Detailed information    

insolico Bioinformatically predicted

Overview

Name   stkP   Type   Regulator
Locus tag   DG474_RS07550 Genome accession   NZ_CP029257
Coordinates   1553868..1555769 (-) Length   633 a.a.
NCBI ID   WP_070683772.1    Uniprot ID   -
Organism   Streptococcus oralis strain CCUG 53468     
Function   require for competence development; phosphorylate ComE (predicted from homology)   
Competence regulation

Genomic Context

Location: 1548868..1560769
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DG474_RS07525 (DG474_07655) - 1548885..1549850 (+) 966 WP_255777946.1 LacI family DNA-binding transcriptional regulator -
  DG474_RS07530 (DG474_07660) - 1550001..1551275 (-) 1275 WP_255777952.1 hydroxymethylglutaryl-CoA reductase, degradative -
  DG474_RS07535 (DG474_07665) - 1551275..1552447 (-) 1173 WP_255778968.1 hydroxymethylglutaryl-CoA synthase -
  DG474_RS07540 (DG474_07670) - 1552566..1553021 (-) 456 WP_000176902.1 threonine/serine exporter family protein -
  DG474_RS07545 (DG474_07675) - 1553023..1553781 (-) 759 WP_255777955.1 threonine/serine exporter family protein -
  DG474_RS07550 (DG474_07680) stkP 1553868..1555769 (-) 1902 WP_070683772.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  DG474_RS07555 (DG474_07685) - 1555766..1556506 (-) 741 WP_000401527.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  DG474_RS07560 (DG474_07690) rsmB 1556522..1557835 (-) 1314 WP_255777959.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  DG474_RS07565 (DG474_07695) fmt 1557828..1558763 (-) 936 WP_255777960.1 methionyl-tRNA formyltransferase -

Sequence

Protein


Download         Length: 633 a.a.        Molecular weight: 68880.12 Da        Isoelectric Point: 8.9709

>NTDB_id=291430 DG474_RS07550 WP_070683772.1 1553868..1555769(-) (stkP) [Streptococcus oralis strain CCUG 53468]
MIQIGKIFAGRYRIVKQIGRGGMADVYLAKDLILDGEEVAVKVLRTNYQTDPIAVARFQREARAMADLDHPHIVRITDIG
EEDGQQYLAMEYVAGLDLKRYIKEHYPLSNEEAVRIMGQILLAMRLAHTRGIVHRDLKPQNILLTPDGTAKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATFQSDIYAMGIIFYEMLTGHIPYDGDSAVTIALQHFQKPLPSVIAENPSVP
QALENVVIKATAKKLSDRYQSVSEMYVDLSTSLSYNRRNEPKLVFDDASKADTKTLPKVPQSTLTSIPKAPAQEERPQPK
KSTQPVAEPAPAPKPAKKRKFKARYMILLASLLLVAASLVWILSRTPATIPIPDVAGQTVAEAKEALKKSKFEAGEEKSE
ASDTVAEGRVIRTDPEAGSGRKEGTKVNLIVSSGKQSFQLSNYVGRKYTEVVAELKEKKVPENLIKMEEEESNESEPGIV
LRQTPASGSTYDLSKATTITLTVAKKVTSVSMPNYIGSSLEFTKNNLTQIVGVKEANIEVVEVSTAPEGTAEGTVVSQTP
RAGEQVDLASTRIKLSIYKPKTPPSTSSSNPAQRGNQGSPTSPNQGNQQGNQQGNTPSSSSSNSEGTHESSRD

Nucleotide


Download         Length: 1902 bp        

>NTDB_id=291430 DG474_RS07550 WP_070683772.1 1553868..1555769(-) (stkP) [Streptococcus oralis strain CCUG 53468]
ATGATCCAAATCGGCAAGATTTTTGCCGGGCGGTATCGGATTGTCAAGCAGATTGGTCGAGGAGGCATGGCAGATGTATA
CTTGGCCAAGGATTTGATCCTAGACGGGGAAGAAGTTGCAGTGAAGGTCCTGAGGACCAACTACCAGACGGACCCGATTG
CTGTGGCACGTTTCCAGCGTGAAGCGAGAGCCATGGCGGATCTGGACCATCCTCATATCGTTCGGATAACAGATATTGGT
GAGGAAGATGGTCAACAGTACCTAGCTATGGAATACGTAGCAGGCCTTGACCTCAAGCGTTATATCAAAGAACACTATCC
TCTTTCAAATGAAGAAGCAGTTCGGATCATGGGGCAAATCCTCTTGGCCATGCGCTTAGCCCATACTCGAGGAATTGTTC
ACCGGGATTTGAAACCTCAAAATATCCTCTTGACACCTGACGGCACAGCTAAGGTCACGGACTTTGGGATTGCTGTAGCC
TTTGCGGAGACTAGTCTGACCCAGACCAACTCAATGTTAGGCTCTGTTCATTATTTGTCACCTGAGCAAGCACGTGGATC
TAAAGCGACCTTCCAGAGTGATATCTATGCAATGGGGATTATCTTCTATGAAATGCTGACTGGTCATATTCCTTACGATG
GGGATAGTGCAGTTACGATTGCTCTCCAGCATTTCCAGAAGCCACTTCCGTCCGTCATAGCTGAAAATCCATCTGTCCCT
CAGGCTTTAGAAAATGTTGTCATCAAGGCAACTGCTAAGAAGCTGTCAGATCGTTATCAGTCTGTTTCAGAAATGTATGT
GGACTTGTCAACTAGCTTGTCTTATAATCGTCGGAATGAACCGAAATTGGTCTTTGACGATGCGAGTAAGGCAGACACTA
AGACTTTACCTAAAGTTCCACAAAGTACACTGACATCGATTCCTAAAGCTCCGGCGCAAGAAGAACGCCCTCAACCAAAG
AAATCAACTCAACCAGTCGCAGAGCCAGCTCCAGCGCCAAAGCCTGCCAAGAAACGGAAGTTTAAGGCTCGCTATATGAT
TCTTTTGGCCAGTCTTCTATTGGTTGCAGCCTCTTTGGTCTGGATTTTGTCAAGAACACCAGCAACGATTCCTATTCCTG
ACGTAGCCGGACAAACTGTTGCAGAGGCTAAGGAAGCTCTTAAAAAATCCAAGTTTGAAGCCGGTGAAGAAAAGTCAGAG
GCCAGCGATACAGTAGCAGAAGGACGAGTTATTCGAACGGATCCAGAAGCTGGTAGCGGCCGAAAAGAAGGAACCAAGGT
CAATTTGATTGTTTCTTCTGGTAAGCAATCCTTCCAATTGAGCAATTATGTCGGACGTAAGTATACGGAAGTTGTAGCTG
AACTCAAGGAGAAGAAGGTTCCTGAAAATCTAATCAAGATGGAAGAGGAAGAATCCAATGAAAGCGAACCTGGAATCGTC
CTCAGACAGACCCCTGCTTCGGGTTCGACCTATGATCTCTCAAAAGCCACTACGATTACCTTAACAGTAGCTAAGAAGGT
GACTAGTGTCAGCATGCCGAACTACATCGGTTCAAGTCTCGAGTTTACAAAGAATAACTTGACTCAGATTGTCGGTGTGA
AGGAAGCAAATATTGAGGTTGTTGAAGTATCGACTGCTCCTGAAGGAACGGCAGAAGGAACTGTTGTCAGTCAAACGCCA
AGAGCAGGAGAACAGGTTGATCTTGCAAGTACGCGTATCAAACTTTCCATCTACAAACCAAAAACACCACCATCAACTTC
ATCCTCTAATCCTGCCCAACGTGGGAACCAAGGTTCTCCTACAAGTCCAAACCAGGGGAACCAACAAGGAAATCAACAAG
GGAATACTCCTTCTAGCAGTTCATCCAATAGTGAAGGAACTCACGAGAGTTCTCGAGATTAG

Domains

Predicted by InterproScan.

PASTA domain (PASTA)

(441-505)

PASTA domain (PASTA)

(510-579)

PASTA domain (PASTA)

(372-432)

Protein kinase domain (Pkinase)

(12-227)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  stkP Streptococcus pneumoniae TIGR4

78.328

92.575

0.725
  stkP Streptococcus pneumoniae D39

77.986

92.575

0.722
  stkP Streptococcus pneumoniae R6

77.986

92.575

0.722
  stkP Streptococcus pneumoniae Rx1

77.816

92.575

0.72
  pknB Streptococcus mutans UA159

56.153

91.153

0.512
  stkP/pknB Streptococcus salivarius strain HSISS4

53.311

93.049

0.496

Multiple sequence alignment