Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   DG474_RS03895 Genome accession   NZ_CP029257
Coordinates   798181..798921 (+) Length   246 a.a.
NCBI ID   WP_049485091.1    Uniprot ID   -
Organism   Streptococcus oralis strain CCUG 53468     
Function   degradation of ComW (predicted from homology)   
Competence regulation

Genomic Context

Location: 793181..803921
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DG474_RS03885 (DG474_03970) - 794005..796533 (+) 2529 WP_255778856.1 MBL fold metallo-hydrolase -
  DG474_RS03890 (DG474_03975) - 796580..798058 (-) 1479 WP_255778857.1 oligosaccharide flippase family protein -
  DG474_RS03895 (DG474_03980) mecA 798181..798921 (+) 741 WP_049485091.1 adaptor protein MecA Regulator
  DG474_RS03900 (DG474_03985) - 799069..800355 (+) 1287 WP_255778858.1 homoserine dehydrogenase -
  DG474_RS03905 (DG474_03990) thrB 800357..801226 (+) 870 WP_044020572.1 homoserine kinase -
  DG474_RS03910 (DG474_04000) msrB 801441..802379 (+) 939 WP_255778859.1 peptide-methionine (R)-S-oxide reductase MsrB -

Sequence

Protein


Download         Length: 246 a.a.        Molecular weight: 28556.32 Da        Isoelectric Point: 4.1097

>NTDB_id=291412 DG474_RS03895 WP_049485091.1 798181..798921(+) (mecA) [Streptococcus oralis strain CCUG 53468]
MKMKQISDTTLKITMTLDDLMDRGMEIADFLVPQEKTEEFFYAILDELEMPDNFLDSGMLSFRVTPKPDKVDVFVTKSKI
DQNLDFEDLADLPDMEELAQMSPDEFLKTLEKSIADKTKDDIEAIQSLEQVEAKEEEQEQADKETESKKEPYIYYILRFS
SLGDLVAFAKTVNYQMETSELYKMNGHYYLTILVDVENHPSPYPAWLLARMREFADDSDISRSVLQEYGQILINHDAVLN
LQKIRS

Nucleotide


Download         Length: 741 bp        

>NTDB_id=291412 DG474_RS03895 WP_049485091.1 798181..798921(+) (mecA) [Streptococcus oralis strain CCUG 53468]
ATGAAGATGAAACAAATTAGTGATACAACACTGAAAATAACGATGACTTTAGATGATTTGATGGATCGAGGAATGGAGAT
TGCGGACTTTCTCGTTCCTCAGGAAAAAACCGAAGAGTTTTTCTATGCTATTTTAGATGAGTTAGAGATGCCAGACAATT
TCTTGGATAGCGGCATGCTGAGTTTCCGCGTGACGCCAAAACCTGATAAGGTGGACGTCTTTGTGACCAAGTCCAAGATT
GACCAAAATCTGGATTTTGAAGATTTGGCGGACTTACCAGACATGGAAGAATTAGCCCAAATGTCGCCGGATGAATTTCT
CAAAACCTTGGAAAAGAGCATTGCAGATAAGACCAAGGACGATATTGAGGCCATTCAATCTCTAGAGCAGGTCGAAGCAA
AGGAAGAAGAGCAAGAGCAGGCAGACAAGGAGACTGAGAGTAAGAAAGAACCTTATATCTACTATATCCTGCGCTTTTCA
AGCCTTGGTGACTTAGTTGCTTTTGCAAAGACGGTTAACTACCAGATGGAAACCTCTGAACTCTATAAGATGAATGGGCA
CTACTATTTGACAATCTTAGTCGATGTGGAAAATCATCCAAGTCCATATCCGGCTTGGCTCTTGGCTCGTATGCGTGAGT
TTGCAGACGACAGTGACATCAGTCGTTCAGTCTTGCAAGAGTATGGGCAAATCTTGATCAATCACGATGCAGTTCTTAAT
CTGCAAAAGATTCGTTCATAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-239)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus pneumoniae Rx1

90.574

99.187

0.898
  mecA Streptococcus pneumoniae D39

90.574

99.187

0.898
  mecA Streptococcus pneumoniae R6

90.574

99.187

0.898
  mecA Streptococcus pneumoniae TIGR4

90.164

99.187

0.894
  mecA Streptococcus thermophilus LMD-9

48.016

100

0.492
  mecA Streptococcus thermophilus LMG 18311

47.619

100

0.488
  mecA Streptococcus mutans UA159

48.361

99.187

0.48

Multiple sequence alignment