Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   C5P47_RS01395 Genome accession   NZ_CP028140
Coordinates   254498..255259 (+) Length   253 a.a.
NCBI ID   WP_110410743.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain NGAS979     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 249498..260259
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  C5P47_RS01380 (C5P47_01375) - 249756..251324 (-) 1569 WP_032464169.1 ABC transporter substrate-binding protein/permease -
  C5P47_RS01385 (C5P47_01380) - 251522..253447 (+) 1926 WP_110410742.1 DUF2207 domain-containing protein -
  C5P47_RS01390 (C5P47_01385) - 253513..254352 (+) 840 WP_002991126.1 undecaprenyl-diphosphate phosphatase -
  C5P47_RS01395 (C5P47_01390) mecA 254498..255259 (+) 762 WP_110410743.1 adaptor protein MecA Regulator
  C5P47_RS01400 (C5P47_01395) - 255266..256435 (+) 1170 WP_002991122.1 MraY family glycosyltransferase -
  C5P47_RS01405 (C5P47_01400) sufC 256557..257327 (+) 771 WP_002986023.1 Fe-S cluster assembly ATPase SufC -
  C5P47_RS01410 (C5P47_01405) sufD 257422..258684 (+) 1263 WP_023612423.1 Fe-S cluster assembly protein SufD -
  C5P47_RS01415 (C5P47_01410) - 258715..259941 (+) 1227 WP_002991117.1 cysteine desulfurase -

Sequence

Protein


Download         Length: 253 a.a.        Molecular weight: 29065.75 Da        Isoelectric Point: 4.1622

>NTDB_id=281572 C5P47_RS01395 WP_110410743.1 254498..255259(+) (mecA) [Streptococcus pyogenes strain NGAS979]
MEMKQISETTLKITISMDDLEERGMELKDFLIPQEKTEEFFYSVMDELDLPDNFKDSGMLSFRVTPRKDRLDVFVTKSEI
NKDINLEDLAEFGDMSQMTPEDFFKSLEQSMREKGDVKAHEKLEKIEEIMEDVVEATLANQSEAADPSTNHESEPLDYVH
YVLDFSTITEAVAFAKTIDFSIEASELYKGSNCYHMTILLDIQQQPSYFANVMYARLIEHANPGSKTRAYLQEHGLQLML
DGAVEQLQKIELG

Nucleotide


Download         Length: 762 bp        

>NTDB_id=281572 C5P47_RS01395 WP_110410743.1 254498..255259(+) (mecA) [Streptococcus pyogenes strain NGAS979]
ATGGAAATGAAACAAATTAGCGAGACAACGCTAAAAATAACAATTAGTATGGACGATTTAGAAGAAAGAGGAATGGAGTT
GAAAGATTTCTTGATTCCTCAAGAAAAAACAGAAGAGTTTTTCTATTCTGTGATGGACGAACTCGATCTTCCAGATAATT
TTAAAGATAGTGGTATGCTTAGTTTTCGAGTGACTCCACGCAAGGACCGTCTAGATGTTTTTGTTACCAAATCTGAGATA
AATAAAGATATTAATCTTGAAGATTTAGCAGAGTTTGGTGATATGTCCCAAATGACTCCGGAAGATTTTTTCAAGAGCTT
GGAGCAATCCATGCGTGAAAAGGGAGATGTCAAAGCTCATGAAAAATTGGAAAAAATTGAAGAGATAATGGAAGATGTTG
TTGAAGCCACTCTAGCTAATCAGTCTGAGGCGGCTGATCCATCAACTAATCATGAGTCAGAACCTTTAGACTATGTCCAT
TATGTATTGGATTTTTCAACGATTACAGAGGCAGTGGCTTTTGCTAAAACGATTGATTTTTCGATAGAAGCTTCAGAGTT
ATATAAGGGGAGCAACTGCTACCATATGACTATTTTATTAGATATTCAGCAACAACCATCTTATTTTGCGAATGTCATGT
ATGCGAGATTGATTGAGCATGCAAACCCTGGATCAAAAACAAGAGCTTATTTACAAGAGCATGGCTTACAATTGATGCTT
GATGGTGCTGTTGAGCAATTACAAAAGATTGAGTTGGGATAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-247)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus mutans UA159

63.2

98.814

0.625
  mecA Streptococcus thermophilus LMD-9

56.225

98.419

0.553
  mecA Streptococcus thermophilus LMG 18311

55.422

98.419

0.545
  mecA Streptococcus pneumoniae Rx1

48.627

100

0.49
  mecA Streptococcus pneumoniae D39

48.627

100

0.49
  mecA Streptococcus pneumoniae R6

48.627

100

0.49
  mecA Streptococcus pneumoniae TIGR4

48.627

100

0.49

Multiple sequence alignment