NTDB

Overview

Name	radC	Type	Machinery gene
Locus tag	EGC57_RS04500	Genome accession	NZ_CP033621
Coordinates	857283..857963 (+)	Length	226 a.a.
NCBI ID	WP_002984709.1	Uniprot ID	A2REK0
Organism	Streptococcus pyogenes strain M75
Function	homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 852283..862963

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EGC57_RS04480 (EGC57_04490)	aphA	852710..853441 (+)	732	WP_002984720.1	acid phosphatase AphA	-
EGC57_RS04485 (EGC57_04495)	-	853619..855151 (+)	1533	WP_002995354.1	ClC family H(+)/Cl(-) exchange transporter	-
EGC57_RS04490 (EGC57_04500)	-	855314..855928 (+)	615	WP_076639639.1	SGNH/GDSL hydrolase family protein	-
EGC57_RS04495 (EGC57_04505)	-	856108..857235 (+)	1128	WP_021775237.1	AI-2E family transporter	-
EGC57_RS04500 (EGC57_04510)	radC	857283..857963 (+)	681	WP_002984709.1	DNA repair protein RadC	Machinery gene
EGC57_RS04505 (EGC57_04515)	-	857965..858660 (-)	696	WP_002989835.1	gamma-glutamyl-gamma-aminobutyrate hydrolase family protein	-
EGC57_RS04510 (EGC57_04520)	-	858670..859314 (-)	645	WP_002984705.1	redox-sensing transcriptional repressor Rex	-
EGC57_RS04515 (EGC57_04525)	-	859566..859913 (-)	348	WP_002989831.1	DUF1831 domain-containing protein	-
EGC57_RS04520 (EGC57_04530)	-	859903..861030 (-)	1128	WP_002989829.1	cysteine desulfurase family protein	-
EGC57_RS04525 (EGC57_04535)	-	861027..862007 (-)	981	WP_002984700.1	ribose-phosphate diphosphokinase	-
EGC57_RS04530 (EGC57_04540)	-	862147..862725 (-)	579	WP_002984698.1	CYTH domain-containing protein	-

Sequence

Protein

Download Length: 226 a.a. Molecular weight: 25742.96 Da Isoelectric Point: 7.3866

                                >NTDB_id=283942 EGC57_RS04500 WP_002984709.1 857283..857963(+) (radC) [Streptococcus pyogenes strain M75]

MYSIKCDDNKAMPRERLMRLGAESLSNQELLAILLRTGNKEKHVLELSSYLLSHLDSLADFKKMSLQELQHLAGIGKVKA

IEIKAMIELVSRILATDKTLTDSVLTSVQVAEKMMAALGDKKQEHLVVLYLDNQNRIIEEKTIFIGTVRRSLAEPREILY

YACKNMATSLIVIHNHPSGNIEPSSNDYCFTEKIKRSCEDLGIICLDHIIVSYKDYYSFREKSTLF

Nucleotide

Download Length: 681 bp

                                >NTDB_id=283942 EGC57_RS04500 WP_002984709.1 857283..857963(+) (radC) [Streptococcus pyogenes strain M75]

ATGTATTCTATAAAATGTGATGATAATAAAGCCATGCCAAGAGAACGTTTGATGCGACTAGGAGCAGAGTCTCTAAGTAA

TCAAGAATTATTAGCAATTTTATTACGAACAGGTAATAAAGAAAAGCATGTCTTAGAGCTGTCATCCTATCTTTTATCGC

ATTTAGACAGTCTGGCAGATTTTAAAAAGATGTCTTTGCAAGAATTACAACATTTGGCAGGTATAGGAAAAGTTAAAGCG

ATTGAAATTAAAGCTATGATTGAGTTGGTTTCCCGAATTTTAGCGACAGATAAGACATTAACTGATAGCGTATTAACCAG

TGTTCAGGTCGCTGAAAAAATGATGGCAGCTTTAGGAGATAAAAAACAAGAGCATTTAGTCGTATTGTATTTAGATAATC

AAAATCGTATTATTGAAGAAAAAACTATTTTTATTGGGACTGTCCGACGTTCACTTGCAGAACCAAGAGAAATTTTATAC

TATGCCTGTAAAAATATGGCGACTAGTCTCATTGTTATTCATAATCATCCTTCAGGAAATATTGAACCTAGTTCTAACGA

TTATTGCTTTACTGAAAAAATAAAACGATCATGTGAAGATTTAGGCATTATCTGTCTAGATCACATTATCGTTAGCTATA

AAGATTATTATAGTTTTCGAGAAAAATCAACCCTTTTTTAA

Domains

Predicted by InterProScan.

RadC-like JAB domain (RadC)

(107-222)

UPF0758 N-terminal (UPF0758_N)

(10-81)

Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.

3D structure

Source	ID	Structure
AlphaFold DB	A2REK0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.

Visualization of predicted probability:

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	H_a-value
radC	Streptococcus pneumoniae TIGR4	57.965	100	0.58
radC	Streptococcus pneumoniae R6	57.522	100	0.575
radC	Streptococcus pneumoniae D39	57.522	100	0.575
radC	Streptococcus gordonii str. Challis substr. CH1	55.752	100	0.558
ysxA/radC	Bacillus subtilis subsp. subtilis str. 168	43.119	96.46	0.416
radC	Haemophilus influenzae Rd KW20	37.9	96.903	0.367

Detailed information NTG0283942