Detailed information NTG0281817

Bioinformatically predicted

Overview

• Name: comEC
• Type: Machinery gene
• Locus tag: LL14B4_RS09305
• Genome accession: NZ_CP028160
• Coordinates: 1905633..1907843 (-)
• Length: 736 a.a.
• NCBI ID: WP_109991124.1
• Uniprot ID: -
• Organism: Lactococcus lactis subsp. lactis strain 14B4
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1900633..1912843

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LL14B4_RS09275 (LL14B4_09265)	atpA	1900675..1902177 (-)	1503	WP_004255265.1	F0F1 ATP synthase subunit alpha	-
LL14B4_RS09280 (LL14B4_09270)	-	1902364..1902891 (-)	528	WP_012898339.1	F0F1 ATP synthase subunit delta	-
LL14B4_RS09285 (LL14B4_09275)	atpF	1902893..1903399 (-)	507	WP_010906128.1	F0F1 ATP synthase subunit B	-
LL14B4_RS09290 (LL14B4_09280)	atpB	1903414..1904127 (-)	714	WP_004255255.1	F0F1 ATP synthase subunit A	-
LL14B4_RS09295 (LL14B4_09285)	-	1904172..1904387 (-)	216	WP_004255250.1	F0F1 ATP synthase subunit C	-
LL14B4_RS09300 (LL14B4_09290)	-	1904572..1905348 (-)	777	WP_058206315.1	alpha/beta hydrolase	-
LL14B4_RS09305 (LL14B4_09295)	comEC	1905633..1907843 (-)	2211	WP_109991124.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
LL14B4_RS09310 (LL14B4_09300)	comEA	1907824..1908471 (-)	648	WP_033899944.1	ComEA family DNA-binding protein	Machinery gene
LL14B4_RS09315 (LL14B4_09305)	-	1908531..1909892 (-)	1362	WP_029344292.1	ABC transporter permease	-
LL14B4_RS09320 (LL14B4_09310)	-	1909889..1910821 (-)	933	WP_004255238.1	ABC transporter ATP-binding protein	-
LL14B4_RS09325 (LL14B4_09315)	-	1910926..1911324 (-)	399	WP_023188528.1	hypothetical protein	-
LL14B4_RS09330 (LL14B4_09320)	-	1911428..1911991 (-)	564	WP_109991125.1	GNAT family N-acetyltransferase	-

Sequence

Protein

• Length: 736 a.a.
• Molecular weight: 84553.21 Da
• Isoelectric Point: 9.6913

>NTDB_id=281817 LL14B4_RS09305 WP_109991124.1 1905633..1907843(-) (comEC) [Lactococcus lactis subsp. lactis strain 14B4]
MSCVLNKIPLIFLAYLSVILYFLIFNFNLICLILFIFSSLLALYRKYYLVIPFLLVMGSFFLVVKMDTIKNSENQPTTLS
KITMIPDTIQVNGDLLSFQGKERGQNYQVYETLKSKKEQKFYQNLSQNCQLSFTGNLQIPEKQRNFNGFDNQKYLASQNI
YRQITIDKINKIVLNDTFDLHVLRRKAIVWSQTHFPKPMNDYMTGLLFGFLSKDFNQMGDIYSSLGIIHLFALSGMQVNF
FIDWFRRIILRLGITREKLNIWQIPFSIFYAFMTGFSVSVLRALFQKNIRLNPLDNLAVTTFLLMIVSPKFLMTTGGQLT
LFYSFVISMINHKFSELKGIRKLLTESSVISLSVLPLLILDFHIFQPFSILLTIGFGFLFDVILLPLLLGTFLLSLIGYN
FNINHIFQILEWLIHEVDLPLHYPLVLGNPRPIELLILFFLIGLLIDNLFKKRRQIIFAGLIVCSFFICKNPIYPSITAV
DIGQGDSIFLQDKFNKETILIDTGGRLALPQESWQKPQSQTNAEKTLIPYLESVGVSQIDQLILTHTDADHVGDFLNLAD
KIKIKEIWVSPGELTNNHFVEKLKKANIAIHISKVGDKIPIFDSALQVLSNGYTGKGDNNDSIVTYGNFYHTKFLFTGDL
EQEGEKELLKNYPKLKVDVLKVGHHGSKTSSNSDFIKEINPKLALISVGEKNRYGHPNQETLETLKKNQIRILRTDQKGA
LKLMQINQHWRIQTVR

Nucleotide

• Length: 2211 bp

>NTDB_id=281817 LL14B4_RS09305 WP_109991124.1 1905633..1907843(-) (comEC) [Lactococcus lactis subsp. lactis strain 14B4]
ATGAGTTGTGTTTTGAATAAAATTCCTTTGATATTTTTAGCTTATCTTTCTGTTATCTTGTATTTTTTAATCTTCAATTT
TAATTTAATTTGTCTCATTTTGTTCATTTTTTCAAGTTTACTTGCCTTATATAGAAAATATTATTTAGTCATCCCATTTT
TATTAGTTATGGGAAGTTTTTTCTTAGTAGTAAAAATGGATACGATTAAGAATAGTGAAAATCAGCCAACCACTCTTTCC
AAAATTACAATGATCCCCGACACTATCCAAGTTAATGGTGATTTACTAAGTTTTCAAGGAAAAGAAAGAGGCCAAAATTA
TCAAGTTTACGAGACTCTAAAAAGTAAAAAAGAACAAAAATTTTATCAAAATCTAAGTCAAAATTGTCAGCTGAGTTTCA
CAGGAAACCTTCAAATTCCAGAAAAACAAAGAAATTTTAATGGATTCGATAATCAAAAGTATTTAGCGAGCCAGAATATT
TATCGGCAAATTACGATTGATAAAATTAATAAAATAGTTTTAAACGACACTTTTGACCTCCATGTTTTAAGACGAAAAGC
AATTGTCTGGTCACAAACTCATTTTCCAAAACCAATGAATGATTATATGACTGGCTTACTTTTTGGCTTTTTAAGTAAAG
ATTTTAATCAAATGGGAGACATTTACAGTTCATTAGGAATTATTCATCTTTTTGCCTTATCGGGAATGCAAGTTAATTTT
TTCATTGATTGGTTTCGTAGAATCATTCTTCGACTAGGAATAACGAGAGAAAAATTAAATATTTGGCAAATTCCCTTTTC
AATTTTTTATGCATTTATGACAGGATTTTCGGTTTCAGTATTACGAGCTTTATTTCAAAAAAATATTCGTCTAAATCCTT
TAGATAACCTAGCAGTGACAACCTTTCTTCTGATGATTGTCAGTCCTAAATTTTTAATGACAACAGGAGGACAACTAACT
TTATTTTATTCTTTTGTCATTTCAATGATTAATCATAAATTTTCAGAACTAAAAGGAATAAGAAAATTACTGACAGAATC
ATCAGTGATTTCTTTGAGTGTTTTACCTTTACTCATTTTGGATTTTCATATCTTTCAGCCTTTTTCAATTTTACTGACGA
TTGGCTTTGGCTTTTTATTTGATGTAATCTTATTGCCTTTACTATTAGGCACTTTTCTCTTGTCTCTAATTGGCTATAAT
TTTAATATAAATCATATTTTTCAAATTCTAGAATGGCTAATTCATGAGGTTGATTTACCCTTACATTATCCTTTGGTTTT
AGGGAATCCCCGGCCAATTGAATTATTAATCTTATTTTTCCTAATCGGTTTGTTAATTGATAATCTCTTTAAGAAAAGAA
GACAAATAATTTTTGCTGGCCTAATTGTTTGTAGTTTTTTTATTTGTAAAAATCCAATTTACCCCAGTATCACAGCAGTT
GATATTGGTCAAGGAGATAGTATTTTTTTGCAAGATAAATTTAATAAAGAAACAATTTTGATTGATACAGGCGGACGATT
AGCCCTTCCGCAAGAAAGTTGGCAAAAACCTCAAAGTCAAACAAATGCCGAAAAAACACTCATTCCATATCTTGAATCTG
TTGGAGTAAGTCAAATCGACCAGCTCATTTTGACGCATACGGACGCTGACCATGTTGGAGATTTTTTGAATTTAGCTGAT
AAAATAAAAATAAAAGAAATTTGGGTTAGCCCCGGTGAACTGACAAATAATCATTTTGTAGAAAAATTGAAGAAAGCAAA
TATTGCGATTCACATCAGTAAAGTTGGAGATAAAATTCCAATCTTTGATAGTGCTTTACAAGTTTTATCAAATGGTTATA
CAGGAAAAGGGGATAATAATGATTCTATCGTGACTTATGGAAATTTTTATCATACAAAATTTCTATTTACAGGGGATTTA
GAACAAGAAGGAGAAAAAGAACTGCTCAAGAATTATCCTAAATTGAAAGTTGATGTCTTAAAAGTAGGTCATCATGGCAG
TAAAACAAGTTCAAACTCTGACTTTATTAAAGAAATTAATCCCAAACTTGCCCTCATTTCGGTTGGAGAGAAAAATCGAT
ATGGACATCCCAATCAAGAAACTTTAGAAACATTAAAAAAAAACCAAATCAGAATACTGAGAACCGATCAAAAGGGAGCG
CTTAAACTAATGCAAATCAATCAACATTGGCGAATCCAAACAGTTAGATAA

Domains

Predicted by InterproScan.

• Domain of unknown function (DUF4131) (DUF4131) (27-171)

• Metallo-beta-lactamase superfamily (Lactamase_B) (483-689)

• Competence protein (Competence) (206-446)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC	Lactococcus lactis subsp. cremoris KW2	76.766	100	0.768
comEC/celB	Streptococcus mitis SK321	44.474	100	0.448
comEC/celB	Streptococcus mitis NCTC 12261	44.34	100	0.447
comEC/celB	Streptococcus pneumoniae TIGR4	43.338	100	0.438
comEC/celB	Streptococcus pneumoniae Rx1	43.069	100	0.435
comEC/celB	Streptococcus pneumoniae D39	43.069	100	0.435
comEC/celB	Streptococcus pneumoniae R6	43.069	100	0.435