672 NMCC_RS10730 WP_012222140.1 2075239..2076426(-) (dprA) [Neisseria meningitidis 053442]
ATGACAGAGGACGAACGTTTCGCGTGGCTGCAATTGGCGTTTACGCCCTATATCGGCGCGGAAAGTTTCCTGCTGCTGAT
GCGCCGTTTCGGCAGCGCGCAAAATGCCCTGTCCGCACCGGCGGAACAGGTGGCGGCACTGATACGGCACAAACAGGCGC
TTGAGGCTTGGCGCAATGCGGAAAAACGCGCTCTGGCGCGGCAGGCGGCAGAAGCGGCATTGGAATGGGAAATGCGGGAC
GGATGCCGTCTGATGCTGCTTCAGGATGAAGATTTTCCCGAAATGCTGACGCAGGGGCTGACCGCGCCGCCGGTTTTGTT
TTTGCGCGGCAACGTGCGGCTGCTGCACAAGCCTTCCGCCGCCATCGTCGGCAGCCGCCATGCCACGCCGCAGGCGATGC
GGATTGCCAAAGATTTCGGCAAGTCGTTGGGCGGGCAAAATATCCCCGTTGTGTCGGGTATGGCTTCCGGTATCGATACT
GCCGCCCATCAGGGCGCACTGGAGGCAGAAGGCGGCACCATCGCCGTGTGGGGGACGGGTATAGACCGCATTTACCCGCC
GTCCAATAAAAACCTTGCCTATGAAATCGCCGAAAAAGGATTGATTGTCAGCGAGTTTCCCATCGGTACGCGCCCGTATG
CCGGCAACTTTCCGCGCCGCAACCGCCTGATTGCCGCGCTGTCGCAGGTTACGCTGGTGGTTGAAGCTGCGTTGGAATCC
GGTTCGCTGATTACCGCCGGCTTGGCGGCAGAAATGGGGCGCGAAGTGATGGCAGTACCCGGTTCGATAGACAGTCCACA
CAGCAAAGGCTGCCACAAACTGATTAAAGACGGCGCGAAATTGGTGGAATGCCTGGACGACATCCTGAACGAATGCCCGG
GGCTATTGCAAAATACGGGTGCTTCATCATATTCTATAAATAAGGATACGCCCGACACGGGACGCCGCGCCGTTCAGACG
GCATACGCCCCGCCGCCTGCCGCAAAAATGCCGTCTGAAGCGGCGGCAGGCGGCACAGCCCACGGCGGCATACTGGATAA
AATGGGTTTCGACCCCGTCCATCCCGACGTGCTTGCCGAGCAGCTTGCTATGCCTGCCGCAGATTTGTATGCCGCACTGT
TGGAATTGGAATTGGACGGCAGCGTTGCCGCAATGCCCGGCGGCAGATACCAGCGTATCCGAACTTGA

Domains

Predicted by InterproScan.

• DprA winged helix domain (DprA_WH) (332-388)

• DNA recombination-mediator protein A (DNA_processg_A) (79-283)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Neisseria gonorrhoeae strain FA1090	95.696	100	0.957
dprA	Neisseria gonorrhoeae MS11	95.443	100	0.954
dprA	Neisseria meningitidis strain C311	91.688	100	0.922
dprA	Neisseria meningitidis MC58	91.688	100	0.922
dprA	Vibrio cholerae strain A1552	37.531	100	0.377