Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   SK637_RS09525 Genome accession   NZ_CP028415
Coordinates   1909963..1911261 (-) Length   432 a.a.
NCBI ID   WP_033689573.1    Uniprot ID   -
Organism   Streptococcus mitis strain SK637     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1904963..1916261
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SK637_RS09505 (SK637_01853) rplI 1906118..1906570 (-) 453 WP_000864214.1 50S ribosomal protein L9 -
  SK637_RS09510 (SK637_01854) - 1906567..1908540 (-) 1974 WP_033689571.1 DHH family phosphoesterase -
  SK637_RS09515 (SK637_01855) hpf 1908676..1909224 (-) 549 WP_000599100.1 ribosome hibernation-promoting factor, HPF/YfiA family -
  SK637_RS09520 (SK637_01856) comFC/cflB 1909304..1909966 (-) 663 WP_033689572.1 ComF family protein Machinery gene
  SK637_RS09525 (SK637_01857) comFA/cflA 1909963..1911261 (-) 1299 WP_033689573.1 DEAD/DEAH box helicase Machinery gene
  SK637_RS09530 (SK637_01858) - 1911318..1911953 (+) 636 WP_033689575.1 YigZ family protein -
  SK637_RS10210 - 1912047..1912142 (+) 96 Protein_1786 PH domain-containing protein -
  SK637_RS09540 (SK637_01859) cysK 1912239..1913165 (+) 927 WP_000029885.1 cysteine synthase A -
  SK637_RS09545 (SK637_01860) tsf 1913286..1914326 (-) 1041 WP_033689577.1 translation elongation factor Ts -
  SK637_RS09550 (SK637_01861) rpsB 1914405..1915184 (-) 780 WP_000268459.1 30S ribosomal protein S2 -

Sequence

Protein


Download         Length: 432 a.a.        Molecular weight: 49512.48 Da        Isoelectric Point: 8.6688

>NTDB_id=284740 SK637_RS09525 WP_033689573.1 1909963..1911261(-) (comFA/cflA) [Streptococcus mitis strain SK637]
MKVNPNYLGRLFTENELTKEEHQLAEKLPAMRKEKGKLFCQRCDSAILDEWYLPIGAYYCRECLLMKRVRSDQALYYFPQ
EDFSKQDVLKWRGQLTPFQEKVSEGLIQAVDKQEPTLVHAVTGAGKTEMIYQVVAKVINRGGAVCLASPRIDVCLELYKR
LQQDFACKISLLHGESEPYFRTPLVVATTHQLLKFYQAFDLLIVDEVDAFPYVDNPTLYHAVKNSVKENGLRIFLTATST
DELDRKVRIGELKLLSLPRRFHGNPLIIPKPVWLSDFNHCLEKSRLSPKLKSYIEKQRKTAYPLLIFASEIKKGEQLKEI
LQEQFPHEKIGFVSSITEDRLEQVQAFRDGKLTILISTTILERGVTFPCVDVFVVEANHRLFTKSSLIQIGGRVGRSMDR
PTGDLLFFHDGLNASIKKAIKEIQQMNKEAGL

Nucleotide


Download         Length: 1299 bp        

>NTDB_id=284740 SK637_RS09525 WP_033689573.1 1909963..1911261(-) (comFA/cflA) [Streptococcus mitis strain SK637]
ATGAAAGTAAATCCAAATTATCTCGGTCGTTTGTTTACTGAGAATGAATTAACTAAAGAGGAACATCAGTTGGCGGAGAA
ACTTCCAGCAATGAGAAAGGAGAAAGGGAAACTTTTCTGTCAACGTTGTGATAGTGCTATTTTAGATGAATGGTATTTGC
CCATCGGTGCTTACTATTGTAGGGAGTGTTTACTGATGAAGCGAGTCAGGAGTGATCAAGCTTTATACTATTTTCCGCAG
GAGGATTTTTCGAAACAAGATGTTCTTAAATGGCGTGGTCAATTAACTCCTTTTCAAGAGAAGGTATCAGAGGGACTGAT
TCAAGCAGTAGACAAGCAAGAGCCAACTTTAGTTCATGCGGTGACAGGGGCTGGAAAGACAGAAATGATTTATCAAGTTG
TGGCTAAGGTGATTAATAGGGGTGGTGCAGTTTGTTTGGCTAGTCCTCGCATAGATGTTTGTTTGGAGCTGTACAAGCGC
CTGCAACAGGATTTTGCTTGCAAGATATCTTTACTACACGGAGAATCAGAGCCGTATTTTCGAACACCACTAGTTGTTGC
GACGACCCATCAGTTATTGAAGTTTTATCAAGCTTTTGATTTGCTGATAGTGGATGAAGTAGATGCCTTTCCTTATGTTG
ACAATCCCACGCTTTACCATGCTGTCAAGAATAGTGTAAAGGAGAATGGCTTGAGAATCTTTTTAACAGCGACTTCTACC
GATGAGTTAGATAGGAAGGTTCGCATCGGAGAATTAAAACTATTGAGTTTGCCAAGACGATTTCATGGAAATCCTTTGAT
TATTCCTAAACCTGTCTGGTTATCCGATTTTAATCACTGTTTAGAGAAAAGTCGGTTGTCACCAAAGCTAAAGTCTTATA
TTGAGAAGCAGAGAAAGACAGCTTATCCATTACTCATTTTTGCTTCAGAAATTAAGAAAGGGGAGCAGTTAAAAGAAATC
TTACAGGAGCAATTTCCGCATGAGAAAATTGGCTTTGTATCTTCTATCACAGAAGATCGATTAGAGCAGGTACAAGCTTT
TAGAGATGGAAAATTGACAATACTTATCAGTACGACGATATTGGAGCGCGGAGTTACTTTCCCTTGTGTGGATGTTTTCG
TAGTAGAGGCCAATCATCGCCTTTTTACCAAGTCTAGCTTGATTCAGATTGGTGGACGAGTTGGACGAAGCATGGATAGA
CCAACAGGAGATTTGCTTTTTTTCCATGATGGGTTAAATGCTTCAATCAAGAAGGCAATTAAGGAAATTCAGCAGATGAA
TAAGGAGGCGGGGCTATGA

Domains

Predicted by InterproScan.

Helicase conserved C-terminal domain (Helicase_C)

(293-396)

Type III restriction enzyme, res subunit (ResIII)

(94-238)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus mitis SK321

94.907

100

0.949
  comFA/cflA Streptococcus mitis NCTC 12261

94.213

100

0.942
  comFA/cflA Streptococcus pneumoniae Rx1

92.824

100

0.928
  comFA/cflA Streptococcus pneumoniae D39

92.824

100

0.928
  comFA/cflA Streptococcus pneumoniae R6

92.824

100

0.928
  comFA/cflA Streptococcus pneumoniae TIGR4

92.593

100

0.926
  comFA Lactococcus lactis subsp. cremoris KW2

49.883

99.306

0.495
  comFA Latilactobacillus sakei subsp. sakei 23K

38.799

100

0.389
  comFA Bacillus subtilis subsp. subtilis str. 168

38.821

94.213

0.366

Multiple sequence alignment