Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   C7M45_RS09730 Genome accession   NZ_CP028255
Coordinates   1928023..1929162 (+) Length   379 a.a.
NCBI ID   WP_160212129.1    Uniprot ID   -
Organism   Leuconostoc mesenteroides strain SRCM102735     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1923023..1934162
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  C7M45_RS09710 (C7M45_01962) yycF 1923180..1923887 (+) 708 WP_010281559.1 response regulator YycF -
  C7M45_RS09715 (C7M45_01963) walK 1923955..1925820 (+) 1866 WP_025268546.1 cell wall metabolism sensor histidine kinase WalK -
  C7M45_RS09720 (C7M45_01964) - 1925810..1927102 (+) 1293 WP_025268545.1 hypothetical protein -
  C7M45_RS09725 (C7M45_01965) yycI 1927159..1927962 (+) 804 WP_160212128.1 two-component system regulatory protein YycI -
  C7M45_RS09730 (C7M45_01966) htrA 1928023..1929162 (+) 1140 WP_160212129.1 trypsin-like peptidase domain-containing protein Regulator
  C7M45_RS09735 (C7M45_01967) rlmH 1929792..1930271 (+) 480 WP_011680487.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  C7M45_RS09740 (C7M45_01968) - 1930365..1932530 (+) 2166 WP_025268544.1 YhgE/Pip domain-containing protein -
  C7M45_RS09745 (C7M45_01969) - 1932584..1933036 (+) 453 WP_011680485.1 Rrf2 family transcriptional regulator -
  C7M45_RS09750 (C7M45_01970) - 1933121..1933786 (-) 666 WP_010285559.1 NAD(P)H-hydrate epimerase -

Sequence

Protein


Download         Length: 379 a.a.        Molecular weight: 39268.52 Da        Isoelectric Point: 9.6793

>NTDB_id=283784 C7M45_RS09730 WP_160212129.1 1928023..1929162(+) (htrA) [Leuconostoc mesenteroides strain SRCM102735]
MVQSALTKTLLTGVIAGVVGGGAILYGQQGVQLLQNQNQKVSTTATSTKTIAKNATATSAYNKVSDAVVSVLNFTKSSQG
SYQESSEGSGVIYKKTDGSAFIVTNNHVITGAAKIQVMLHSGKKVTATLVGKDAMTDLAVLKIDGTDVTTTAQFGDSSKI
TVGENVLAIGSPLGSEYASSVTQGIISAKKRLVEETSENGQNYGGSTVIQTDAAINPGNSGGPLINFAGQVIGINSMKLS
TSSSGTSVEGMGFAIPSDQVVDIVNKLVKDGKVTRPAIGISLINLSEVTASEQKSTLKIPDSVTGGVVVMSLTNNGPADK
AGLKKYDVIVGINGKKVSSQADLREELYKHSLGDTITLTYYHQDTKQTVKVKLTQKLAS

Nucleotide


Download         Length: 1140 bp        

>NTDB_id=283784 C7M45_RS09730 WP_160212129.1 1928023..1929162(+) (htrA) [Leuconostoc mesenteroides strain SRCM102735]
ATGGTACAATCAGCATTAACAAAAACGTTGTTAACTGGCGTCATTGCTGGTGTTGTTGGTGGAGGAGCAATTTTGTATGG
GCAGCAGGGTGTACAATTGTTACAAAATCAAAATCAAAAAGTGAGTACGACAGCAACAAGTACAAAAACGATTGCCAAGA
ATGCAACTGCTACATCAGCTTATAATAAGGTATCAGATGCAGTTGTATCTGTATTGAACTTTACTAAATCCAGTCAAGGT
AGTTATCAAGAATCGTCAGAAGGTTCTGGCGTGATCTATAAAAAAACGGATGGATCGGCATTTATTGTAACGAATAATCA
CGTAATCACTGGAGCGGCTAAAATTCAAGTTATGCTGCACAGTGGGAAGAAAGTGACCGCTACATTAGTCGGCAAAGATG
CGATGACTGACTTAGCTGTTCTGAAAATCGACGGCACAGACGTTACAACAACTGCACAATTTGGCGATTCAAGTAAAATA
ACTGTTGGTGAAAATGTCTTGGCAATTGGTTCGCCGCTGGGATCTGAGTATGCTTCGTCAGTGACGCAAGGCATCATTTC
GGCCAAGAAAAGGTTAGTTGAGGAAACATCTGAAAATGGTCAAAATTATGGTGGATCCACGGTTATTCAGACGGATGCTG
CTATTAATCCTGGTAACTCAGGTGGACCATTAATCAACTTTGCAGGACAAGTTATTGGTATTAACTCAATGAAGTTATCA
ACATCTTCTTCTGGAACGAGCGTTGAGGGGATGGGTTTTGCAATTCCTTCTGATCAAGTCGTTGACATTGTTAACAAATT
AGTCAAAGATGGTAAAGTCACACGACCAGCAATTGGCATTAGTTTGATTAATTTGTCAGAAGTAACAGCTTCTGAGCAAA
AATCAACACTGAAAATTCCAGATAGCGTTACTGGTGGTGTTGTTGTAATGAGTTTGACTAACAATGGCCCAGCAGATAAA
GCTGGATTGAAGAAGTACGACGTTATTGTTGGCATTAATGGTAAAAAGGTCAGCTCACAGGCTGATCTGCGAGAAGAACT
CTACAAGCATTCGCTTGGGGACACAATAACATTGACTTATTATCATCAGGATACTAAGCAAACCGTCAAGGTTAAATTAA
CACAGAAATTGGCAAGCTAA

Domains

Predicted by InterproScan.

PDZ domain (PDZ_2)

(276-373)

Trypsin-like peptidase domain (Trypsin_2)

(88-234)

Peptidase family M50 (Peptidase_M50)

(221-375)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mitis NCTC 12261

52.394

93.668

0.491
  htrA Streptococcus gordonii str. Challis substr. CH1

48.549

100

0.485
  htrA Streptococcus pneumoniae D39

52.924

90.237

0.478
  htrA Streptococcus pneumoniae TIGR4

52.924

90.237

0.478
  htrA Streptococcus pneumoniae R6

52.924

90.237

0.478
  htrA Streptococcus pneumoniae Rx1

52.924

90.237

0.478
  htrA Streptococcus mutans UA159

52.647

89.71

0.472

Multiple sequence alignment