Detailed information NTG0293521

Bioinformatically predicted

Overview

• Name: comA/nlmT
• Type: Regulator
• Locus tag: DLJ52_RS04570
• Genome accession: NZ_CP029559
• Coordinates: 953583..955730 (-)
• Length: 715 a.a.
• NCBI ID: WP_021673784.1
• Uniprot ID: U2KIX5
• Organism: Streptococcus sobrinus strain NIDR 6715-15
• Function: transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 948583..960730

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DLJ52_RS04545 (DLJ52_04545)	-	949030..949556 (+)	527	Protein_846	YbaK/EbsC family protein	-
DLJ52_RS04550 (DLJ52_04550)	-	949969..950472 (+)	504	WP_019777342.1	phosphatase PAP2 family protein	-
DLJ52_RS04555 (DLJ52_04555)	-	950587..951330 (+)	744	WP_109982563.1	response regulator transcription factor	-
DLJ52_RS04560 (DLJ52_04560)	-	951333..952679 (+)	1347	WP_002998464.1	GHKL domain-containing protein	-
DLJ52_RS04565 (DLJ52_04565)	-	952797..953570 (-)	774	WP_019770708.1	HlyD family efflux transporter periplasmic adaptor subunit	-
DLJ52_RS04570 (DLJ52_04570)	comA/nlmT	953583..955730 (-)	2148	WP_021673784.1	peptide cleavage/export ABC transporter	Regulator
DLJ52_RS04575 (DLJ52_04575)	-	956044..956238 (+)	195	WP_019771729.1	bacteriocin class II family protein	-
DLJ52_RS04580 (DLJ52_04580)	-	956295..956486 (+)	192	WP_019770705.1	Blp family class II bacteriocin	-
DLJ52_RS04585 (DLJ52_04585)	-	956514..956699 (+)	186	WP_019770704.1	hypothetical protein	-
DLJ52_RS04590 (DLJ52_04590)	-	956949..958105 (-)	1157	Protein_855	IS256 family transposase	-
DLJ52_RS04595 (DLJ52_04595)	-	958406..958549 (+)	144	WP_019768643.1	hypothetical protein	-
DLJ52_RS04600 (DLJ52_04600)	-	958581..958985 (+)	405	WP_109982564.1	hypothetical protein	-
DLJ52_RS04605 (DLJ52_04605)	-	959035..960069 (+)	1035	WP_032672939.1	thioredoxin family protein	-

Sequence

Protein

• Length: 715 a.a.
• Molecular weight: 80357.42 Da
• Isoelectric Point: 8.1599

>NTDB_id=293521 DLJ52_RS04570 WP_021673784.1 953583..955730(-) (comA/nlmT) [Streptococcus sobrinus strain NIDR 6715-15]
MNFYKFVPQIDARDCGVAALASIARHYGANYSLAHLRELAKTDKEGTTALGIVEAAQTMGFETRAVRADMSLFEEEEIPY
PFIAHVNKEGKLQHYYVVYKAKKNHLIIGDPDPSVKVTKMSKERFEQEWDGISIFLAPEPAYKPHKDKKNGLLSFIPIIL
KQKGLIFQISLASLLVTLIDILGSYYLQGILDSYIPNQMTSTLTIVSLGLVITYVIQQIMAFSRDYLLTVLSQRLSIDVI
LAYIRHIFSLPMSFFATRRTGEITSRFSDANSIIDALASTILSIFLDCFILIIIGAVLLLQNANLFLLTLLSIPIYTIII
LAFMKPFEKMNQDVMEANSMVSSAIIEDINGMETIKSLTSEDTRYRNVDNEFVDYLDKSFKRHKYEILQTSLKKGAQLIL
NVAILWFGSTLVMVNKISIGQLVAYNSLLTYFTNPLENIINLQTKLQSAKVANNRLNEVYLVSSEFDQKTTKVNQEAPSG
DIVFSDVSYKYGFGRDTLTDINLKIAKGSKISLVGISGSGKTTLAKLIVNFFQPYKGEITIKSLNTNLLDKRLLRKYINY
LPQQPYVFSGSILENLTLGADESVSQEDIMKACEMAEIRRDIEQMPLGYQTELSDGAGLSGGQKQRIALARALLTKSPIM
VLDEATSGLDVLTEKKVIDNLMKMTEKTIIFVAHRLSISERTDKIVVLDQGRIIETGSHQDLLKKQGFYYQLFNK

Nucleotide

• Length: 2148 bp

>NTDB_id=293521 DLJ52_RS04570 WP_021673784.1 953583..955730(-) (comA/nlmT) [Streptococcus sobrinus strain NIDR 6715-15]
ATGAATTTTTACAAATTTGTTCCTCAGATTGATGCCAGAGACTGTGGAGTTGCTGCTCTCGCTTCTATCGCCCGTCATTA
CGGAGCAAACTATTCTTTAGCCCATTTGCGTGAACTGGCCAAGACGGATAAGGAGGGGACAACAGCTTTGGGTATTGTGG
AAGCTGCCCAGACCATGGGCTTTGAGACTCGGGCTGTCCGAGCTGATATGAGCCTTTTTGAAGAAGAGGAGATTCCCTAT
CCCTTTATCGCTCATGTCAATAAAGAGGGTAAACTACAACACTACTATGTAGTTTATAAGGCTAAGAAAAATCATCTGAT
TATCGGCGATCCCGATCCAAGTGTCAAAGTAACCAAGATGAGTAAAGAAAGATTTGAACAAGAATGGGATGGTATTTCCA
TTTTCCTAGCTCCAGAGCCAGCCTACAAACCCCATAAGGATAAGAAAAATGGTCTATTGAGTTTCATCCCAATCATTCTC
AAGCAAAAGGGGCTTATCTTCCAGATTAGTTTGGCCAGCCTTTTAGTGACCTTGATTGATATCTTGGGCTCCTACTACTT
ACAAGGGATTCTAGATAGTTATATTCCCAATCAAATGACTTCAACCTTGACCATTGTCTCGCTCGGTCTGGTCATTACCT
ATGTTATTCAGCAAATTATGGCCTTCTCACGGGACTATCTCTTAACAGTTCTCAGTCAGAGGCTCAGTATTGATGTGATC
CTGGCTTATATCCGTCATATCTTTTCCTTGCCCATGTCTTTCTTTGCGACAAGGCGAACGGGGGAGATTACCTCACGTTT
TTCAGATGCCAATTCTATCATTGATGCTCTGGCCTCAACTATTTTGTCCATCTTCTTAGATTGTTTTATTTTAATTATTA
TCGGAGCTGTTCTGCTTCTGCAAAACGCCAATCTCTTCCTCCTAACTTTGCTGTCTATCCCAATCTACACAATTATCATC
CTTGCCTTTATGAAACCCTTTGAAAAAATGAACCAAGATGTCATGGAAGCCAACAGTATGGTTAGCTCTGCTATCATTGA
AGATATCAACGGGATGGAAACCATCAAGTCGCTGACTAGTGAGGATACTCGCTACCGCAATGTTGATAATGAGTTTGTTG
ATTATCTAGATAAGTCCTTTAAACGCCACAAGTACGAAATTTTACAAACTTCCCTTAAAAAGGGAGCCCAGCTGATTTTA
AATGTCGCCATCCTCTGGTTTGGCTCAACACTGGTTATGGTCAATAAGATCTCCATTGGTCAACTCGTTGCCTATAATTC
TCTCTTAACCTACTTTACCAATCCGCTGGAAAACATCATCAACTTACAAACCAAGCTGCAATCGGCCAAAGTAGCCAATA
ATCGGCTCAATGAAGTTTACCTTGTTTCCTCGGAATTCGACCAGAAAACTACGAAAGTTAATCAAGAGGCTCCGTCTGGA
GATATTGTCTTTTCTGATGTCTCCTACAAATACGGGTTCGGTCGAGATACCCTGACCGACATTAACCTTAAAATTGCCAA
AGGTTCGAAAATCAGCTTGGTCGGTATCAGTGGCTCTGGGAAAACGACGCTGGCTAAACTGATTGTCAACTTTTTCCAAC
CCTACAAGGGAGAAATCACTATTAAGAGCCTAAATACCAACCTTTTGGATAAAAGGCTTCTTCGCAAATATATCAACTAC
CTACCTCAGCAACCTTATGTCTTTTCCGGAAGCATCTTAGAAAATTTGACTTTAGGTGCCGACGAGTCTGTCAGTCAAGA
GGACATCATGAAAGCCTGTGAGATGGCTGAAATCAGAAGAGATATCGAGCAAATGCCACTGGGTTATCAAACTGAGCTAT
CCGATGGGGCGGGACTCTCAGGTGGTCAAAAACAAAGGATAGCTCTGGCACGTGCCCTCCTGACAAAGTCACCGATTATG
GTCTTAGACGAAGCGACTAGCGGGCTAGATGTCTTAACAGAAAAAAAGGTCATTGACAACCTGATGAAGATGACCGAGAA
AACCATTATTTTTGTGGCCCACCGACTCAGCATTTCTGAGCGGACTGACAAAATTGTTGTTCTTGACCAGGGAAGAATTA
TTGAAACAGGTTCCCATCAGGATTTGCTTAAAAAGCAAGGCTTCTACTACCAACTTTTTAATAAATAA

Domains

Predicted by InterproScan.

• Peptidase C39 family (Peptidase_C39) (4-140)

• ABC transporter transmembrane region (ABC_membrane) (170-436)

• ABC transporter (ABC_tran) (498-647)

3D structure

• AlphaFold DB: U2KIX5

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA/nlmT	Streptococcus mutans UA159	70.464	99.441	0.701
comA	Streptococcus mitis NCTC 12261	65.83	100	0.66
comA	Streptococcus mitis SK321	65.551	100	0.657
comA	Streptococcus pneumoniae TIGR4	65.272	100	0.655
comA	Streptococcus pneumoniae R6	65.272	100	0.655
comA	Streptococcus pneumoniae Rx1	65.272	100	0.655
comA	Streptococcus pneumoniae D39	65.272	100	0.655
comA	Streptococcus gordonii str. Challis substr. CH1	65.132	100	0.653