Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   DEH83_RS02345 Genome accession   NZ_CP029207
Coordinates   483530..484285 (-) Length   251 a.a.
NCBI ID   WP_255776964.1    Uniprot ID   -
Organism   Streptococcus constellatus strain TCV107     
Function   degradation of ComW (predicted from homology)   
Competence regulation

Genomic Context

Location: 478530..489285
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DEH83_RS02325 (DEH83_02305) - 478961..480193 (-) 1233 WP_037597770.1 cysteine desulfurase -
  DEH83_RS02330 (DEH83_02310) sufD 480202..481470 (-) 1269 WP_049476980.1 Fe-S cluster assembly protein SufD -
  DEH83_RS02335 (DEH83_02315) sufC 481510..482280 (-) 771 WP_003070295.1 Fe-S cluster assembly ATPase SufC -
  DEH83_RS02340 (DEH83_02320) - 482373..483539 (-) 1167 WP_022524656.1 glycosyltransferase family 4 protein -
  DEH83_RS02345 (DEH83_02325) mecA 483530..484285 (-) 756 WP_255776964.1 adaptor protein MecA Regulator
  DEH83_RS02350 (DEH83_02330) - 484409..485251 (-) 843 WP_255776965.1 undecaprenyl-diphosphate phosphatase -
  DEH83_RS02355 (DEH83_02335) - 485318..487207 (-) 1890 WP_255776966.1 DUF2207 domain-containing protein -
  DEH83_RS02360 (DEH83_02340) - 487335..488900 (+) 1566 WP_049482248.1 ABC transporter substrate-binding protein/permease -

Sequence

Protein


Download         Length: 251 a.a.        Molecular weight: 28983.74 Da        Isoelectric Point: 4.1672

>NTDB_id=291167 DEH83_RS02345 WP_255776964.1 483530..484285(-) (mecA) [Streptococcus constellatus strain TCV107]
MEMKQISDTTIKITIKLEDLEERGMEMADFLVPQEKTEEFFYAILDELEMPESFLDSGMLSFRVTPKPDRLDVFVTKSKI
DKNLNFDDLADLPDVEELSQMSPDEFLKTLEKNIFEKSKDDIEAVRSLETAEAENNTSTSDIEDQEENSDDLTQKYIYYI
LKFSSLKEAIVFSKTVDYAVNTSELYKMDGYYYLTILVDIEGHPKRYPAWLLASMREHAKDTDVTRAVLQEHGYLLLVNE
AVASLQKVKCS

Nucleotide


Download         Length: 756 bp        

>NTDB_id=291167 DEH83_RS02345 WP_255776964.1 483530..484285(-) (mecA) [Streptococcus constellatus strain TCV107]
ATGGAAATGAAGCAAATCAGTGATACAACGATTAAGATCACAATAAAATTAGAAGATTTAGAAGAACGTGGAATGGAGAT
GGCAGATTTTCTTGTTCCGCAAGAAAAGACAGAAGAGTTTTTCTATGCAATTTTAGATGAGTTGGAAATGCCAGAGAGTT
TTTTGGATAGCGGTATGCTCAGTTTTCGTGTAACTCCTAAACCAGACCGACTGGATGTTTTTGTCACCAAGTCTAAGATT
GATAAGAATCTGAACTTTGATGATTTGGCAGATTTACCAGATGTAGAAGAGCTGTCTCAAATGTCTCCAGATGAATTTTT
AAAGACATTAGAAAAAAATATTTTTGAGAAAAGCAAAGACGATATTGAAGCTGTTCGGTCTTTGGAAACGGCAGAAGCAG
AAAATAATACGAGCACTTCTGACATAGAAGATCAAGAAGAAAATAGTGACGACCTTACTCAAAAATATATCTATTATATC
TTGAAATTTTCCAGCTTGAAAGAAGCGATTGTCTTTTCTAAAACAGTAGACTATGCTGTTAACACTTCGGAGTTGTACAA
AATGGATGGTTACTATTATTTAACAATCTTGGTTGATATTGAAGGACATCCTAAGCGTTATCCAGCTTGGCTTTTGGCTT
CTATGCGTGAACATGCAAAAGACACAGATGTGACAAGAGCTGTTTTGCAAGAGCATGGTTATTTACTGCTTGTCAACGAG
GCGGTTGCTAGTCTTCAAAAGGTTAAATGCTCATGA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-245)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus pneumoniae Rx1

66.532

98.805

0.657
  mecA Streptococcus pneumoniae D39

66.532

98.805

0.657
  mecA Streptococcus pneumoniae R6

66.532

98.805

0.657
  mecA Streptococcus pneumoniae TIGR4

66.129

98.805

0.653
  mecA Streptococcus mutans UA159

50

98.805

0.494
  mecA Streptococcus thermophilus LMD-9

46.094

100

0.47
  mecA Streptococcus thermophilus LMG 18311

45.703

100

0.466

Multiple sequence alignment