Detailed information    

insolico Bioinformatically predicted

Overview

Name   stkP   Type   Regulator
Locus tag   SK637_RS07530 Genome accession   NZ_CP028415
Coordinates   1497304..1499205 (-) Length   633 a.a.
NCBI ID   WP_033689221.1    Uniprot ID   -
Organism   Streptococcus mitis strain SK637     
Function   require for competence development; phosphorylate ComE (predicted from homology)   
Competence regulation

Genomic Context

Location: 1492304..1504205
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SK637_RS07510 (SK637_01462) - 1493441..1494715 (-) 1275 WP_033689217.1 hydroxymethylglutaryl-CoA reductase, degradative -
  SK637_RS07515 (SK637_01463) - 1494715..1495887 (-) 1173 WP_033689651.1 hydroxymethylglutaryl-CoA synthase -
  SK637_RS07520 (SK637_01464) - 1496000..1496449 (-) 450 WP_033689218.1 threonine/serine exporter family protein -
  SK637_RS07525 (SK637_01465) - 1496451..1497209 (-) 759 WP_033689220.1 threonine/serine exporter family protein -
  SK637_RS07530 (SK637_01466) stkP 1497304..1499205 (-) 1902 WP_033689221.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  SK637_RS07535 (SK637_01467) - 1499202..1499942 (-) 741 WP_033685450.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  SK637_RS07540 rsmB 1499957..1501269 (-) 1313 Protein_1398 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  SK637_RS07545 (SK637_01470) fmt 1501262..1502197 (-) 936 WP_033689222.1 methionyl-tRNA formyltransferase -

Sequence

Protein


Download         Length: 633 a.a.        Molecular weight: 69402.86 Da        Isoelectric Point: 9.2775

>NTDB_id=284721 SK637_RS07530 WP_033689221.1 1497304..1499205(-) (stkP) [Streptococcus mitis strain SK637]
MIQIGKIFAGRYRIIKQIGRGGMADVYLAKDLILDGEEVAVKVLRTNYQTDPIAVARFQREARAMADLDHPHIVRITDIG
EEEGQQYLAMEYVAGLDLKRYIKEHHPLSNEEAIRIMGQILLAMRLAHTRGIVHRDLKPQNILLTPDGTAKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATVQSDIYAMGIIFYEMLTGHIPYDGDSAVTIALQHFQKPLPSVIAENPSVP
QALENVVIKATAKKLTDRYKSVAEMYVDLSSSLSYNRRNEPKLVFDDATKADTKTLPKVPQSTLTSIPKAPVQEERPQPK
PQPHQTEKTVPSPKPTKRRRMKARYPILFATFLLVVASLVWILYRTPATIAIPNVAGQTVAEAKEALKKANFEVGEEKTE
ASDKVEEGRVIRTDPDAGTTRKEGTKINLIVSSGQQSFQLGNYLGRRSSDVVAELKGKKVPENLIKIEEEESNEIEAGTI
MKQSLPEGTTYDLSKATQIVLTVAKKVNSISMPSYIGSSREFAVNNLTEIYDIKKANIEVVEVSKAPEGTAEGTVVEQSP
KAGEKVDLSTTRVKISIYKAKQTHTSSTSSSSSSSSSSSSSRKPNEPGNAETTPTQGNSQGNSQRGDTSPNNP

Nucleotide


Download         Length: 1902 bp        

>NTDB_id=284721 SK637_RS07530 WP_033689221.1 1497304..1499205(-) (stkP) [Streptococcus mitis strain SK637]
ATGATCCAAATCGGCAAGATTTTTGCCGGGCGGTATCGGATTATCAAACAAATTGGTCGAGGAGGCATGGCAGATGTCTA
TTTGGCCAAGGATTTGATTTTGGACGGTGAAGAAGTGGCAGTGAAGGTCCTGAGGACCAACTACCAGACAGATCCTATTG
CAGTGGCTCGTTTTCAGCGGGAAGCGAGAGCTATGGCAGATCTGGACCATCCTCATATCGTTCGGATTACAGATATCGGT
GAAGAAGAGGGACAACAGTATCTCGCAATGGAATATGTTGCTGGATTAGACCTCAAACGCTATATCAAGGAACATCACCC
TCTTTCAAATGAAGAAGCGATTCGAATCATGGGACAAATCCTCTTGGCTATGCGCTTAGCCCATACTCGAGGAATTGTTC
ACAGGGACTTGAAACCGCAAAATATCCTTTTGACCCCAGATGGGACTGCCAAGGTTACAGACTTTGGGATTGCAGTAGCC
TTTGCAGAGACGAGTCTGACTCAGACCAACTCAATGCTAGGTTCAGTTCATTATTTATCGCCAGAGCAGGCGCGTGGTTC
TAAAGCAACTGTGCAGAGTGATATCTATGCCATGGGGATTATTTTCTATGAGATGCTGACAGGTCATATTCCTTACGATG
GGGATAGTGCAGTGACCATCGCCCTCCAGCATTTCCAGAAACCGCTGCCATCGGTTATAGCTGAAAATCCATCTGTACCT
CAGGCTTTAGAGAATGTTGTTATTAAGGCAACTGCTAAGAAATTAACAGATCGTTACAAATCAGTCGCTGAAATGTATGT
GGATTTGTCTAGTAGTTTGTCTTACAATCGTCGCAATGAACCAAAGTTGGTCTTTGATGATGCAACTAAGGCAGATACTA
AAACTCTTCCTAAAGTTCCACAAAGTACTCTGACTTCTATTCCTAAAGCTCCGGTACAAGAGGAAAGACCTCAACCTAAG
CCCCAACCTCATCAGACAGAAAAAACGGTACCTAGTCCAAAGCCAACCAAACGCCGTCGCATGAAAGCACGTTATCCAAT
TTTATTTGCGACCTTCTTGTTGGTTGTGGCATCCTTGGTATGGATTTTATATAGAACGCCCGCTACCATTGCCATTCCAA
ATGTGGCAGGTCAGACGGTTGCTGAGGCTAAAGAAGCACTTAAGAAAGCCAATTTTGAGGTTGGTGAAGAAAAAACAGAG
GCTAGTGATAAGGTTGAAGAAGGTCGTGTTATTCGTACCGATCCTGACGCTGGTACGACACGCAAAGAAGGAACAAAAAT
TAATTTGATTGTGTCTTCTGGTCAGCAGTCTTTCCAACTCGGAAATTATCTCGGAAGAAGGTCCAGTGATGTAGTGGCAG
AGTTGAAAGGTAAGAAGGTTCCAGAAAATCTGATTAAGATTGAGGAAGAAGAATCCAACGAAATCGAAGCCGGTACAATC
ATGAAACAAAGTTTGCCGGAGGGAACAACCTATGATCTTAGCAAGGCAACTCAAATAGTTTTGACAGTTGCTAAAAAAGT
AAATTCTATTTCAATGCCAAGCTATATTGGTTCTAGTCGAGAATTTGCAGTCAATAATCTTACAGAGATATATGACATTA
AAAAAGCTAATATCGAAGTTGTAGAAGTGTCTAAAGCTCCTGAAGGAACTGCTGAGGGGACTGTTGTAGAGCAAAGTCCA
AAAGCAGGCGAAAAAGTAGACTTGAGCACTACTCGTGTTAAAATTTCTATTTATAAAGCAAAACAAACTCATACTTCTTC
AACATCTTCATCCTCATCTTCTTCTTCGTCGTCTAGTTCTTCTCGGAAACCTAACGAGCCGGGGAATGCAGAAACCACTC
CAACACAAGGAAACTCGCAAGGTAATTCACAACGAGGAGATACTTCCCCAAATAATCCATAA

Domains

Predicted by InterproScan.

Protein kinase domain (Pkinase)

(12-227)

PASTA domain (PASTA)

(511-579)

PASTA domain (PASTA)

(442-505)

PASTA domain (PASTA)

(371-432)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  stkP Streptococcus pneumoniae TIGR4

79.038

91.943

0.727
  stkP Streptococcus pneumoniae D39

78.694

91.943

0.724
  stkP Streptococcus pneumoniae R6

78.694

91.943

0.724
  stkP Streptococcus pneumoniae Rx1

78.522

91.943

0.722
  pknB Streptococcus mutans UA159

55.786

91.469

0.51
  stkP/pknB Streptococcus salivarius strain HSISS4

54.949

92.575

0.509

Multiple sequence alignment