Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGD   Type   Machinery gene
Locus tag   EGX78_RS00815 Genome accession   NZ_CP033767
Coordinates   131547..131975 (+) Length   142 a.a.
NCBI ID   WP_002986548.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain FDAARGOS_534     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 126547..136975
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EGX78_RS00795 (EGX78_00795) - 128878..129243 (+) 366 WP_002986560.1 DUF1033 family protein -
  EGX78_RS00800 (EGX78_00800) comGA 129336..130274 (+) 939 WP_002987773.1 competence type IV pilus ATPase ComGA Machinery gene
  EGX78_RS00805 (EGX78_00805) comGB 130210..131244 (+) 1035 WP_223845212.1 competence type IV pilus assembly protein ComGB Machinery gene
  EGX78_RS00810 (EGX78_00810) comGC 131246..131572 (+) 327 WP_002986552.1 competence type IV pilus major pilin ComGC Machinery gene
  EGX78_RS00815 (EGX78_00815) comGD 131547..131975 (+) 429 WP_002986548.1 competence type IV pilus minor pilin ComGD Machinery gene
  EGX78_RS00820 (EGX78_00820) comGE 131932..132216 (+) 285 WP_002987779.1 competence type IV pilus minor pilin ComGE Machinery gene
  EGX78_RS00825 (EGX78_00825) comGF 132209..132643 (+) 435 WP_002987783.1 competence type IV pilus minor pilin ComGF Machinery gene
  EGX78_RS00830 (EGX78_00830) comGG 132627..132953 (+) 327 WP_002987787.1 competence type IV pilus minor pilin ComGG -
  EGX78_RS00835 (EGX78_00835) comGH 133051..134004 (+) 954 WP_002987790.1 class I SAM-dependent methyltransferase Machinery gene
  EGX78_RS00840 (EGX78_00840) - 134063..135259 (+) 1197 WP_123949427.1 acetate kinase -
  EGX78_RS00845 (EGX78_00845) - 135446..135754 (+) 309 WP_032461811.1 hypothetical protein -
  EGX78_RS00850 (EGX78_00850) proC 135837..136607 (-) 771 WP_002986527.1 pyrroline-5-carboxylate reductase -

Sequence

Protein


Download         Length: 142 a.a.        Molecular weight: 16310.04 Da        Isoelectric Point: 10.3481

>NTDB_id=284494 EGX78_RS00815 WP_002986548.1 131547..131975(+) (comGD) [Streptococcus pyogenes strain FDAARGOS_534]
MKKPVLAIKAFTLLETLLSLSVMSFIILGLSVPVTKSYQKVEEHLFFSHFEHLYRHQQKLAILQQKQRVLDISSTKIVTE
GNSLTVPKSITVNHPYRLVIDQMGGNHSLAKIIFDMTDRRFKYQFYLGSGNYQKTSQSLHSP

Nucleotide


Download         Length: 429 bp        

>NTDB_id=284494 EGX78_RS00815 WP_002986548.1 131547..131975(+) (comGD) [Streptococcus pyogenes strain FDAARGOS_534]
ATGAAAAAGCCCGTCTTAGCAATTAAAGCTTTTACTTTGCTTGAAACTTTACTAAGTTTGTCAGTGATGAGTTTCATTAT
ATTGGGATTGTCTGTACCAGTGACAAAAAGCTATCAAAAAGTAGAAGAGCATCTGTTTTTTAGCCATTTTGAACATTTGT
ATCGACATCAGCAAAAGTTAGCCATATTACAGCAAAAACAGCGCGTCTTGGATATTTCTTCAACAAAAATTGTTACAGAA
GGTAATAGCCTAACAGTTCCTAAATCAATAACAGTGAATCATCCTTATCGGTTAGTTATTGATCAGATGGGAGGCAACCA
TTCCTTAGCTAAAATTATTTTTGACATGACTGATCGACGCTTTAAATACCAATTTTATCTAGGGAGTGGGAATTATCAAA
AAACAAGTCAAAGCTTACATAGCCCTTGA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGD Streptococcus mutans UA159

45.736

90.845

0.415
  comGD Streptococcus mutans UA140

45.736

90.845

0.415
  comGD/cglD Streptococcus mitis NCTC 12261

40.441

95.775

0.387
  comGD Streptococcus gordonii str. Challis substr. CH1

40.458

92.254

0.373
  comGD/cglD Streptococcus mitis SK321

39.695

92.254

0.366
  comGD/cglD Streptococcus pneumoniae Rx1

39.695

92.254

0.366
  comGD/cglD Streptococcus pneumoniae D39

39.695

92.254

0.366
  comGD/cglD Streptococcus pneumoniae R6

39.695

92.254

0.366

Multiple sequence alignment