Detailed information    

insolico Bioinformatically predicted

Overview

Name   cclA/cilC   Type   Machinery gene
Locus tag   DG474_RS02485 Genome accession   NZ_CP029257
Coordinates   491963..492625 (-) Length   220 a.a.
NCBI ID   WP_084881660.1    Uniprot ID   A0A1X1HZ74
Organism   Streptococcus oralis strain CCUG 53468     
Function   processing and translocation of ComGC; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 486963..497625
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DG474_RS02455 (DG474_02515) trpC 487128..487895 (+) 768 WP_255778720.1 indole-3-glycerol phosphate synthase TrpC -
  DG474_RS02460 (DG474_02520) - 487882..488481 (+) 600 WP_255778721.1 phosphoribosylanthranilate isomerase -
  DG474_RS02465 (DG474_02525) trpB 488459..489682 (+) 1224 WP_255778722.1 tryptophan synthase subunit beta -
  DG474_RS02470 (DG474_02530) trpA 489675..490451 (+) 777 WP_255778723.1 tryptophan synthase subunit alpha -
  DG474_RS02475 (DG474_02535) - 490541..491440 (-) 900 WP_084881659.1 YafY family protein -
  DG474_RS02480 (DG474_02540) - 491519..491974 (+) 456 WP_000682684.1 effector binding domain-containing protein -
  DG474_RS02485 (DG474_02545) cclA/cilC 491963..492625 (-) 663 WP_084881660.1 A24 family peptidase Machinery gene
  DG474_RS02490 (DG474_02550) - 492695..493150 (+) 456 WP_084881661.1 GNAT family N-acetyltransferase -
  DG474_RS02495 (DG474_02555) - 493254..493778 (+) 525 WP_125414323.1 thiol-disulfide isomerase -
  DG474_RS02500 (DG474_02560) - 493849..494370 (+) 522 WP_000493727.1 hypothetical protein -
  DG474_RS02505 (DG474_02565) - 494587..494790 (-) 204 WP_000102421.1 CsbD family protein -
  DG474_RS02510 (DG474_02570) - 494832..495416 (-) 585 WP_125422050.1 Asp23/Gls24 family envelope stress response protein -
  DG474_RS02515 (DG474_02575) - 495428..495598 (-) 171 WP_045616759.1 DUF2273 domain-containing protein -
  DG474_RS02520 (DG474_02580) amaP 495610..496173 (-) 564 WP_255778724.1 alkaline shock response membrane anchor protein AmaP -
  DG474_RS02525 (DG474_02585) - 496273..496509 (-) 237 WP_042768735.1 GlsB/YeaQ/YmgE family stress response membrane protein -

Sequence

Protein


Download         Length: 220 a.a.        Molecular weight: 25369.71 Da        Isoelectric Point: 8.1554

>NTDB_id=291407 DG474_RS02485 WP_084881660.1 491963..492625(-) (cclA/cilC) [Streptococcus oralis strain CCUG 53468]
MIDLYFFLVGSILASFLGLVIDRFPEQSIIRPASHCDSCQTRLRPLDLIPILSQVFNRFRCRYCKIRYPFWYALFELGLG
ILFLAWSWGWISLGQIILITAGLTLGIYDFRHQEYPLLVWMTFHLILMAFCGWNLVMVFFIILGIMAHFIDIRMGAGDFL
FLASCALVFSVTELLILIQFASAAGILAFLLQKKKERLPFVPFLLLAATIIIFYQFLLVC

Nucleotide


Download         Length: 663 bp        

>NTDB_id=291407 DG474_RS02485 WP_084881660.1 491963..492625(-) (cclA/cilC) [Streptococcus oralis strain CCUG 53468]
ATGATTGATCTTTATTTTTTTCTTGTCGGGAGCATTCTCGCTTCTTTCTTGGGTTTGGTCATTGACCGTTTTCCTGAGCA
ATCCATTATCCGACCAGCTAGTCACTGCGATTCCTGTCAGACTCGCTTGCGTCCGTTGGATTTGATTCCTATCCTCTCGC
AGGTATTTAATCGCTTTCGCTGTCGCTACTGCAAGATTCGTTATCCATTCTGGTATGCCCTCTTTGAACTCGGCTTAGGA
ATCCTCTTTCTAGCTTGGTCTTGGGGATGGATTTCCTTGGGTCAAATCATCCTCATCACTGCTGGCCTGACCTTAGGAAT
CTATGACTTTCGCCATCAGGAATATCCCTTGCTGGTCTGGATGACTTTCCACCTAATCCTCATGGCTTTCTGTGGTTGGA
ATCTAGTCATGGTCTTCTTCATTATCCTTGGAATCATGGCTCATTTCATAGATATCCGCATGGGTGCAGGGGATTTTCTC
TTTCTGGCTTCTTGTGCGCTCGTCTTTAGCGTGACAGAATTACTCATCTTGATTCAGTTCGCTTCTGCGGCAGGCATTCT
GGCCTTTCTCCTGCAAAAGAAAAAGGAAAGACTTCCTTTCGTGCCTTTCCTCTTACTTGCTGCAACTATAATAATTTTCT
ATCAGTTCTTATTAGTTTGTTGA

Domains

Predicted by InterproScan.

Bacterial Peptidase A24 N-terminal domain (A24_N_bact)

(8-88)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1X1HZ74

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cclA/cilC Streptococcus mitis SK321

88.128

99.545

0.877
  cclA/cilC Streptococcus pneumoniae Rx1

88.128

99.545

0.877
  cclA/cilC Streptococcus pneumoniae D39

88.128

99.545

0.877
  cclA/cilC Streptococcus pneumoniae R6

88.128

99.545

0.877
  cclA/cilC Streptococcus mitis NCTC 12261

87.671

99.545

0.873
  cclA/cilC Streptococcus pneumoniae TIGR4

87.215

99.545

0.868

Multiple sequence alignment