Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   NMCC_RS01935 Genome accession   NC_010120
Coordinates   376816..379929 (-) Length   1037 a.a.
NCBI ID   WP_079884946.1    Uniprot ID   -
Organism   Neisseria meningitidis 053442     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 371816..384929
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NMCC_RS15280 - 371854..372205 (+) 352 Protein_345 hypothetical protein -
  NMCC_RS01910 (NMCC_0370) - 372451..372840 (-) 390 WP_002240760.1 endonuclease domain-containing protein -
  NMCC_RS01920 (NMCC_0372) - 373420..373557 (-) 138 WP_002214606.1 VOC family protein -
  NMCC_RS01925 (NMCC_0373) carA 373603..374736 (-) 1134 WP_002217954.1 glutamine-hydrolyzing carbamoyl-phosphate synthase small subunit -
  NMCC_RS01935 (NMCC_0375) pilC 376816..379929 (-) 3114 WP_079884946.1 PilC family type IV pilus tip adhesin Machinery gene
  NMCC_RS01940 (NMCC_0376) apbC 380883..381962 (-) 1080 WP_002243010.1 iron-sulfur cluster carrier protein ApbC -
  NMCC_RS01950 (NMCC_0378) - 382327..382836 (+) 510 WP_002221509.1 protein disulfide oxidoreductase -
  NMCC_RS01960 (NMCC_0379) nadR 383179..383619 (+) 441 WP_002221507.1 MarR family adhesin repressor NadR -
  NMCC_RS01965 (NMCC_0380) hpaC 383734..384234 (+) 501 WP_002224077.1 4-hydroxyphenylacetate 3-monooxygenase, reductase component -

Sequence

Protein


Download         Length: 1037 a.a.        Molecular weight: 114118.94 Da        Isoelectric Point: 9.6552

>NTDB_id=29636 NMCC_RS01935 WP_079884946.1 376816..379929(-) (pilC) [Neisseria meningitidis 053442]
MNKTLKRRVFRHTALYAAILMFSHTGGGGGAMAQTYNYAIVMNERNQLDVRRDGQYQKSTLKDKDRERKFIYTSQRNNLG
QQNNFISFDNTDTLVSQQRGTAVFGTATYLPPYGKVSGFDADGLEKRNNAVDWIRTTRIALAGYRYDNVVCRSTTDCPKL
VYKTRFSFDNPDLAKTGVGLDKHTEPSRDNSPIYKLKDHPWLGVSFNLGAEGTAKNGKTINKLVSSFNEKNSNNNLVYTT
EGRDISLGDWQRETTAMAYYLNAKLHLLDKKGIKDIAQGKTVDLGTLRPRVETTGRSWLNFWAKWDIKDNGQIPVKLGLP
EVKAGRCINKANPNPKAQALSPALTAPALWFGAGQDGKAEMYSASVSTYPDSSSSRIFLQNLKRKTDTSRPGRYSLADLS
ASDIQSKEPTFTSRQTIIRLDGGVREIKLDRSNEATGLNGNDGKNETFGIVSEGSFMPDDSEWKKVLLPWTVRGSADDGR
FKSINQESSKYSQRYRIRENGNNSKRDLGDIVNSPIVAVGEYLATSANDGMVHIFKQSGGDKRSYNLKLSYIPGTMPRKD
IENKDSTLAKELRAFAEKGYVGDRYGVDGGFVLRRITDDQDKQKHFFMFGAMGLGGRGAYALDLTKAENGDPTAVSLFDV
KHDNNGKNSNNSVQLGYTVGTPQIGKTHDGKYAAFLASGYATKQIDSGENTTALYVYDLENNNGTLIRKIEVTSGKGGLS
SPTLVDKDLDGIVDIAYAGDRGGNMYRFDLSGQDPNQWSVRTIFSGNKPITSAPAISQLKDKRVVIFGTGSDLSEEDVDS
KEIQHVYGIFDNDTDTGTAQDGQGKGLLEQKLEKDKDGKTLFLSDYKRSDGSGDKGWVVKLEAGQRVTVKPTVVLRTAFV
TIHKYTGNDKCGAETAILGINTADGGKLTKKSARPIVPADNTAVAQYSGHKKTSSGKSIPIGCMEKDNGIVCPNGYVYDK
PVNVRYLDEKKTDGFSTTADGDAGGSGTFKEGKKPARNNRCFSRKGVRTLLMNDLDSLDITGPMCGMKRISWREVFY

Nucleotide


Download         Length: 3114 bp        

>NTDB_id=29636 NMCC_RS01935 WP_079884946.1 376816..379929(-) (pilC) [Neisseria meningitidis 053442]
ATGAATAAAACTTTAAAAAGGCGGGTTTTCCGCCATACCGCGCTTTATGCCGCCATCTTGATGTTTTCCCATACCGGCGG
GGGGGGGGGGGCGATGGCGCAAACCTATAACTACGCTATTGTCATGAACGAACGAAATCAGCTGGATGTAAGGAGGGATG
GGCAATATCAAAAATCAACATTAAAGGACAAAGACAGGGAACGCAAATTTATCTATACGAGCCAGAGAAACAATTTGGGC
CAACAAAACAATTTTATCTCATTCGACAATACCGATACCCTTGTTTCTCAACAAAGAGGTACTGCCGTTTTTGGCACAGC
CACCTACCTGCCGCCCTACGGCAAGGTTTCCGGTTTTGATGCCGACGGGCTGGAAAAGCGCAACAATGCCGTCGATTGGA
TTCGTACCACCCGCATCGCGCTGGCAGGCTACAGATACGACAATGTCGTATGCAGAAGCACCACAGACTGTCCCAAACTT
GTCTATAAAACCCGATTTTCCTTCGATAATCCCGACTTGGCAAAAACAGGAGTCGGGCTGGATAAGCACACAGAGCCAAG
CCGCGACAATTCGCCCATTTACAAATTGAAGGATCATCCATGGTTGGGCGTGTCTTTCAATTTGGGTGCCGAGGGTACCG
CCAAAAATGGTAAGACAATCAACAAATTGGTATCTTCTTTTAATGAAAAGAATAGTAATAACAACCTCGTCTATACCACG
GAAGGCCGCGATATTTCCTTGGGCGACTGGCAGCGCGAAACGACCGCCATGGCCTATTATCTGAACGCCAAACTGCACCT
GCTGGACAAAAAAGGGATTAAAGATATCGCCCAAGGCAAAACAGTGGATTTGGGCACCTTGAGACCGCGCGTCGAGACGA
CAGGACGAAGCTGGCTAAATTTTTGGGCTAAGTGGGACATTAAAGATAACGGGCAGATTCCGGTCAAGCTCGGCCTGCCG
GAAGTCAAAGCAGGCCGCTGCATCAACAAAGCGAACCCCAATCCCAAAGCCCAAGCCCTTTCCCCCGCCTTGACCGCCCC
CGCGCTGTGGTTCGGAGCTGGGCAAGATGGTAAGGCGGAGATGTATTCCGCTTCGGTTTCCACCTACCCCGACAGTTCGA
GCAGCCGCATCTTCCTTCAAAATCTGAAAAGAAAAACCGACACCAGCAGACCCGGCCGCTATTCCCTCGCAGACTTGAGT
GCGTCGGATATTCAAAGTAAAGAGCCGACTTTCACAAGTCGGCAAACAATCATCCGATTGGATGGCGGCGTACGTGAGAT
CAAACTGGATAGAAGCAATGAGGCCACCGGTTTAAATGGAAATGACGGCAAAAACGAAACTTTCGGCATTGTTAGCGAAG
GGAGCTTCATGCCTGATGACAGCGAGTGGAAAAAAGTGCTGCTGCCTTGGACGGTTCGGGGTTCTGCTGATGACGGTCGA
TTTAAATCAATTAACCAAGAATCAAGCAAATACAGCCAAAGATACCGCATCCGCGAAAACGGCAACAATAGCAAGCGTGA
TTTGGGCGACATCGTCAACAGCCCCATCGTGGCGGTCGGCGAATATCTAGCTACTTCCGCCAACGACGGGATGGTGCATA
TCTTCAAACAAAGCGGCGGGGACAAGCGCAGCTACAATCTGAAGCTCAGCTACATCCCCGGAACGATGCCGCGCAAGGAT
ATTGAAAACAAAGATTCCACCCTTGCCAAAGAGCTGCGCGCCTTTGCCGAAAAAGGCTATGTGGGCGACCGCTACGGCGT
GGACGGCGGCTTTGTCTTGCGCCGCATTACAGATGACCAAGACAAGCAAAAACATTTCTTTATGTTTGGTGCGATGGGCC
TGGGCGGCAGAGGCGCGTATGCCTTGGATTTGACCAAAGCCGAAAACGGTGACCCGACCGCCGTTTCCCTGTTTGATGTC
AAACATGACAATAATGGCAAGAATAGCAATAATAGCGTGCAATTAGGCTACACCGTCGGCACGCCGCAAATCGGCAAAAC
CCACGACGGCAAATACGCCGCTTTCCTCGCCTCCGGTTATGCGACTAAACAAATTGACAGCGGCGAGAATACAACCGCGC
TGTATGTGTATGATTTGGAAAACAACAATGGTACGCTGATTAGAAAAATCGAAGTAACCAGCGGCAAGGGCGGGCTTTCG
TCCCCCACGCTGGTGGATAAAGATTTGGACGGCATTGTCGATATCGCCTATGCCGGCGATCGCGGCGGGAATATGTACCG
CTTTGATTTGAGCGGTCAAGATCCTAATCAATGGTCTGTACGCACCATTTTCAGCGGCAACAAACCGATTACTTCCGCGC
CCGCCATTTCCCAACTGAAAGACAAACGCGTGGTTATCTTCGGCACGGGCAGCGATTTGAGTGAAGAGGATGTGGACAGC
AAAGAAATCCAACACGTTTACGGTATTTTTGACAATGACACAGACACGGGTACGGCGCAAGACGGGCAGGGCAAAGGGCT
GCTCGAGCAAAAGCTGGAAAAAGACAAAGACGGCAAAACGCTGTTTTTAAGCGACTACAAAAGGTCTGACGGCTCGGGCG
ACAAGGGCTGGGTAGTGAAATTGGAAGCCGGACAGCGCGTTACCGTCAAACCGACCGTGGTATTGCGTACCGCCTTTGTA
ACCATCCATAAATATACGGGTAATGACAAATGCGGCGCGGAAACCGCCATTTTGGGCATCAATACCGCCGACGGCGGCAA
GCTGACCAAGAAAAGCGCGCGCCCGATTGTGCCGGCCGACAATACGGCTGTCGCGCAATATTCCGGCCATAAGAAAACTT
CCAGCGGCAAATCCATCCCTATAGGTTGTATGGAAAAAGACAATGGAATCGTCTGCCCGAACGGATATGTTTACGACAAA
CCGGTTAATGTGCGTTATCTGGATGAAAAGAAAACAGACGGATTTTCAACAACGGCAGACGGCGATGCGGGCGGCAGCGG
AACATTCAAAGAGGGTAAAAAACCCGCCCGCAATAACCGGTGCTTCTCCAGAAAAGGTGTGCGCACCCTGCTGATGAACG
ATTTGGACAGCTTGGACATTACCGGCCCGATGTGCGGTATGAAACGAATCAGCTGGCGTGAAGTCTTCTACTGA

Domains

Predicted by InterproScan.

Neisseria PilC beta-propeller domain (T4P_PilY1)

(508-844)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Neisseria meningitidis A1493

77.979

100

0.789

Multiple sequence alignment