Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGD   Type   Machinery gene
Locus tag   SUB_RS00745 Genome accession   NC_012004
Coordinates   125057..125494 (+) Length   145 a.a.
NCBI ID   WP_012657676.1    Uniprot ID   B9DT01
Organism   Streptococcus uberis 0140J     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 120057..130494
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SUB_RS00725 (SUB0117) - 122433..122798 (+) 366 WP_041817508.1 DUF1033 family protein -
  SUB_RS00730 (SUB0118) comGA/cglA 122871..123812 (+) 942 WP_012657673.1 competence type IV pilus ATPase ComGA Machinery gene
  SUB_RS00735 (SUB0119) comGB 123724..124779 (+) 1056 WP_172631729.1 competence type IV pilus assembly protein ComGB Machinery gene
  SUB_RS00740 (SUB0120) comGC/cglC 124780..125103 (+) 324 WP_012657675.1 competence type IV pilus major pilin ComGC Machinery gene
  SUB_RS00745 (SUB0121) comGD 125057..125494 (+) 438 WP_012657676.1 competence type IV pilus minor pilin ComGD Machinery gene
  SUB_RS00750 (SUB0122) comGE 125466..125765 (+) 300 WP_012657677.1 competence type IV pilus minor pilin ComGE Machinery gene
  SUB_RS00755 (SUB0123) comGF 125725..126180 (+) 456 WP_012657678.1 competence type IV pilus minor pilin ComGF Machinery gene
  SUB_RS00760 (SUB0124) comGG 126158..126517 (+) 360 WP_012657679.1 competence type IV pilus minor pilin ComGG -
  SUB_RS00765 (SUB0125) comGH 126562..127518 (+) 957 WP_012657680.1 class I SAM-dependent methyltransferase Machinery gene
  SUB_RS00770 (SUB0126) - 127574..128764 (+) 1191 WP_012657681.1 acetate kinase -
  SUB_RS00775 (SUB0127) - 128882..129085 (+) 204 WP_012657682.1 helix-turn-helix transcriptional regulator -
  SUB_RS00780 (SUB0128) - 129087..129539 (+) 453 WP_012657683.1 hypothetical protein -
  SUB_RS00785 (SUB0129) - 129548..130201 (+) 654 WP_012657684.1 CPBP family intramembrane glutamic endopeptidase -

Sequence

Protein


Download         Length: 145 a.a.        Molecular weight: 16695.42 Da        Isoelectric Point: 9.7168

>NTDB_id=29636 SUB_RS00745 WP_012657676.1 125057..125494(+) (comGD) [Streptococcus uberis 0140J]
MTIIKNILVKISCCHSKAFTLAESLLCLAVTTFTILLLSSSLAGVYESVERELFFISFEHFYRHCQKMSVLKQEESALHF
TAHRIKYGQRELVIPDHIRLLNQGTIPFNKTGGSHSLAKIEWQTPREKLTYQLNLGSGNYQKRRH

Nucleotide


Download         Length: 438 bp        

>NTDB_id=29636 SUB_RS00745 WP_012657676.1 125057..125494(+) (comGD) [Streptococcus uberis 0140J]
ATGACTATTATCAAAAACATCCTGGTGAAAATAAGCTGTTGCCATAGTAAAGCCTTCACCCTTGCGGAGAGTCTCCTGTG
TCTGGCAGTGACGACCTTCACCATTCTGTTGCTAAGTAGCTCTCTGGCGGGTGTTTATGAAAGTGTGGAAAGAGAATTGT
TTTTCATTTCCTTTGAACATTTTTATCGTCATTGTCAAAAAATGAGTGTTTTAAAACAAGAAGAAAGTGCTTTGCACTTT
ACAGCACATCGTATCAAATATGGTCAGCGTGAATTAGTGATTCCAGATCATATTCGATTGTTAAATCAAGGGACTATCCC
TTTTAACAAAACAGGTGGTAGTCATTCCTTAGCAAAAATTGAGTGGCAAACACCAAGGGAGAAATTGACATACCAGCTAA
ATCTAGGGAGTGGAAATTATCAAAAACGAAGACATTAA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB B9DT01

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGD Streptococcus mutans UA140

45.669

87.586

0.4
  comGD Streptococcus mutans UA159

45.669

87.586

0.4
  comGD Streptococcus gordonii str. Challis substr. CH1

39.259

93.103

0.366

Multiple sequence alignment