Detailed information    

insolico Bioinformatically predicted

Overview

Name   stkP   Type   Regulator
Locus tag   DEH83_RS02180 Genome accession   NZ_CP029207
Coordinates   446965..448848 (-) Length   627 a.a.
NCBI ID   WP_255776951.1    Uniprot ID   -
Organism   Streptococcus constellatus strain TCV107     
Function   require for competence development; phosphorylate ComE (predicted from homology)   
Competence regulation

Genomic Context

Location: 441965..453848
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DEH83_RS02150 (DEH83_02130) - 442106..442426 (+) 321 WP_255776950.1 DUF960 domain-containing protein -
  DEH83_RS02155 (DEH83_02135) - 442543..442935 (-) 393 WP_020997633.1 S1 RNA-binding domain-containing protein -
  DEH83_RS02160 (DEH83_02140) - 442937..444337 (-) 1401 WP_070484181.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  DEH83_RS02165 (DEH83_02145) - 444384..445016 (-) 633 WP_003070225.1 response regulator transcription factor -
  DEH83_RS02170 (DEH83_02150) - 445018..446014 (-) 997 Protein_431 sensor histidine kinase -
  DEH83_RS02175 (DEH83_02155) liaF 446011..446709 (-) 699 WP_003070232.1 cell wall-active antibiotics response protein LiaF -
  DEH83_RS02180 (DEH83_02160) stkP 446965..448848 (-) 1884 WP_255776951.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  DEH83_RS02185 (DEH83_02165) - 448845..449585 (-) 741 WP_003028411.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  DEH83_RS02190 (DEH83_02170) rsmB 449604..450917 (-) 1314 WP_255776952.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  DEH83_RS02195 (DEH83_02175) fmt 450907..451842 (-) 936 WP_255776953.1 methionyl-tRNA formyltransferase -

Sequence

Protein


Download         Length: 627 a.a.        Molecular weight: 68007.22 Da        Isoelectric Point: 9.5726

>NTDB_id=291165 DEH83_RS02180 WP_255776951.1 446965..448848(-) (stkP) [Streptococcus constellatus strain TCV107]
MIQVGKIFAGRYRIIKQIGRGGMADVYLAKDLILDGEEVAVKVLRTNYQTDPIAVARFQREARAMADLDHPHIVRITDIG
EEEGQQYLAMEYVAGLDLKRYIKEHAPLSNEEAVRIMGQILLAMRLAHTHGIVHRDLKPQNVLLTPDGDAKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATVQSDIYAMGIIFYEMLTGHIPYDGDSAVTIALQHFQKPLPSVIAENPNVP
QPLENVVIKATAKKLTDRYQSVAEMYVDLSSCLSADRRNEKKLVFDDTAKADTKTLPKVSQNTLISASKPTTPTPIKETV
SSNSQPTTKPKTKKKRRLRTRYKVLLSAVVLVIAALVALVYLSPSNVKIPDVTGKTVAQARSAIETAGLKVGKEKDEYSD
SVKKDSVIRTNPEAGTQRRDGSTVDLIVSKGTKTFIMEDYKGQKRADAINNLVQKYKVSKGLIKTEEVESSEHAAGTVVG
QTPAAGSTYDLTSKARITLKVAKSVSSVVMPSYIGSTYEFAYNNLTQVLGIQGANIEKRTVPTAPAGTQANTIIKQTPAA
NQSLDLKSDRIVLYVYEPKTESSSTSESSLQSESSSEKNSPSSSNSSTSGNDGSSSKTPDTSASASN

Nucleotide


Download         Length: 1884 bp        

>NTDB_id=291165 DEH83_RS02180 WP_255776951.1 446965..448848(-) (stkP) [Streptococcus constellatus strain TCV107]
ATGATTCAAGTCGGCAAGATATTTGCCGGGCGATATAGAATCATCAAACAAATTGGGCGAGGTGGCATGGCAGATGTTTA
CTTGGCCAAAGATTTGATTTTAGACGGGGAAGAAGTCGCGGTGAAAGTTCTAAGAACGAATTACCAGACGGATCCGATTG
CTGTGGCGCGCTTTCAAAGAGAGGCGCGAGCGATGGCAGACTTGGATCATCCTCATATTGTCCGGATTACCGATATTGGA
GAAGAAGAAGGTCAGCAATATCTAGCAATGGAATATGTGGCTGGGCTTGACTTAAAACGCTATATTAAAGAGCATGCTCC
TTTATCTAATGAAGAAGCGGTTCGGATTATGGGACAAATTCTTTTGGCGATGCGTTTGGCGCATACGCATGGAATTGTTC
ATCGTGATTTGAAGCCACAAAATGTCCTTTTAACTCCAGATGGCGATGCAAAAGTAACGGACTTTGGAATTGCAGTAGCT
TTTGCAGAAACGAGTTTAACCCAGACAAATTCAATGCTGGGATCTGTGCATTATCTATCACCAGAACAAGCGCGTGGTTC
AAAAGCGACCGTTCAAAGCGATATTTATGCTATGGGGATCATTTTCTATGAAATGTTGACAGGACATATCCCTTATGATG
GGGATAGTGCTGTCACAATTGCTTTGCAACATTTCCAAAAGCCTCTTCCTTCTGTGATTGCTGAAAATCCAAATGTGCCA
CAGCCTCTAGAAAATGTAGTCATCAAGGCAACGGCTAAAAAATTAACAGATCGTTATCAATCTGTTGCAGAAATGTATGT
GGATTTATCAAGCTGCTTATCCGCAGATCGCCGAAATGAGAAAAAGTTGGTTTTTGATGATACTGCCAAAGCAGATACCA
AGACGCTTCCTAAAGTGTCACAAAATACCTTAATTTCTGCAAGCAAACCAACTACTCCTACGCCTATAAAAGAAACAGTC
AGTAGTAATTCTCAACCCACAACCAAGCCAAAAACAAAGAAAAAGCGTCGTTTAAGAACGCGTTATAAGGTTCTGTTGTC
GGCAGTAGTTTTAGTGATTGCTGCTCTGGTGGCATTAGTCTATTTGAGTCCGTCAAATGTAAAAATTCCAGACGTTACTG
GAAAAACTGTTGCACAGGCTCGTTCTGCAATTGAAACAGCAGGTTTGAAAGTTGGTAAGGAAAAAGATGAATATAGCGAC
TCTGTCAAAAAGGATTCTGTTATTCGCACCAATCCAGAAGCGGGAACACAGCGTCGCGACGGAAGCACGGTGGATCTGAT
TGTTTCCAAAGGTACAAAAACCTTTATTATGGAAGATTATAAAGGTCAGAAAAGAGCGGATGCTATCAACAATCTAGTCC
AAAAATACAAGGTTTCAAAAGGTTTAATTAAAACAGAAGAAGTTGAAAGTAGTGAGCATGCGGCTGGAACAGTCGTTGGT
CAAACGCCAGCAGCAGGTAGTACATATGATTTGACTTCAAAAGCTCGTATTACTTTGAAAGTAGCCAAGTCCGTTTCAAG
TGTTGTTATGCCAAGTTATATCGGTTCAACCTATGAATTTGCCTATAACAATTTAACGCAAGTGCTTGGCATTCAAGGTG
CTAATATTGAAAAACGAACGGTTCCAACAGCTCCGGCGGGAACACAAGCAAATACGATTATTAAACAAACGCCAGCAGCA
AATCAGTCCTTGGATTTGAAGAGCGACCGCATTGTCCTATATGTATATGAGCCGAAAACCGAAAGTTCGTCTACATCTGA
AAGTAGTTTGCAATCTGAAAGTAGTTCAGAAAAAAATAGTCCATCGTCTAGTAACTCATCAACTAGTGGTAATGATGGTT
CAAGTTCAAAAACGCCAGACACAAGTGCTAGTGCAAGCAATTAA

Domains

Predicted by InterproScan.

Protein kinase domain (Pkinase)

(12-227)

PASTA domain (PASTA)

(508-576)

PASTA domain (PASTA)

(436-503)

PASTA domain (PASTA)

(367-430)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  stkP Streptococcus pneumoniae TIGR4

65.588

93.62

0.614
  stkP Streptococcus pneumoniae D39

65.247

93.62

0.611
  stkP Streptococcus pneumoniae R6

65.247

93.62

0.611
  stkP Streptococcus pneumoniae Rx1

65.077

93.62

0.609
  pknB Streptococcus mutans UA159

58.803

93.301

0.549
  stkP/pknB Streptococcus salivarius strain HSISS4

55.184

95.375

0.526

Multiple sequence alignment