Detailed information    

insolico Bioinformatically predicted

Overview

Name   stkP   Type   Regulator
Locus tag   DF184_RS02190 Genome accession   NZ_CP029398
Coordinates   426879..428873 (+) Length   664 a.a.
NCBI ID   WP_044679956.1    Uniprot ID   A0AAN2RHI4
Organism   Streptococcus suis strain HN105     
Function   require for competence development; phosphorylate ComE (predicted from homology)   
Competence regulation

Genomic Context

Location: 421879..433873
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DF184_RS02175 (DF184_02175) fmt 423866..424804 (+) 939 WP_109371171.1 methionyl-tRNA formyltransferase -
  DF184_RS02180 (DF184_02180) rsmB 424791..426104 (+) 1314 WP_079268066.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  DF184_RS02185 (DF184_02185) - 426142..426879 (+) 738 WP_004194145.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  DF184_RS02190 (DF184_02190) stkP 426879..428873 (+) 1995 WP_044679956.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  DF184_RS02195 (DF184_02195) liaF 429198..429857 (+) 660 WP_239425118.1 cell wall-active antibiotics response protein LiaF -
  DF184_RS02200 (DF184_02200) - 429854..430870 (+) 1017 WP_002937028.1 sensor histidine kinase -
  DF184_RS02205 (DF184_02205) - 430842..431483 (+) 642 WP_002937025.1 response regulator transcription factor -
  DF184_RS02210 (DF184_02210) - 431533..432933 (+) 1401 WP_024377222.1 Cof-type HAD-IIB family hydrolase -
  DF184_RS02215 (DF184_02215) - 432935..433306 (+) 372 WP_002937017.1 S1 RNA-binding domain-containing protein -

Sequence

Protein


Download         Length: 664 a.a.        Molecular weight: 71393.96 Da        Isoelectric Point: 6.3011

>NTDB_id=292265 DF184_RS02190 WP_044679956.1 426879..428873(+) (stkP) [Streptococcus suis strain HN105]
MIQIGKIFAGRYRIVRQIGRGGMADVYLARDLILDGEEVAVKVLRTNYQTDQIAIQRFQREARAMAELDHPNIVRISDIG
EEDGQQYLAMEYVNGLDLKRYIKENAPLSNDVAVRIMGQILLAMRMAHTRGIVHRDLKPQNVLLTSNGVAKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATIQSDIYAMGIILFEMLTGRIPYDGDSAVTIALQHFQKPLPSVREENANVP
QALENVVLKATAKKLNERYKSVAEMYADLASALSMDRRNEPRVELEGNKVDTKTLPKLSQANVETKVPHTNSSAQVSATD
KGPGKKEVAKSGNKPVSKPRPGMRTRYKVLIGAILLTVIAAGLMFFNTPRTVTVPDVSGQTVEKATEMIEVAGLEVGNIT
EEATATVDEGLVIRTSPAAKTTRRQGSKIDIVVATAAMVSIPDVTDKDSDTARQELEALGFQVTIKEEYSEKVAQGLVIK
TDPGANSSAEKGAKITLYVSKGVAPQVVPNVVGKTQENATQILQTAGFSIGTITQEYSSSVTAGQVISTDPVANTELTKG
SIINLVVSKGKELIMPDLTSGNYTYSQARSQLQALGVNVESIEKQEDRSYYSTTSDIVIGQYPAAGATIDGTVTLYVSVA
STGTSSDSSTGSSTSTSTSTDSGQ

Nucleotide


Download         Length: 1995 bp        

>NTDB_id=292265 DF184_RS02190 WP_044679956.1 426879..428873(+) (stkP) [Streptococcus suis strain HN105]
ATGATTCAAATCGGTAAGATCTTTGCCGGTCGGTATCGAATCGTTCGGCAAATTGGTCGAGGCGGTATGGCAGATGTTTA
CCTAGCAAGAGATTTGATTTTAGATGGAGAAGAGGTTGCCGTTAAAGTTCTTCGGACCAACTATCAGACAGATCAAATTG
CTATCCAGCGTTTTCAACGTGAAGCGCGTGCCATGGCAGAACTTGACCATCCCAATATCGTTCGTATTTCGGACATCGGC
GAAGAAGATGGTCAACAGTATCTGGCTATGGAATATGTCAATGGCCTCGATTTAAAACGTTATATAAAAGAAAATGCACC
ACTCTCCAACGATGTTGCGGTGCGAATTATGGGACAGATTCTCCTTGCTATGCGAATGGCGCACACGAGAGGAATTGTCC
ATCGAGATTTGAAACCTCAGAACGTCCTTTTGACTTCCAATGGAGTCGCTAAAGTAACAGACTTTGGTATTGCAGTTGCC
TTCGCTGAAACGAGTTTGACACAAACCAACTCCATGTTGGGTTCTGTTCACTATCTTTCACCTGAGCAGGCGCGTGGTTC
GAAAGCGACCATTCAAAGTGACATTTATGCGATGGGAATCATCCTTTTTGAAATGTTGACGGGTCGCATTCCCTATGATG
GAGACAGTGCTGTGACGATCGCTCTTCAGCATTTCCAAAAACCTCTCCCATCTGTTAGAGAAGAGAACGCCAACGTACCT
CAGGCCTTAGAAAATGTTGTGCTAAAAGCAACGGCAAAAAAATTAAACGAGCGCTATAAGTCGGTTGCAGAAATGTACGC
AGATTTAGCTTCGGCTCTATCCATGGATCGTCGGAATGAACCCAGGGTTGAACTAGAAGGGAACAAGGTTGATACAAAAA
CCTTGCCAAAACTCTCCCAAGCCAATGTTGAAACGAAAGTACCGCATACAAACAGTTCTGCCCAAGTTTCTGCGACGGAT
AAGGGGCCTGGTAAGAAAGAAGTGGCGAAGTCGGGAAATAAGCCTGTTTCAAAACCAAGGCCAGGTATGCGTACACGCTA
CAAAGTCTTGATAGGGGCTATTTTGTTAACAGTCATAGCGGCTGGACTCATGTTTTTCAACACTCCACGAACAGTTACCG
TCCCTGATGTGTCTGGTCAAACCGTTGAAAAAGCTACAGAAATGATTGAAGTGGCAGGATTGGAAGTTGGAAACATCACA
GAAGAAGCGACAGCGACTGTAGATGAAGGCTTGGTAATACGGACCTCTCCGGCTGCAAAGACGACCAGACGTCAAGGAAG
TAAGATTGATATTGTAGTAGCAACGGCTGCGATGGTATCTATTCCAGATGTGACAGATAAGGATTCTGATACTGCACGGC
AGGAATTGGAGGCTCTTGGTTTCCAAGTGACAATAAAAGAAGAATATAGCGAAAAAGTTGCCCAAGGTCTCGTTATCAAA
ACAGATCCAGGAGCAAATAGTTCTGCTGAGAAGGGGGCGAAAATTACCCTTTACGTTTCCAAAGGAGTAGCGCCACAAGT
TGTTCCAAACGTTGTTGGAAAAACTCAGGAGAATGCTACTCAAATTCTTCAGACAGCAGGCTTCAGTATTGGAACTATTA
CTCAGGAATATAGCTCATCTGTTACTGCGGGTCAGGTTATCAGTACAGATCCCGTTGCCAATACAGAGTTGACAAAAGGT
TCTATCATCAATCTAGTTGTTTCAAAAGGAAAAGAATTGATTATGCCTGATTTAACATCTGGCAATTACACTTACTCACA
GGCACGTAGTCAATTACAAGCACTGGGTGTCAATGTGGAAAGTATTGAAAAACAAGAAGATAGAAGCTATTATTCAACGA
CAAGTGACATCGTCATTGGACAATATCCTGCTGCTGGCGCAACAATTGATGGAACAGTTACCTTGTATGTCTCCGTTGCA
TCAACCGGCACCAGTAGCGATTCCTCAACAGGAAGTTCCACTAGCACAAGTACTTCAACAGATAGCGGACAATAA

Domains

Predicted by InterproScan.

Protein kinase domain (Pkinase)

(12-240)

PASTA domain (PASTA)

(507-569)

PASTA domain (PASTA)

(372-434)

PASTA domain (PASTA)

(440-501)

PASTA domain (PASTA)

(574-638)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  stkP Streptococcus pneumoniae TIGR4

53.241

97.59

0.52
  stkP Streptococcus pneumoniae D39

53.086

97.59

0.518
  stkP Streptococcus pneumoniae R6

53.086

97.59

0.518
  stkP Streptococcus pneumoniae Rx1

52.932

97.59

0.517
  stkP/pknB Streptococcus salivarius strain HSISS4

52.65

88.102

0.464
  pknB Streptococcus mutans UA159

54.953

80.572

0.443

Multiple sequence alignment