Detailed information NTG0294301

Bioinformatically predicted

Overview

• Name: comA
• Type: Regulator
• Locus tag: DL317_RS05980
• Genome accession: NZ_CP029615
• Coordinates: 1280348..1282498 (-)
• Length: 716 a.a.
• NCBI ID: WP_113897044.1
• Uniprot ID: A0A347T8P7
• Organism: Limosilactobacillus reuteri strain SKKU-OGDONS-01
• Function: processing and transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 1275348..1287498

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DL317_RS05955 (DL317_05955)	-	1276446..1276667 (-)	222	WP_003670244.1	hypothetical protein	-
DL317_RS05960 (DL317_05960)	-	1277172..1278359 (+)	1188	WP_113897041.1	aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme	-
DL317_RS05965 (DL317_05965)	-	1278361..1279356 (+)	996	WP_113897593.1	D-2-hydroxyacid dehydrogenase	-
DL317_RS05970 (DL317_05970)	-	1279424..1279852 (+)	429	WP_113897042.1	OsmC family protein	-
DL317_RS05980 (DL317_05980)	comA	1280348..1282498 (-)	2151	WP_113897044.1	peptide cleavage/export ABC transporter	Regulator
DL317_RS05985 (DL317_05985)	-	1282681..1283649 (+)	969	WP_113897045.1	IS30 family transposase	-
DL317_RS10880	-	1283853..1284014 (-)	162	WP_162859766.1	hypothetical protein	-
DL317_RS10885	-	1284056..1284214 (-)	159	WP_162859767.1	hypothetical protein	-
DL317_RS05990 (DL317_05990)	-	1284610..1285377 (-)	768	WP_113897046.1	LytR/AlgR family response regulator transcription factor	-
DL317_RS05995 (DL317_05995)	-	1285385..1286419 (-)	1035	WP_231122391.1	GHKL domain-containing protein	-
DL317_RS11270	-	1286695..1286826 (-)	132	WP_257496822.1	hypothetical protein	-
DL317_RS10890	-	1286853..1287017 (-)	165	WP_162859768.1	hypothetical protein	-

Sequence

Protein

• Length: 716 a.a.
• Molecular weight: 81154.30 Da
• Isoelectric Point: 7.3139

>NTDB_id=294301 DL317_RS05980 WP_113897044.1 1280348..1282498(-) (comA) [Limosilactobacillus reuteri strain SKKU-OGDONS-01]
MKINYPHYVAQVDEADCGVASLAMILRNFGSVYPIAKLRDLARTTKQGTTALGLVKAAKHLGLDVIPIQADISLFDDPEI
TYPLIAHVIKDDLLHYCVVFKADQDYIYVADPDPATKVQKMTRDEFDRLWSGVFLLFSPAKGYTPQKEPLAGLTTMFQQL
ANYKKDISGIVIAAMLITFISIVGSYYLQLIIDRFIPSKNINGLAILAGSLLVVYVFNSLFNYLRDVLLTRLDQKLTSQI
SLRYIHHVYRLPMRFFSTRKTGEITSRFNDINKIIDALSSTIISMFLDVGVMVIIGIVLSLYDRSLFLTTISTIPIYVII
IYAFNKRFVKLDQEQMESNAQLSSAIIEDLKGVETLKVLQLENIRYKNVEKQFADFLRKNLTYVKTKSFQDAIKMWIQYG
LVTIILFQGAILVIQDRLSIGTLMAFNALLAFFVSPLQNIINLQPKLQEAKVANNRLNEVLQVDTEKSDTNSQDQTDLIG
PINIQHVDYSYEYSRPILQDINLQIGCNDKLAIVGLSGSGKSTLAKLLVGFYLPTQGQIEFNQHKTTEINLCDIRQYVHY
LPQSPQLFSGTIKDNLLMGLDREVSAEEIDNACKLALIYNDIQEMPLKYETKLDEEATALSGGQKQRLTIARALLTSARV
LIFDESTSSLDPITEKRIVENLLSIKDRTMIFIAHRLSIAKKVNRVVVMRDGKIIEQGTHQELLNHHQEYYNLWNA

Nucleotide

• Length: 2151 bp

>NTDB_id=294301 DL317_RS05980 WP_113897044.1 1280348..1282498(-) (comA) [Limosilactobacillus reuteri strain SKKU-OGDONS-01]
ATGAAAATCAATTATCCTCATTATGTAGCCCAAGTTGATGAAGCAGATTGTGGGGTTGCCTCTTTAGCGATGATTTTGCG
CAATTTTGGGTCTGTTTATCCAATCGCAAAATTACGTGACTTAGCACGGACGACTAAGCAAGGAACTACCGCTTTAGGAC
TTGTAAAAGCAGCAAAGCATCTTGGATTAGATGTTATTCCCATTCAAGCAGATATATCATTGTTTGATGATCCTGAAATT
ACTTACCCGTTGATCGCGCATGTGATTAAGGATGATTTACTTCATTACTGTGTCGTTTTTAAGGCTGATCAAGATTACAT
CTATGTAGCTGATCCAGATCCTGCTACGAAAGTACAAAAAATGACTCGGGATGAATTTGATCGTTTATGGTCAGGTGTAT
TTTTGCTTTTTTCGCCTGCTAAGGGGTATACACCGCAAAAAGAACCTTTAGCTGGATTAACGACGATGTTTCAACAATTA
GCTAATTATAAAAAAGATATATCTGGAATTGTTATTGCGGCAATGCTAATTACTTTCATCAGCATCGTCGGTTCATACTA
TCTCCAATTAATTATTGATCGGTTTATTCCCTCGAAAAATATTAATGGCTTAGCGATCCTCGCTGGTAGTTTATTAGTAG
TTTATGTGTTTAATTCTCTTTTTAATTATCTGCGAGATGTTCTTTTGACTAGGCTGGATCAAAAACTGACATCACAAATA
AGTCTTAGATATATTCACCATGTTTATCGTCTACCGATGCGATTTTTCTCCACAAGAAAAACGGGAGAAATTACTTCACG
GTTTAATGACATTAATAAGATTATTGATGCCTTATCAAGCACTATTATTTCAATGTTCTTAGACGTTGGCGTGATGGTGA
TTATAGGAATTGTTCTTTCTTTATATGATCGGTCATTATTTTTAACTACAATTAGTACCATTCCGATTTATGTCATTATT
ATTTATGCCTTTAATAAGCGCTTTGTTAAACTTGATCAGGAACAGATGGAGAGTAATGCTCAATTAAGTTCTGCAATTAT
TGAGGATTTAAAAGGCGTAGAGACATTGAAAGTGCTGCAACTTGAAAATATCCGTTATAAAAATGTTGAAAAGCAATTTG
CGGATTTTTTACGAAAGAATCTAACATATGTTAAAACTAAATCTTTTCAGGATGCAATTAAAATGTGGATTCAATACGGT
TTAGTAACAATCATTCTTTTTCAAGGAGCAATTTTGGTAATTCAAGACCGATTAAGTATTGGGACATTAATGGCCTTTAA
TGCATTATTAGCCTTTTTTGTCAGTCCGTTGCAAAATATTATTAATCTTCAACCTAAACTCCAAGAAGCTAAAGTAGCGA
ATAATCGATTGAATGAAGTGCTGCAAGTTGATACCGAAAAGTCAGATACGAATTCTCAGGATCAAACAGATTTAATAGGT
CCGATAAACATTCAACATGTTGACTATTCATATGAATATAGTCGTCCAATTTTACAAGATATCAATCTTCAAATTGGTTG
TAATGACAAATTGGCAATTGTAGGGTTGAGCGGTTCTGGTAAATCGACCTTGGCAAAGTTGTTAGTTGGCTTTTATTTAC
CTACTCAAGGGCAGATAGAATTTAATCAGCATAAAACAACAGAGATTAATCTTTGCGATATTAGACAATATGTACATTAC
TTACCCCAATCGCCACAATTATTTTCGGGAACAATCAAAGATAATTTGCTAATGGGATTAGACCGTGAAGTATCTGCTGA
AGAAATCGATAATGCATGTAAATTGGCATTAATCTATAATGATATTCAAGAGATGCCCTTAAAATATGAAACAAAACTAG
ATGAAGAAGCAACCGCATTATCTGGTGGTCAAAAACAACGCTTGACGATTGCACGAGCACTCCTAACTTCTGCGCGTGTT
TTAATTTTTGATGAATCAACAAGTAGCTTAGATCCAATTACTGAAAAAAGAATCGTTGAAAATTTGCTTAGTATTAAAGA
CCGCACAATGATTTTTATTGCCCACCGCCTTTCAATTGCTAAAAAGGTCAATAGAGTGGTAGTAATGCGCGACGGAAAAA
TCATTGAGCAGGGTACTCACCAGGAACTTTTGAATCATCATCAAGAATACTATAATTTGTGGAATGCATAA

Domains

Predicted by InterproScan.

• ABC transporter (ABC_tran) (498-648)

• Peptidase C39 family (Peptidase_C39) (7-141)

• ABC transporter transmembrane region (ABC_membrane) (170-437)

3D structure

• AlphaFold DB: A0A347T8P7

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA	Streptococcus mitis NCTC 12261	48.607	100	0.487
comA	Streptococcus pneumoniae Rx1	48.468	100	0.486
comA	Streptococcus pneumoniae D39	48.468	100	0.486
comA	Streptococcus pneumoniae R6	48.468	100	0.486
comA	Streptococcus pneumoniae TIGR4	48.468	100	0.486
comA	Streptococcus mitis SK321	48.189	100	0.483
comA	Streptococcus gordonii str. Challis substr. CH1	46.518	100	0.466
comA/nlmT	Streptococcus mutans UA159	46.564	99.581	0.464