Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilR   Type   Regulator
Locus tag   PSPA7_RS24735 Genome accession   NC_009656
Coordinates   5333784..5335121 (+) Length   445 a.a.
NCBI ID   WP_012077306.1    Uniprot ID   A6VBT4
Organism   Pseudomonas paraeruginosa PA7     
Function   regulate pilin expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 5328784..5340121
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PSPA7_RS24710 (PSPA7_5182) pgeF 5328929..5329657 (-) 729 WP_012077304.1 peptidoglycan editing factor PgeF -
  PSPA7_RS24715 (PSPA7_5183) rluD 5329654..5330616 (-) 963 WP_003150035.1 23S rRNA pseudouridine(1911/1915/1917) synthase RluD -
  PSPA7_RS24720 (PSPA7_5184) - 5330762..5331787 (+) 1026 WP_012077305.1 outer membrane protein assembly factor BamD -
  PSPA7_RS24725 (PSPA7_5185) - 5331941..5332186 (+) 246 WP_003150030.1 PP0621 family protein -
  PSPA7_RS24730 (PSPA7_5186) pilS 5332176..5333768 (+) 1593 WP_003150028.1 two-component system sensor histidine kinase PilS Regulator
  PSPA7_RS24735 (PSPA7_5187) pilR 5333784..5335121 (+) 1338 WP_012077306.1 two-component system response regulator PilR Regulator
  PSPA7_RS24740 (PSPA7_5188) thiO 5335167..5336261 (-) 1095 WP_041025522.1 glycine oxidase ThiO -
  PSPA7_RS24745 (PSPA7_5189) - 5336396..5336905 (+) 510 WP_003150026.1 GspH/FimT family protein -
  PSPA7_RS24750 (PSPA7_5190) - 5337011..5337517 (+) 507 WP_012077308.1 Tfp pilus assembly protein FimT/FimU -
  PSPA7_RS24755 (PSPA7_5191) pilV 5337508..5338065 (+) 558 WP_012077309.1 type IV pilus modification protein PilV Machinery gene
  PSPA7_RS24760 (PSPA7_5192) pilW 5338062..5338886 (+) 825 WP_012077310.1 type 4a pilus minor pilin PilW -
  PSPA7_RS24765 (PSPA7_5193) pilX 5338883..5339470 (+) 588 WP_003150019.1 type 4a pilus minor pilin PilX -

Sequence

Protein


Download         Length: 445 a.a.        Molecular weight: 49801.15 Da        Isoelectric Point: 6.2877

>NTDB_id=28556 PSPA7_RS24735 WP_012077306.1 5333784..5335121(+) (pilR) [Pseudomonas paraeruginosa PA7]
MSRQKALIVDDEPDIRELLEITLGRMKLDTRSARNVKEARELLAREPFDLCLTDMRLPDGSGLDLVQYIQQRHPQTPVAM
ITAYGSLDTAIQALKAGAFDFLTKPVDLGRLRELVATALRLRHPETEEAPVDNRLLGESPPMRALRNQIGKLARSQAPVY
ISGESGSGKELVARLIHEQGPRIERPFVPVNCGAIPTELMESEFFGHKKGSFTGAIEDKQGLFQAASGGTLFLDEVADLP
MPMQVKLLRAIQEKAVRAVGGQQEIGVDVRILCATHKDLAAEVGAGRFRQDLYYRLNVIELRVPPLRERREDIPLLAERI
LKRLAGDTGLPAARLTGDAQEKLKNYRFPGNVRELENMLERAYTLCENDQIQPHDLRVADAPGASQDGAASLSEIDNLED
YLEDIERKLIMQALEETRWNRTAAAQRLGLTFRSMRYRLKKLGID

Nucleotide


Download         Length: 1338 bp        

>NTDB_id=28556 PSPA7_RS24735 WP_012077306.1 5333784..5335121(+) (pilR) [Pseudomonas paraeruginosa PA7]
ATGAGCCGACAAAAAGCCCTGATCGTCGACGATGAACCGGATATCCGCGAGCTGCTGGAAATCACCCTCGGCCGCATGAA
GCTGGATACCCGCAGCGCCCGCAACGTCAAGGAAGCCCGCGAGTTGCTGGCCCGCGAACCGTTCGACCTGTGCCTGACCG
ACATGCGCCTGCCGGACGGTAGCGGCCTCGACCTGGTGCAGTACATCCAGCAGCGTCACCCGCAAACTCCGGTCGCCATG
ATCACCGCCTACGGCAGCCTGGACACCGCGATCCAGGCGCTCAAGGCCGGCGCCTTCGACTTCCTCACCAAGCCGGTCGA
CCTCGGCCGCCTGCGCGAACTGGTGGCGACCGCCCTGCGCCTGCGCCATCCGGAAACCGAGGAAGCGCCGGTGGACAACC
GCCTGCTCGGCGAGTCTCCGCCGATGCGCGCGCTGCGCAACCAGATCGGCAAGCTGGCGCGCAGCCAGGCGCCGGTCTAC
ATCAGCGGCGAGTCCGGCAGCGGCAAGGAACTGGTGGCCCGCCTGATCCACGAGCAGGGGCCGCGCATCGAGCGACCGTT
CGTGCCGGTCAACTGCGGCGCGATCCCTACCGAGCTGATGGAAAGCGAGTTCTTCGGCCACAAGAAAGGCAGCTTCACCG
GCGCCATCGAGGACAAGCAGGGCCTGTTCCAGGCCGCCAGCGGCGGTACCCTGTTCCTCGACGAAGTCGCCGACCTGCCG
ATGCCGATGCAGGTCAAGCTGCTCCGCGCAATCCAGGAAAAGGCCGTGCGCGCGGTCGGCGGCCAGCAGGAGATCGGCGT
CGACGTCCGCATCCTCTGCGCCACCCACAAGGACCTCGCCGCCGAGGTCGGCGCCGGGCGCTTCCGCCAGGATCTCTACT
ACCGCCTCAACGTCATCGAATTGCGCGTTCCGCCCCTGCGCGAACGCCGCGAGGACATCCCGCTGCTGGCCGAGCGCATC
CTCAAGCGCCTGGCCGGCGATACCGGCTTGCCAGCCGCCCGCCTGACCGGCGATGCCCAGGAAAAGCTGAAGAACTATCG
CTTCCCCGGCAACGTGCGTGAACTGGAGAACATGCTGGAGCGCGCCTACACGCTGTGCGAGAACGACCAGATCCAGCCCC
ACGACCTGCGCGTGGCCGACGCGCCGGGCGCCAGCCAGGACGGCGCGGCGAGCCTGAGCGAGATAGACAATCTCGAGGAC
TACCTGGAAGACATCGAGCGCAAGCTGATCATGCAGGCTCTCGAGGAGACCCGCTGGAACCGCACTGCCGCGGCCCAGCG
CCTGGGCCTGACGTTCCGTTCGATGCGTTATCGCCTGAAGAAACTCGGCATAGATTGA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(7-115)

Sigma-54 interaction domain (Sigma54_activat)

(135-301)

Bacterial regulatory protein, Fis family (HTH_8)

(402-442)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A6VBT4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilR Pseudomonas aeruginosa PAK

97.978

100

0.98
  pilR Acinetobacter baumannii strain A118

51.416

100

0.53
  luxO Vibrio cholerae strain A1552

38.063

99.775

0.38

Multiple sequence alignment