Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Regulator
Locus tag   C0J54_RS01650 Genome accession   NZ_CP029613
Coordinates   328446..330596 (+) Length   716 a.a.
NCBI ID   WP_113897044.1    Uniprot ID   A0A347T8P7
Organism   Limosilactobacillus reuteri strain Byun-re-01     
Function   processing and transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 323446..335596
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  C0J54_RS10940 - 323927..324091 (+) 165 WP_162859768.1 hypothetical protein -
  C0J54_RS11250 - 324118..324249 (+) 132 WP_257496822.1 hypothetical protein -
  C0J54_RS01635 - 324507..325559 (+) 1053 WP_225433912.1 GHKL domain-containing protein -
  C0J54_RS01640 - 325567..326334 (+) 768 WP_113897046.1 LytR/AlgR family response regulator transcription factor -
  C0J54_RS10945 - 326730..326888 (+) 159 WP_162859767.1 hypothetical protein -
  C0J54_RS10950 - 326930..327091 (+) 162 WP_162859766.1 hypothetical protein -
  C0J54_RS01645 - 327295..328263 (-) 969 WP_113897045.1 IS30 family transposase -
  C0J54_RS01650 comA 328446..330596 (+) 2151 WP_113897044.1 peptide cleavage/export ABC transporter Regulator
  C0J54_RS01655 - 330629..330814 (-) 186 WP_113897043.1 hypothetical protein -
  C0J54_RS01660 - 331092..331520 (-) 429 WP_113897042.1 OsmC family protein -
  C0J54_RS01665 - 331588..332583 (-) 996 WP_113898144.1 NAD(P)-dependent oxidoreductase -
  C0J54_RS01670 - 332585..333772 (-) 1188 WP_113897041.1 aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme -
  C0J54_RS01675 - 334277..334498 (+) 222 WP_003670244.1 hypothetical protein -

Sequence

Protein


Download         Length: 716 a.a.        Molecular weight: 81154.30 Da        Isoelectric Point: 7.3139

>NTDB_id=294256 C0J54_RS01650 WP_113897044.1 328446..330596(+) (comA) [Limosilactobacillus reuteri strain Byun-re-01]
MKINYPHYVAQVDEADCGVASLAMILRNFGSVYPIAKLRDLARTTKQGTTALGLVKAAKHLGLDVIPIQADISLFDDPEI
TYPLIAHVIKDDLLHYCVVFKADQDYIYVADPDPATKVQKMTRDEFDRLWSGVFLLFSPAKGYTPQKEPLAGLTTMFQQL
ANYKKDISGIVIAAMLITFISIVGSYYLQLIIDRFIPSKNINGLAILAGSLLVVYVFNSLFNYLRDVLLTRLDQKLTSQI
SLRYIHHVYRLPMRFFSTRKTGEITSRFNDINKIIDALSSTIISMFLDVGVMVIIGIVLSLYDRSLFLTTISTIPIYVII
IYAFNKRFVKLDQEQMESNAQLSSAIIEDLKGVETLKVLQLENIRYKNVEKQFADFLRKNLTYVKTKSFQDAIKMWIQYG
LVTIILFQGAILVIQDRLSIGTLMAFNALLAFFVSPLQNIINLQPKLQEAKVANNRLNEVLQVDTEKSDTNSQDQTDLIG
PINIQHVDYSYEYSRPILQDINLQIGCNDKLAIVGLSGSGKSTLAKLLVGFYLPTQGQIEFNQHKTTEINLCDIRQYVHY
LPQSPQLFSGTIKDNLLMGLDREVSAEEIDNACKLALIYNDIQEMPLKYETKLDEEATALSGGQKQRLTIARALLTSARV
LIFDESTSSLDPITEKRIVENLLSIKDRTMIFIAHRLSIAKKVNRVVVMRDGKIIEQGTHQELLNHHQEYYNLWNA

Nucleotide


Download         Length: 2151 bp        

>NTDB_id=294256 C0J54_RS01650 WP_113897044.1 328446..330596(+) (comA) [Limosilactobacillus reuteri strain Byun-re-01]
ATGAAAATCAATTATCCTCATTATGTAGCCCAAGTTGATGAAGCAGATTGTGGGGTTGCCTCTTTAGCGATGATTTTGCG
CAATTTTGGGTCTGTTTATCCAATCGCAAAATTACGTGACTTAGCACGGACGACTAAGCAAGGAACTACCGCTTTAGGAC
TTGTAAAAGCAGCAAAGCATCTTGGATTAGATGTTATTCCCATTCAAGCAGATATATCATTGTTTGATGATCCTGAAATT
ACTTACCCGTTGATCGCGCATGTGATTAAGGATGATTTACTTCATTACTGTGTCGTTTTTAAGGCTGATCAAGATTACAT
CTATGTAGCTGATCCAGATCCTGCTACGAAAGTACAAAAAATGACTCGGGATGAATTTGATCGTTTATGGTCAGGTGTAT
TTTTGCTTTTTTCGCCTGCTAAGGGGTATACACCGCAAAAAGAACCTTTAGCTGGATTAACGACGATGTTTCAACAATTA
GCTAATTATAAAAAAGATATATCTGGAATTGTTATTGCGGCAATGCTAATTACTTTCATCAGCATCGTCGGTTCATACTA
TCTCCAATTAATTATTGATCGGTTTATTCCCTCGAAAAATATTAATGGCTTAGCGATCCTCGCTGGTAGTTTATTAGTAG
TTTATGTGTTTAATTCTCTTTTTAATTATCTGCGAGATGTTCTTTTGACTAGGCTGGATCAAAAACTGACATCACAAATA
AGTCTTAGATATATTCACCATGTTTATCGTCTACCGATGCGATTTTTCTCCACAAGAAAAACGGGAGAAATTACTTCACG
GTTTAATGACATTAATAAGATTATTGATGCCTTATCAAGCACTATTATTTCAATGTTCTTAGACGTTGGCGTGATGGTGA
TTATAGGAATTGTTCTTTCTTTATATGATCGGTCATTATTTTTAACTACAATTAGTACCATTCCGATTTATGTCATTATT
ATTTATGCCTTTAATAAGCGCTTTGTTAAACTTGATCAGGAACAGATGGAGAGTAATGCTCAATTAAGTTCTGCAATTAT
TGAGGATTTAAAAGGCGTAGAGACATTGAAAGTGCTGCAACTTGAAAATATCCGTTATAAAAATGTTGAAAAGCAATTTG
CGGATTTTTTACGAAAGAATCTAACATATGTTAAAACTAAATCTTTTCAGGATGCAATTAAAATGTGGATTCAATACGGT
TTAGTAACAATCATTCTTTTTCAAGGAGCAATTTTGGTAATTCAAGACCGATTAAGTATTGGGACATTAATGGCCTTTAA
TGCATTATTAGCCTTTTTTGTCAGTCCGTTGCAAAATATTATTAATCTTCAACCTAAACTCCAAGAAGCTAAAGTAGCGA
ATAATCGATTGAATGAAGTGCTGCAAGTTGATACCGAAAAGTCAGATACGAATTCTCAGGATCAAACAGATTTAATAGGT
CCGATAAACATTCAACATGTTGACTATTCATATGAATATAGTCGTCCAATTTTACAAGATATCAATCTTCAAATTGGTTG
TAATGACAAATTGGCAATTGTAGGGTTGAGCGGTTCTGGTAAATCGACCTTGGCAAAGTTGTTAGTTGGCTTTTATTTAC
CTACTCAAGGGCAGATAGAATTTAATCAGCATAAAACAACAGAGATTAATCTTTGCGATATTAGACAATATGTACATTAC
TTACCCCAATCGCCACAATTATTTTCGGGAACAATCAAAGATAATTTGCTAATGGGATTAGACCGTGAAGTATCTGCTGA
AGAAATCGATAATGCATGTAAATTGGCATTAATCTATAATGATATTCAAGAGATGCCCTTAAAATATGAAACAAAACTAG
ATGAAGAAGCAACCGCATTATCTGGTGGTCAAAAACAACGCTTGACGATTGCACGAGCACTCCTAACTTCTGCGCGTGTT
TTAATTTTTGATGAATCAACAAGTAGCTTAGATCCAATTACTGAAAAAAGAATCGTTGAAAATTTGCTTAGTATTAAAGA
CCGCACAATGATTTTTATTGCCCACCGCCTTTCAATTGCTAAAAAGGTCAATAGAGTGGTAGTAATGCGCGACGGAAAAA
TCATTGAGCAGGGTACTCACCAGGAACTTTTGAATCATCATCAAGAATACTATAATTTGTGGAATGCATAA

Domains

Predicted by InterproScan.

ABC transporter (ABC_tran)

(498-648)

Peptidase C39 family (Peptidase_C39)

(7-141)

ABC transporter transmembrane region (ABC_membrane)

(170-437)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A347T8P7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Streptococcus mitis NCTC 12261

48.607

100

0.487
  comA Streptococcus pneumoniae Rx1

48.468

100

0.486
  comA Streptococcus pneumoniae D39

48.468

100

0.486
  comA Streptococcus pneumoniae R6

48.468

100

0.486
  comA Streptococcus pneumoniae TIGR4

48.468

100

0.486
  comA Streptococcus mitis SK321

48.189

100

0.483
  comA Streptococcus gordonii str. Challis substr. CH1

46.518

100

0.466
  comA/nlmT Streptococcus mutans UA159

46.564

99.581

0.464

Multiple sequence alignment