Detailed information NTG0293216

Bioinformatically predicted

Overview

• Name: comA/nlmT
• Type: Regulator
• Locus tag: DK182_RS06050
• Genome accession: NZ_CP029491
• Coordinates: 1203366..1205513 (+)
• Length: 715 a.a.
• NCBI ID: WP_109833593.1
• Uniprot ID: -
• Organism: Streptococcus sobrinus strain 10919
• Function: transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 1198366..1210513

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DK182_RS06010 (DK181_06010)	-	1199058..1199468 (-)	411	WP_019771643.1	hypothetical protein	-
DK182_RS06015 (DK181_06015)	-	1199500..1199643 (-)	144	WP_019768643.1	hypothetical protein	-
DK182_RS06020 (DK181_06020)	-	1199923..1200825 (+)	903	Protein_1125	IS256 family transposase	-
DK182_RS06025 (DK181_06025)	-	1200919..1201842 (+)	924	Protein_1126	IS30 family transposase	-
DK182_RS06030 (DK181_06030)	-	1201869..1202147 (+)	279	Protein_1127	transposase	-
DK182_RS06035 (DK181_06035)	-	1202396..1202581 (-)	186	WP_019770704.1	hypothetical protein	-
DK182_RS06040 (DK181_06040)	-	1202609..1202800 (-)	192	WP_019770705.1	Blp family class II bacteriocin	-
DK182_RS06045 (DK181_06045)	-	1202857..1203051 (-)	195	WP_019771729.1	bacteriocin class II family protein	-
DK182_RS06050 (DK181_06050)	comA/nlmT	1203366..1205513 (+)	2148	WP_109833593.1	peptide cleavage/export ABC transporter	Regulator
DK182_RS06055 (DK181_06055)	-	1205526..1206299 (+)	774	WP_019770708.1	HlyD family efflux transporter periplasmic adaptor subunit	-
DK182_RS06060 (DK181_06060)	-	1206417..1207763 (-)	1347	WP_019770709.1	sensor histidine kinase	-
DK182_RS06065 (DK181_06065)	-	1207766..1208509 (-)	744	WP_109833594.1	response regulator transcription factor	-
DK182_RS06070 (DK181_06070)	-	1208624..1209127 (-)	504	WP_019768650.1	phosphatase PAP2 family protein	-
DK182_RS06075 (DK181_06075)	-	1209833..1210360 (-)	528	WP_019777343.1	YbaK/EbsC family protein	-

Sequence

Protein

• Length: 715 a.a.
• Molecular weight: 80428.65 Da
• Isoelectric Point: 8.6469

>NTDB_id=293216 DK182_RS06050 WP_109833593.1 1203366..1205513(+) (comA/nlmT) [Streptococcus sobrinus strain 10919]
MNFYKFVPQIDARDCGVAALASIARHYGANYSLAHLRELAKTDKEGTTALGIVEAAKTMGFETRAVRADMSLFEEEEIPY
PFIAHVNKEGKLQHYYVVYKAKKNHLIIGDPDPSVKVTKMSKERFEQEWDGISIFLAPEPAYKPHKDKKNGLLSFIPIIL
KQKGLIFQISLASLLVTLIDILGSYYLQGILDSYIPNQMTSTLTIVSLGLVITYVIQQIMAFSRDYLLTVLSQRLSIDVI
LAYIRHIFSLPMSFFATRRTGEMTSRFSDANSIIDALASTILSIFLDCFILIIIGAVLLLQNANLFLLTLLSIPIYTIII
LVFMKPFEKMNQDVMEANSMVSSAIIEDINGMETIKSLTSEDTRYRNVDNEFVDYLDKSFKRHKYEILQTSLKKGAQLIL
NVAILWFGSTLVMVNKISIGQLVAYNSLLTYFTNPLENIINLQTKLQSAKVANNRLNEVYLVSSEFDQKTTKVNQEALSG
DIVFSDVSYKYGFGRDTLTDINLKIAKGSKISLVGISGSGKTTLAKLIVNFFQPYKGEITIKSLNTNLLDKRLLRKYINY
LPQQPYVFSGSILENLTLGANESVSQEDIMKACEMAEIRRDIEQMPLGYQTELSDGAGLSGGQKQRIALARALLTKSPIM
VLDEATSGLDVLTEKKVIDNLMKMTEKTIIFVAHRLSISERTDKIVVLDQGRIIETGPHQDLLKKQGFYYQLFNK

Nucleotide

• Length: 2148 bp

>NTDB_id=293216 DK182_RS06050 WP_109833593.1 1203366..1205513(+) (comA/nlmT) [Streptococcus sobrinus strain 10919]
ATGAATTTTTACAAATTTGTTCCTCAGATTGATGCCAGAGACTGTGGAGTTGCTGCTCTCGCTTCTATCGCCCGTCATTA
CGGGGCCAACTATTCTTTAGCCCATTTGCGTGAACTGGCCAAGACGGATAAGGAGGGGACAACGGCTTTAGGTATCGTAG
AAGCGGCCAAAACCATGGGTTTTGAGACTCGGGCTGTCCGAGCTGATATGAGCCTTTTTGAAGAAGAGGAGATTCCCTAT
CCCTTTATCGCTCATGTCAATAAAGAGGGTAAACTACAACACTACTATGTAGTTTATAAGGCTAAGAAAAATCATCTGAT
TATCGGCGATCCCGATCCAAGTGTCAAAGTAACCAAGATGAGTAAAGAAAGGTTTGAACAAGAATGGGATGGTATTTCCA
TTTTCCTAGCTCCAGAGCCAGCCTACAAACCCCATAAGGATAAGAAAAATGGTCTATTGAGTTTCATCCCAATCATTCTC
AAGCAAAAGGGGCTTATCTTCCAGATTAGTTTGGCCAGCCTTTTAGTGACCTTGATTGATATCTTGGGCTCCTACTACTT
ACAAGGGATTCTAGATAGTTATATTCCCAATCAAATGACTTCAACCTTGACCATTGTCTCGCTCGGTCTGGTCATTACCT
ATGTTATTCAGCAAATTATGGCCTTCTCACGGGACTATCTCTTAACAGTTCTCAGTCAGAGGCTCAGTATTGATGTGATC
CTGGCTTATATCCGTCATATCTTTTCCTTGCCCATGTCTTTCTTTGCGACAAGGCGAACGGGGGAGATGACCTCACGTTT
TTCAGATGCCAATTCTATCATTGATGCTCTGGCCTCAACTATTTTGTCCATCTTCTTAGATTGTTTTATTTTAATTATTA
TCGGAGCTGTTCTGCTTCTGCAAAACGCCAACCTCTTCCTCCTAACTTTGCTGTCTATCCCAATCTACACAATTATCATC
CTTGTCTTTATGAAACCCTTTGAAAAAATGAACCAAGATGTCATGGAAGCCAACAGTATGGTTAGCTCTGCTATCATTGA
AGATATCAACGGGATGGAAACCATCAAGTCGCTGACTAGTGAGGATACTCGCTACCGCAATGTTGATAATGAGTTTGTTG
ATTATCTAGATAAGTCCTTTAAACGCCACAAGTACGAAATTTTACAAACTTCCCTTAAAAAGGGAGCCCAGCTGATTTTA
AATGTCGCCATCCTCTGGTTTGGCTCAACACTGGTTATGGTCAATAAGATCTCCATTGGTCAACTCGTTGCCTATAATTC
TCTCTTAACCTACTTTACCAATCCGCTGGAAAACATCATCAACTTACAAACCAAGCTGCAATCGGCCAAAGTAGCCAATA
ATCGGCTCAATGAAGTTTACCTTGTTTCCTCGGAATTCGACCAGAAAACTACGAAAGTTAATCAGGAGGCTCTGTCTGGA
GATATTGTCTTTTCTGATGTCTCCTACAAATACGGGTTCGGTCGAGATACCCTGACCGACATTAACCTTAAAATTGCCAA
AGGTTCGAAAATCAGCTTGGTCGGTATCAGTGGCTCTGGGAAAACGACGCTGGCTAAACTGATTGTCAACTTTTTCCAAC
CCTACAAGGGAGAAATCACTATTAAGAGCCTAAATACCAACCTTTTGGATAAAAGGCTTCTTCGCAAATATATCAACTAC
CTACCTCAGCAACCTTATGTCTTTTCCGGAAGCATCTTAGAAAATTTGACTTTAGGTGCCAACGAGTCTGTCAGTCAAGA
GGACATCATGAAAGCCTGTGAGATGGCTGAAATCAGAAGAGATATCGAGCAAATGCCACTGGGTTATCAAACTGAGCTAT
CCGATGGGGCGGGACTCTCAGGTGGTCAAAAACAAAGGATAGCTCTGGCACGTGCCCTCCTGACAAAGTCACCGATTATG
GTCTTAGACGAAGCGACTAGCGGGCTAGATGTCTTAACAGAAAAAAAGGTCATTGACAACCTGATGAAGATGACCGAGAA
AACCATTATTTTTGTGGCCCACCGACTCAGCATTTCTGAGCGGACTGACAAAATTGTTGTTCTTGACCAGGGAAGAATTA
TTGAAACAGGTCCCCATCAGGATTTGCTTAAAAAGCAAGGCTTCTACTACCAACTTTTTAATAAATAA

Domains

Predicted by InterproScan.

• Peptidase C39 family (Peptidase_C39) (4-140)

• ABC transporter transmembrane region (ABC_membrane) (170-436)

• ABC transporter (ABC_tran) (498-647)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA/nlmT	Streptococcus mutans UA159	70.464	99.441	0.701
comA	Streptococcus mitis NCTC 12261	65.551	100	0.657
comA	Streptococcus mitis SK321	65.272	100	0.655
comA	Streptococcus pneumoniae TIGR4	64.993	100	0.652
comA	Streptococcus pneumoniae R6	64.993	100	0.652
comA	Streptococcus pneumoniae Rx1	64.993	100	0.652
comA	Streptococcus pneumoniae D39	64.993	100	0.652
comA	Streptococcus gordonii str. Challis substr. CH1	64.854	100	0.65