Detailed information    

insolico Bioinformatically predicted

Overview

Name   recD/recD2/recDB   Type   Machinery gene
Locus tag   EGC57_RS07970 Genome accession   NZ_CP033621
Coordinates   1533365..1535818 (+) Length   817 a.a.
NCBI ID   WP_076639282.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain M75     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1528365..1540818
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EGC57_RS07950 (EGC57_07960) - 1530788..1531333 (-) 546 WP_002983087.1 CvpA family protein -
  EGC57_RS07955 (EGC57_07965) - 1531336..1531644 (-) 309 WP_002993251.1 hypothetical protein -
  EGC57_RS07960 (EGC57_07970) rnhC 1531801..1532703 (+) 903 WP_010922635.1 ribonuclease HIII -
  EGC57_RS07965 (EGC57_07975) lepB 1532714..1533307 (+) 594 WP_030127555.1 signal peptidase I -
  EGC57_RS07970 (EGC57_07980) recD/recD2/recDB 1533365..1535818 (+) 2454 WP_076639282.1 ATP-dependent RecD-like DNA helicase Machinery gene
  EGC57_RS07975 (EGC57_07985) - 1535909..1536391 (+) 483 WP_076639283.1 hypothetical protein -
  EGC57_RS07980 (EGC57_07990) dinB 1536484..1537578 (-) 1095 WP_020905451.1 DNA polymerase IV -
  EGC57_RS07985 (EGC57_07995) pflB 1537787..1540114 (+) 2328 WP_076639284.1 formate C-acetyltransferase -

Sequence

Protein


Download         Length: 817 a.a.        Molecular weight: 91505.44 Da        Isoelectric Point: 4.6398

>NTDB_id=283976 EGC57_RS07970 WP_076639282.1 1533365..1535818(+) (recD/recD2/recDB) [Streptococcus pyogenes strain M75]
MEYVFTGTVDRIIFENQANFFKILLLAIEDTDSDIDDFEIIITGTMADIIEGDDYTFWGELTQHPKYGQQLKLSRYQKIK
PSSSGLVNYFSSDHFKGIGKKTAEKIIALYGHNTIDHILEDPSKLETISGLSKANRQAFVAKLKLNYGTEQLIAGLVELG
LSNRFAFQAFEKYKEEALDLVKENPYQLVEDLQGFGFKMADALAENLGIESDSPKRFRAALLHCLLEESINRGDTYVQAR
QLLDFAITLLEDARQVECDPTAVAEQLSELIIEGKIKNSDTKLFDASLYFAEEGIASNISRLLDTPLSQSFSHNTIQTTI
QTVQKDFAITYDQVQQEAITKALTSKVFLLTGGPGTGKTTVIRGILQAYANLHQIDLDKKDLPILLAAPTGRAARRMNEL
TGLPSATIHRHLGLNGDNDYQAMEDYLDCDLLIVDEFSMVDTWLANQLLGAINSTTQVIIVGDSDQLPSVGPGQVLSDLL
KVNSLPQIALQKIFRQSQESTIVNLADQMRRGILAADFRDKKADRSYFEAQAAFIPDMIQKIVLSAIKSGIPAEEIQILA
PMYKGQAGINHLNQLMQELLNPLQGQTEFLFNDTHFRKGDKVLHLVNDAQLNVFNGDIGYITDLIPAKYTESKQDELILD
FDGSEVTYPRNEWLKLTLAYAMSIHKSQGSEFQVVILPITRQSGRLLQRNVIYTAITRSKSKLILLGEYTAFEYAIKHEG
DKRQTYLIERFQEQSDLASSQPNQELKSKEQTSLFSNTATLEDDSQKSSSQSTNSNPTENSQSDNDDFRLTPENYSTIDS
MIGLTEPDIALFFQKKS

Nucleotide


Download         Length: 2454 bp        

>NTDB_id=283976 EGC57_RS07970 WP_076639282.1 1533365..1535818(+) (recD/recD2/recDB) [Streptococcus pyogenes strain M75]
ATGGAATACGTTTTTACAGGTACTGTTGATCGTATCATTTTTGAAAACCAAGCTAATTTCTTTAAAATTCTCCTCCTTGC
CATTGAGGATACAGACAGTGACATTGACGACTTTGAAATCATTATCACAGGAACGATGGCTGACATTATTGAAGGAGATG
ACTACACCTTTTGGGGGGAATTGACCCAGCACCCTAAATACGGTCAACAACTCAAACTAAGCCGTTACCAAAAAATCAAA
CCTAGTTCATCTGGTTTGGTTAATTATTTCTCTAGTGACCATTTTAAGGGGATTGGTAAAAAAACAGCGGAGAAAATCAT
TGCACTATATGGTCATAATACCATTGACCATATTTTAGAAGACCCAAGCAAATTAGAAACTATCTCTGGCCTATCTAAGG
CTAATCGTCAAGCCTTTGTCGCTAAACTAAAATTGAATTACGGCACAGAGCAACTGATTGCTGGTCTCGTCGAACTTGGC
CTTAGCAACCGTTTTGCCTTTCAAGCGTTTGAGAAGTACAAAGAAGAGGCTCTTGACCTTGTTAAAGAAAATCCCTATCA
ATTAGTCGAAGATCTACAAGGTTTTGGGTTTAAGATGGCAGATGCTCTCGCTGAAAACTTAGGGATTGAGAGCGACTCTC
CGAAACGTTTTCGTGCAGCCCTCCTTCACTGTCTCTTGGAAGAATCCATCAATCGAGGAGATACTTATGTCCAAGCACGA
CAATTATTAGACTTTGCCATCACACTCCTTGAAGATGCACGTCAAGTAGAATGTGATCCTACTGCTGTGGCTGAACAACT
AAGCGAGTTAATCATAGAGGGCAAAATCAAAAACAGTGACACCAAACTGTTTGATGCTAGCCTTTATTTTGCTGAAGAAG
GGATTGCTAGCAACATCTCTCGTCTCTTAGATACTCCTTTAAGTCAGTCATTTAGTCATAATACCATTCAAACAACCATC
CAAACCGTTCAAAAAGACTTTGCCATCACCTATGACCAAGTGCAGCAAGAAGCCATTACTAAGGCCTTAACCAGCAAGGT
CTTTCTCCTAACAGGTGGTCCCGGAACAGGAAAAACAACTGTTATTCGAGGCATTTTGCAGGCTTACGCGAACCTGCATC
AGATTGATTTGGATAAAAAAGACCTTCCTATCTTGTTAGCAGCTCCAACAGGTCGAGCTGCACGTCGCATGAATGAGTTG
ACTGGACTTCCTAGCGCAACCATCCACAGGCACTTAGGCCTTAATGGCGACAACGATTACCAAGCCATGGAGGATTATCT
AGACTGCGACTTGCTGATTGTCGATGAATTTTCAATGGTGGATACCTGGCTTGCCAACCAGTTGTTAGGAGCGATTAACT
CAACAACTCAAGTGATTATTGTCGGAGATAGTGACCAGCTTCCTTCGGTTGGACCCGGTCAAGTCCTGTCAGATCTTTTA
AAAGTCAATAGCCTGCCCCAAATCGCCTTGCAAAAGATATTTCGTCAATCCCAAGAATCTACTATTGTCAATTTGGCAGA
CCAGATGCGTCGAGGAATCTTAGCTGCTGACTTTCGTGATAAAAAAGCTGACCGTTCTTATTTTGAAGCCCAAGCAGCCT
TTATCCCTGACATGATTCAAAAAATTGTCCTATCTGCTATTAAAAGTGGCATCCCTGCTGAGGAAATTCAAATTTTAGCG
CCTATGTACAAAGGACAAGCTGGCATCAATCATCTTAATCAACTCATGCAAGAACTTCTCAATCCCTTGCAAGGACAAAC
AGAATTTCTGTTCAATGATACGCATTTTCGTAAAGGTGATAAAGTCCTGCACTTAGTCAACGATGCTCAGTTGAATGTCT
TTAACGGGGATATTGGTTATATTACAGATTTGATTCCTGCTAAATACACCGAATCTAAGCAAGACGAATTAATCTTAGAT
TTTGACGGTAGCGAAGTCACGTACCCTAGAAATGAATGGCTAAAATTAACCCTGGCCTATGCCATGAGCATTCATAAATC
GCAAGGGAGTGAGTTTCAAGTGGTGATTTTACCTATCACACGCCAAAGCGGCCGACTCTTGCAACGAAATGTGATTTACA
CGGCCATTACTCGGTCTAAAAGTAAGTTAATTCTGTTGGGAGAATATACTGCCTTTGAGTATGCTATTAAACACGAAGGC
GATAAACGCCAAACCTACTTGATCGAACGCTTCCAAGAACAATCCGACTTAGCCTCCTCTCAACCTAACCAAGAGCTAAA
ATCAAAAGAGCAGACCTCCCTTTTTTCTAATACGGCAACCCTTGAGGACGACTCTCAAAAATCTTCCTCTCAATCAACAA
ACTCTAACCCCACTGAGAACTCTCAGTCAGATAATGATGATTTTAGGTTAACACCTGAGAATTATTCGACTATCGATTCG
ATGATAGGGCTTACAGAGCCAGATATTGCCCTCTTTTTCCAGAAAAAATCCTAG

Domains

Predicted by InterProScan.

AAA domain (AAA_30)

(331-522)

Helix-hairpin-helix containing domain (HHH_RecD2)

(147-236)

UvrD-like helicase C-terminal domain (UvrD_C_2)

(659-706)

ATP-dependent RecD-like DNA helicase SH3 domain (SH3_13)

(572-641)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  recD/recD2/recDB Bacillus subtilis subsp. subtilis str. 168

41.645

92.289

0.384

Multiple sequence alignment