Detailed information NTG0291423

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: DG474_RS06015
• Genome accession: NZ_CP029257
• Coordinates: 1222228..1224468 (-)
• Length: 746 a.a.
• NCBI ID: WP_200371573.1
• Uniprot ID: -
• Organism: Streptococcus oralis strain CCUG 53468
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1217228..1229468

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DG474_RS05995 (DG474_06105)	-	1218996..1220660 (-)	1665	WP_255777667.1	molecular chaperone HscC	-
DG474_RS06000 (DG474_06110)	rplT	1220834..1221193 (-)	360	WP_000124830.1	50S ribosomal protein L20	-
DG474_RS06005 (DG474_06115)	rpmI	1221245..1221445 (-)	201	WP_001125942.1	50S ribosomal protein L35	-
DG474_RS06010 (DG474_06120)	infC	1221478..1222008 (-)	531	WP_000848184.1	translation initiation factor IF-3	-
DG474_RS06015 (DG474_06125)	comEC/celB	1222228..1224468 (-)	2241	WP_200371573.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
DG474_RS06020 (DG474_06130)	comEA/celA/cilE	1224452..1225102 (-)	651	WP_125397719.1	helix-hairpin-helix domain-containing protein	Machinery gene
DG474_RS06025 (DG474_06135)	-	1225169..1225738 (-)	570	WP_255777670.1	GNAT family N-acetyltransferase	-
DG474_RS06030 (DG474_06145)	ald	1225914..1227026 (+)	1113	WP_255777671.1	alanine dehydrogenase	-
DG474_RS06035 (DG474_06150)	-	1227077..1228063 (-)	987	WP_084921953.1	PhoH family protein	-
DG474_RS06040 (DG474_06155)	-	1228144..1228359 (-)	216	WP_001232084.1	YozE family protein	-
DG474_RS06045 (DG474_06160)	-	1228356..1228961 (-)	606	WP_255777672.1	GrpB family protein	-

Sequence

Protein

• Length: 746 a.a.
• Molecular weight: 84789.07 Da
• Isoelectric Point: 9.2887

>NTDB_id=291423 DG474_RS06015 WP_200371573.1 1222228..1224468(-) (comEC/celB) [Streptococcus oralis strain CCUG 53468]
MSQRIKNFPIPLIYLSFLLLWLYFVILGASYLALLGFVFLLVCLFFQFPWKSAGKVLAICGVFGIWFLFQNWQQTQASQN
LVDSVERVRILPDTIKVNGDSLSFRGKAEGRTFQVYYKLQSEEEKELFQALTDLHEIELEGKLSEPEGQRNFGGFDYRAY
LKTQGIYQTLTIKSIQSLKQVSSWDIGENLSALRRKAVVWIKAHFPDPMRNYMTGLLLGHLDTDFEEMNELYSSLGIIHL
FALSGMQVGFFMEAFKKLLLRLGLTQEKLKWLTYPFSLIYAGLTGFSASVIRSLLQKLLAQHGVKGLDNFALTILVLFII
MPNFFLTAGGVLSCAYAFILTMTSKEGDGIKAVARESLVISLGILPILSFYFAEFQPWSILLTFVFSFLFDVVFLPLLSI
LFILSFIYSVTQFNFVFEWLENIIRLVSQLASRPLVLGQPTTWLLILLLVSLALLYDMRKNIKRLAGFSLFIVGLFFLTK
HPLENEITMLDVGQGESIFLRDVTGKTILIDVGGKAESDKKIEAWQEKSTTSNAQRTLIPYLKSRGVDKIDQLILTNTDK
EHVGDLLEVTKAFHVGEILVSKGSLTQKEFVAELEASQNKVRSVTAGEYFPIFGSYLEVLSPRQIRDGNRDDSLVLYGKL
LDKHFFFTGNLKEKGEKDLMKHYPDLEVDVLKAGQHGAKTSSNPVFLEQLKPAITLISVGKSNRTKLPHQETLTRMESIK
SKIYRTDQQGAIRFKGWNSWRIETVR

Nucleotide

• Length: 2241 bp

>NTDB_id=291423 DG474_RS06015 WP_200371573.1 1222228..1224468(-) (comEC/celB) [Streptococcus oralis strain CCUG 53468]
ATGTCACAGCGGATTAAGAATTTCCCTATCCCCTTAATCTATCTGAGTTTTCTGTTACTCTGGCTTTACTTTGTCATTTT
AGGAGCGTCCTATCTCGCACTGCTAGGTTTTGTTTTTTTGCTGGTCTGCCTCTTTTTCCAATTTCCTTGGAAATCGGCTG
GTAAAGTTCTAGCGATTTGTGGAGTTTTTGGAATTTGGTTTTTGTTTCAAAACTGGCAACAGACACAAGCTAGTCAGAAC
CTAGTGGATTCTGTTGAAAGGGTACGGATTTTACCAGATACCATCAAAGTCAATGGAGACAGTCTGTCCTTTCGGGGCAA
GGCTGAGGGCCGCACCTTCCAAGTTTATTATAAACTCCAGTCCGAGGAAGAGAAAGAGCTCTTTCAGGCCTTAACAGACC
TTCACGAGATAGAGCTAGAAGGAAAACTTTCTGAGCCTGAAGGGCAGAGAAATTTTGGTGGATTTGACTACCGAGCCTAT
CTGAAGACTCAGGGAATTTACCAGACACTGACTATCAAGAGCATCCAGTCACTTAAACAGGTTAGCAGTTGGGATATAGG
TGAAAATTTGTCGGCTTTACGTCGAAAGGCTGTAGTTTGGATCAAGGCGCACTTTCCAGACCCTATGCGCAACTATATGA
CGGGGCTCTTGCTGGGACATTTGGACACGGACTTTGAGGAGATGAATGAACTCTATTCCAGTCTTGGAATTATCCATCTC
TTTGCCTTGTCGGGTATGCAGGTGGGCTTCTTTATGGAGGCCTTTAAGAAACTCCTCTTGCGATTGGGCTTGACTCAAGA
GAAGTTGAAGTGGCTAACTTATCCATTTTCTCTTATCTATGCAGGTCTGACAGGATTTTCAGCATCTGTCATTCGCAGTC
TCTTACAAAAGTTACTGGCCCAACATGGTGTTAAAGGTTTGGATAATTTTGCCTTGACGATCCTTGTCCTCTTTATCATC
ATGCCCAACTTTTTCTTGACAGCTGGAGGGGTCTTGTCCTGCGCTTATGCTTTTATCTTGACTATGACTAGCAAAGAAGG
CGATGGGATCAAGGCTGTTGCCAGAGAAAGTCTGGTCATTTCTTTGGGAATATTGCCTATTCTATCCTTCTATTTTGCAG
AATTTCAGCCTTGGTCTATCCTTTTGACCTTTGTCTTTTCCTTTCTGTTTGATGTGGTCTTCTTGCCGCTTTTGTCCATC
TTATTCATTCTGTCTTTTATTTACTCAGTCACTCAGTTTAACTTTGTTTTTGAGTGGTTGGAGAACATCATTCGCTTGGT
ATCGCAGCTGGCAAGTAGGCCCCTGGTCCTTGGTCAACCCACCACATGGCTTTTGATTCTCCTCTTAGTTTCATTAGCCT
TGCTATATGATATGAGGAAAAACATTAAAAGACTAGCAGGATTCAGTCTCTTTATTGTGGGGCTCTTTTTCTTGACCAAG
CATCCACTGGAAAATGAAATCACCATGCTGGATGTGGGGCAAGGTGAAAGTATTTTCCTACGGGATGTGACTGGGAAAAC
TATTCTCATAGATGTAGGTGGTAAGGCAGAATCTGATAAGAAAATCGAGGCTTGGCAAGAAAAGTCGACGACCAGCAATG
CCCAGCGTACCTTGATTCCCTATCTAAAAAGTCGAGGAGTAGACAAGATTGACCAGCTGATTTTGACCAATACAGACAAG
GAGCATGTTGGCGATTTGCTGGAGGTGACCAAGGCTTTCCATGTGGGGGAGATTTTAGTATCAAAAGGAAGTCTGACACA
GAAGGAATTTGTAGCGGAACTAGAAGCAAGTCAAAACAAGGTACGTAGTGTGACAGCTGGGGAGTATTTCCCGATTTTTG
GCAGTTACTTAGAAGTTCTATCTCCAAGGCAGATTCGAGATGGGAATCGTGATGATTCTCTGGTTCTTTATGGAAAACTT
TTGGATAAGCACTTTTTCTTTACTGGAAATTTGAAAGAGAAGGGAGAGAAGGACTTGATGAAGCATTATCCTGACCTAGA
GGTGGATGTCTTGAAAGCAGGCCAACATGGTGCTAAAACCTCATCAAATCCAGTTTTCCTAGAACAGCTCAAACCAGCGA
TTACTCTCATTTCAGTCGGAAAGAGCAATCGTACGAAACTCCCCCATCAGGAAACCTTGACACGAATGGAAAGTATCAAG
AGTAAGATTTACCGAACTGACCAGCAAGGGGCTATCCGCTTTAAAGGATGGAATAGTTGGAGAATTGAAACGGTTCGATA
A

Domains

Predicted by InterproScan.

• Competence protein (Competence) (216-458)

• Metallo-beta-lactamase superfamily (Lactamase_B) (492-636)

• Domain of unknown function (DUF4131) (DUF4131) (29-177)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus mitis SK321	86.863	100	0.869
comEC/celB	Streptococcus mitis NCTC 12261	86.309	99.866	0.862
comEC/celB	Streptococcus pneumoniae TIGR4	85.389	100	0.854
comEC/celB	Streptococcus pneumoniae D39	85.121	100	0.851
comEC/celB	Streptococcus pneumoniae Rx1	85.121	100	0.851
comEC/celB	Streptococcus pneumoniae R6	85.121	100	0.851
comEC	Lactococcus lactis subsp. cremoris KW2	44.669	99.33	0.444