Detailed information    

insolico Bioinformatically predicted

Overview

Name   comD/comD2   Type   Regulator
Locus tag   DEH83_RS04460 Genome accession   NZ_CP029207
Coordinates   878253..879578 (+) Length   441 a.a.
NCBI ID   WP_304675344.1    Uniprot ID   -
Organism   Streptococcus constellatus strain TCV107     
Function   phosphorylation of ComE (predicted from homology)   
Competence regulation

Genomic Context

Location: 873253..884578
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DEH83_RS04430 (DEH83_04415) dnaA 873539..874882 (-) 1344 WP_006270358.1 chromosomal replication initiator protein DnaA -
  DEH83_RS04435 (DEH83_04420) spo0J 875111..875878 (-) 768 WP_003071657.1 ParB/RepB/Spo0J family partition protein Regulator
  DEH83_RS04440 (DEH83_04425) htrA 875933..877123 (-) 1191 WP_006270334.1 S1C family serine protease Regulator
  DEH83_RS04445 (DEH83_04430) rlmH 877328..877807 (+) 480 WP_255777177.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  DEH83_RS04455 (DEH83_04440) - 878090..878236 (+) 147 WP_006270349.1 ComC/BlpC family leader-containing pheromone/bacteriocin -
  DEH83_RS04460 (DEH83_04445) comD/comD2 878253..879578 (+) 1326 WP_304675344.1 sensor histidine kinase Regulator
  DEH83_RS04465 (DEH83_04450) comE 879578..880327 (+) 750 WP_003071650.1 competence system response regulator transcription factor ComE Regulator
  DEH83_RS04480 (DEH83_04465) - 880646..883225 (-) 2580 WP_255777179.1 YfhO family protein -

Sequence

Protein


Download         Length: 441 a.a.        Molecular weight: 52002.82 Da        Isoelectric Point: 8.4767

>NTDB_id=291180 DEH83_RS04460 WP_304675344.1 878253..879578(+) (comD/comD2) [Streptococcus constellatus strain TCV107]
MVKIEFIHWIIFSIIEAVSVVYCYKKISRVNKVNIHFTLLCLGIVFLTDFTTIIHYSVRYIMFFIQPLFFYLYFVKVKKV
KKHSSLFLALFLSLAVSGSETFFSVIISSVTGDEFVDRYWGLFYIFINIISLIFILKTIDYFKFNFKYFKKVDFKDKIVQ
LNFYLLFIHFLLNVSHWLSNMKSLNSFSSMIATICFLMFMSILFYLQSIREKYEKEEQIKQKEREQLQLQKYTDEIVSLY
NEIRGFRHDYGGMLASFQSAIHTGDIKEVERIYQEVLVNANLQLRSDKYTYFDLNNIGDSALRSVMIQTLFKARDYNIEL
TFEVKDFVKPLPIKLLDLVRMTSVLLNNAIEGSAESYQKTMNVSLVDLDTETILVIQNSRKKRQLDLEMIYQTDFSTKGE
GRGLGLSNIKEIINNYEGIILDTNIEDEYFTQVMRVRKEGL

Nucleotide


Download         Length: 1326 bp        

>NTDB_id=291180 DEH83_RS04460 WP_304675344.1 878253..879578(+) (comD/comD2) [Streptococcus constellatus strain TCV107]
ATAGTGAAAATAGAATTTATACATTGGATTATATTCTCAATTATAGAAGCTGTTTCTGTTGTATATTGTTATAAGAAGAT
AAGTAGAGTGAATAAAGTGAATATTCACTTTACTTTATTATGTTTAGGAATTGTATTTTTGACTGATTTTACTACAATAA
TACATTATTCGGTTAGATATATAATGTTTTTTATTCAACCATTATTTTTTTATTTATACTTTGTTAAAGTAAAAAAAGTT
AAAAAACATTCGTCTTTATTTTTAGCACTATTTTTATCTTTAGCTGTATCAGGTTCTGAAACCTTCTTTTCAGTCATTAT
TTCTTCTGTCACAGGTGATGAGTTTGTTGATAGATACTGGGGATTGTTCTATATTTTTATCAATATTATTTCTTTAATTT
TTATTTTAAAAACTATTGATTATTTTAAGTTTAATTTTAAATATTTTAAAAAGGTTGATTTCAAAGATAAGATTGTACAG
TTAAATTTTTATCTATTATTCATTCATTTTTTATTAAATGTATCGCATTGGCTTAGCAATATGAAAAGTTTAAATAGTTT
TTCTAGTATGATTGCGACGATTTGCTTTTTGATGTTTATGTCAATTTTATTCTACTTACAATCTATTCGTGAAAAATATG
AAAAAGAGGAGCAAATTAAACAAAAAGAACGAGAACAGCTACAACTACAAAAGTATACAGATGAAATTGTGAGTCTTTAC
AATGAAATTCGAGGTTTTCGTCACGATTATGGTGGGATGTTGGCAAGTTTCCAATCTGCCATTCATACAGGTGATATAAA
AGAAGTGGAGCGAATCTATCAGGAGGTTCTCGTAAATGCTAATTTACAGCTTCGTTCTGATAAATATACGTATTTTGATT
TAAATAACATTGGGGATTCAGCACTTAGAAGCGTTATGATACAAACCTTGTTTAAGGCACGTGATTATAATATAGAATTA
ACATTTGAAGTAAAAGATTTTGTCAAGCCTTTGCCGATTAAATTATTAGATCTAGTTAGAATGACAAGTGTTCTTTTAAA
TAATGCAATAGAAGGATCGGCAGAAAGTTATCAAAAAACAATGAATGTTTCTTTGGTAGATTTGGATACAGAAACTATCT
TAGTCATTCAAAATTCACGTAAAAAAAGACAACTAGACTTAGAAATGATTTATCAAACCGATTTTTCAACAAAGGGCGAG
GGACGAGGTTTAGGTTTAAGCAATATCAAAGAAATTATTAATAACTATGAAGGAATTATTCTTGATACAAACATTGAGGA
TGAATATTTTACACAAGTAATGAGAGTAAGGAAAGAAGGTCTATAA

Domains

Predicted by InterproScan.

GHKL domain (HATPase_c_5)

(334-433)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comD/comD2 Streptococcus gordonii strain NCTC7865

54.072

100

0.542
  comD/comD1 Streptococcus gordonii str. Challis substr. CH1

54.338

99.32

0.54
  comD Streptococcus mitis SK321

47.449

88.889

0.422
  comD/comD2 Streptococcus pneumoniae TIGR4

48.67

85.261

0.415
  comD Streptococcus mitis NCTC 12261

48.404

85.261

0.413
  comD/comD1 Streptococcus pneumoniae Rx1

48.138

85.261

0.41
  comD/comD1 Streptococcus pneumoniae D39

48.138

85.261

0.41
  comD/comD1 Streptococcus pneumoniae R6

48.138

85.261

0.41

Multiple sequence alignment